High-throughput in vitro hemotoxicity testing and in vitro cross-platform comparative toxicity

Expert Opinion on Drug Metabolism and Toxicology

Volumn 3, Issue 2, 2007, Pages 295-307

  Rich, Ivan N ^a  

^a HemoGenix Inc   (United States)

Author keywords

Bioluminescence; Colony forming assay; Comparative toxicity; Cytotoxicity; Frug discovery and development; Hemotoxicity; Proliferation

Indexed keywords

ANTINEOPLASTIC AGENT; DOXORUBICIN; METHYLCELLULOSE; VINBLASTINE; ADENOSINE TRIPHOSPHATE; DRUG;

ANEMIA; ARTICLE; BLOOD TOXICITY; CELL DIFFERENTIATION; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMATION; COLONY FORMING UNIT GM; CYTOTOXICITY; DRUG RESEARCH; HEMATOPOIETIC STEM CELL; HUMAN; IC 50; IN VITRO STUDY; INTERMETHOD COMPARISON; LD 50; NEUTROPENIA; NONHUMAN; PREDICTION; PROCESS DEVELOPMENT; STANDARDIZATION; THROMBOCYTOPENIA; TOXICITY TESTING; VALIDATION PROCESS; ANIMAL; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; DRUG EFFECT; DRUG MONITORING; DRUG TOXICITY; INTRACELLULAR FLUID; METABOLISM; METHODOLOGY; REPRODUCIBILITY; REVIEW;

ADENOSINE TRIPHOSPHATE; ANIMALS; DRUG MONITORING; DRUG TOXICITY; HEMATOPOIETIC STEM CELLS; HUMANS; INTRACELLULAR FLUID; PHARMACEUTICAL PREPARATIONS; REPRODUCIBILITY OF RESULTS;

EID: 34547199555     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425255.3.2.295     Document Type: Article

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