Predicting myelosuppression of drugs from in silico models

Journal of Chemical Information and Modeling

Volumn 51, Issue 2, 2011, Pages 434-445

  Crivori, Patrizia ^a,c   Pennella, Giulia ^b   Magistrelli, Miriam ^a   Grossi, Pietro ^a   Giusti, Anna Maria ^b  

^a Attrition Reducing Technologies   (Italy)

^b Accelera   (Italy)

^c NERVIANO MEDICAL SCIENCES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; CHEMICAL ANALYSIS; DRUG INTERACTIONS; LEAD COMPOUNDS; MOLECULES; QUALITY CONTROL; STRUCTURAL ANALYSIS; TOXICITY; TUMORS;

ANTI-CANCER AGENTS; COMPUTATIONAL MODEL; DOSE LIMITING TOXICITY; LATENT VARIABLE MODELING; PRECLINICAL DEVELOPMENT; PROLIFERATING CELL POPULATION; SQUARED CORRELATION COEFFICIENTS; STRUCTURAL DIVERSITY;

DRUG DOSAGE;

DRUG;

ARTICLE; BIOLOGICAL MODEL; BONE MARROW; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; CONFORMATION; DRUG EFFECT; HEMATOPOIESIS; HUMAN; PRINCIPAL COMPONENT ANALYSIS;

BONE MARROW; COMPUTER SIMULATION; HEMATOPOIESIS; HUMANS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PHARMACEUTICAL PREPARATIONS; PRINCIPAL COMPONENT ANALYSIS;

EID: 79952136822     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci1003834     Document Type: Article

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