Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation

Carcinogenesis

Volumn 32, Issue 1, 2011, Pages 35-41

  Hur, Keun ^a   Niwa, Tohru ^a   Toyoda, Takeshi ^b,c   Tsukamoto, Tetsuya ^b,d   Tatematsu, Masae ^b   Yang, Han Kwang ^e   Ushijima, Toshikazu ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b AICHI CANCER CENTER HOSPITAL   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; CAGA PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; KI 67 ANTIGEN; METHYLNITROSOUREA; SODIUM CHLORIDE; TUMOR NECROSIS FACTOR; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CAGA PROTEIN, HELICOBACTER PYLORI; IRRITANT AGENT; SODIUM HYDROXIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL INFILTRATION; CELL PROLIFERATION; CHRONIC INFLAMMATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; FEMALE; GERBIL; HELICOBACTER FELIS; HELICOBACTER INFECTION; LYMPHOCYTIC INFILTRATION; MACROPHAGE INFILTRATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ADULT; AGED; ANIMAL; DRUG EFFECT; GASTRITIS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HELICOBACTER; HUMAN; IMMUNOLOGY; INFLAMMATION; MICROBIOLOGY; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; STOMACH MUCOSA;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELL PROLIFERATION; DNA METHYLATION; ETHANOL; FEMALE; GASTRIC MUCOSA; GASTRITIS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GERBILLINAE; HELICOBACTER; HELICOBACTER INFECTIONS; HUMANS; INFLAMMATION; IRRITANTS; MALE; MIDDLE AGED; SODIUM HYDROXIDE;

EID: 79952119029     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgq219     Document Type: Article

References (42)

1. Jones,P.A. et al. (2007) The epigenomics of cancer. Cell, 128, 683-692.
2. Esteller,M. (2008) Epigenetics in cancer. N. Engl. J. Med., 358, 1148-1159.
3. Issa,J.P. et al. (1994) Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon. Nat. Genet., 7, 536-540.
4. Hsieh,C.J. et al. (1998) Hypermethylation of the p16INK4a promoter in colectomy specimens of patients with long-standing and extensive ulcerative colitis. Cancer Res., 58, 3942-3945.
5. Issa,J.P. et al. (2001) Accelerated age-related CpG island methylation in ulcerative colitis. Cancer Res., 61, 3573-3577.
6. Toyota,M. et al. (2002) DNA methylation changes in gastrointestinal disease. J. Gastroenterol., 37 (suppl. 14), 97-101.
7. Kondo,Y. et al. (2000) Genetic instability and aberrant DNA methylation in chronic hepatitis and cirrhosis-a comprehensive study of loss of heterozygosity and microsatellite instability at 39 loci and DNA hypermethylation on 8 CpG islands in microdissected specimens from patients with hepatocellular carcinoma. Hepatology, 32, 970-979.
8. Maekita,T. et al. (2006) High levels of aberrant DNA methylation in Helicobacter pylori-infected gastric mucosae and its possible association with gastric cancer risk. Clin. Cancer Res., 12, 989-995.
9. Park,S.Y. et al. (2009) Comparison of CpG island hypermethylation and repetitive DNA hypomethylation in premalignant stages of gastric cancer, stratified for Helicobacter pylori infection. J. Pathol., 219, 410-416.
10. Nakajima,T. et al. (2006) Higher methylation levels in gastric mucosae significantly correlate with higher risk of gastric cancers. Cancer Epidemiol. Biomarkers Prev., 15, 2317-2321.
11. Kaise,M. et al. (2008) CpG island hypermethylation of tumor-suppressor genes in H. pylori-infected non-neoplastic gastric mucosa is linked with gastric cancer risk. Helicobacter, 13, 35-41.
12. Perri,F. et al. (2007) Aberrant DNA methylation in non-neoplastic gastric mucosa of H. Pylori infected patients and effect of eradication. Am. J. Gastroenterol., 102, 1361-1371.
13. Cotran,R.S. et al. (1989) Robbins Pathologic Basis of Disease. W.B. Saunders company, Philadelphia, PA.
14. Niwa,T. et al. (2010) Inflammatory processes triggered by Helicobacter pylori infection cause aberrant DNA methylation in gastric epithelial cells. Cancer Res., 70, 1430-1440.
15. Huang,J.Q. et al. (2003) Meta-analysis of the relationship between cagA seropositivity and gastric cancer. Gastroenterology, 125, 1636-1644.
16. Shibata,W. et al. (2006) CagA protein secreted by the intact type IV secretion system leads to gastric epithelial inflammation in the Mongolian gerbil model. J. Pathol., 210, 306-314.
17. Crabtree,J.E. et al. (2002) The mouse colonizing Helicobacter pylori strain SS1 may lack a functional cag pathogenicity island. Helicobacter, 7, 139-140; author reply, 140-141.
18. De Bock,M. et al. (2006) The effect of Helicobacter felis and Helicobacter bizzozeronii on the gastric mucosa in Mongolian gerbils: a sequential pathological study. J. Comp. Pathol., 135, 226-236.
19. De Bock,M. et al. (2006) Helicobacter felis and Helicobacter bizzozeronii induce gastric parietal cell loss in Mongolian gerbils. Microbes Infect., 8, 503-510.
20. Kang,J.Y. et al. (1995) Effect of capsaicin and chilli on ethanol induced gastric mucosal injury in the rat. Gut, 36, 664-669.
21. Suzuki,H. et al. (1999) Ethanol intake preceding Helicobacter pylori inoculation promotes gastric mucosal inflammation in Mongolian gerbils. J. Gastroenterol. Hepatol., 14, 1062-1069.
22. Furihata,C. et al. (1996) Cause and effect between concentration-dependent tissue damage and temporary cell proliferation in rat stomach mucosa by NaCl, a stomach tumor promoter. Carcinogenesis, 17, 401-406.
23. Tatematsu,M. et al. (1998) Induction of glandular stomach cancers in Helicobacter pylori-sensitive Mongolian gerbils treated with N-methyl-N-nitrosourea and N-methyl-N'-nitro-N-nitrosoguanidine in drinking water. Jpn. J. Cancer. Res., 89, 97-104.
24. D'Elios,M.M. et al. (1997) T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease. J. Immunol., 158, 962-967.
25. Fu,S. et al. (1999) Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis. Gastroenterology, 116, 1319-1329.
26. Yamaoka,Y. et al. (2005) Natural history of gastric mucosal cytokine expression in Helicobacter pylori gastritis in Mongolian gerbils. Infect. Immun., 73, 2205-2212.
27. Toyoda,T. et al. (2008) Synergistic upregulation of inducible nitric oxide synthase and cyclooxygenase-2 in gastric mucosa of Mongolian gerbils by a high-salt diet and Helicobacter pylori infection. Histol. Histopathol., 23, 593-599.
28. El-Omar,E.M. et al. (2000) Interleukin-1 polymorphisms associated with increased risk of gastric cancer. Nature, 404, 398-402.
29. Chan,A.O. et al. (2007) Association between Helicobacter pylori infection and interleukin 1beta polymorphism predispose to CpG island methylation in gastric cancer. Gut, 56, 595-597.
30. Lee,A. et al. (1997) A standardized mouse model of Helicobacter pylori infection: introducing the Sydney strain. Gastroenterology, 112, 1386-1397.
31. Cheng,H. et al. (1984) Methods for the determination of epithelial cell kinetic parameters of human colonic epithelium isolated from surgical and biopsy specimens. Gastroenterology, 86, 78-85.
32. Toyoda,T. et al. (2007) Inhibitory effect of nordihydroguaiaretic acid, a plant lignan, on Helicobacter pylori-associated gastric carcinogenesis in Mongolian gerbils. Cancer Sci., 98, 1689-1695.
33. Takagi,H. et al. (1995) Overexpression of DNA methyltransferase in myoblast cells accelerates myotube formation. Eur. J. Biochem., 231, 282-291.
34. Aoki,A. et al. (2001) Enzymatic properties of de novo-type mouse DNA (cytosine-5) methyltransferases. Nucleic Acids Res., 29, 3506-3512.
35. Kanai,Y. et al. (2007) Alterations of DNA methylation associated with abnormalities of DNA methyltransferases in human cancers during transition from a precancerous to a malignant state. Carcinogenesis, 28, 2434-2442.
36. Dieleman,L.A. et al. (1994) Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice. Gastroenterology, 107, 1643-1652.
37. Cappello,M. et al. (1992) Detection of mRNAs for macrophage products in inflammatory bowel disease by in situ hybridisation. Gut, 33, 1214-1219.
38. McLaughlan,J.M. et al. (1997) Interleukin-8 and inducible nitric oxide synthase mRNA levels in inflammatory bowel disease at first presentation. J. Pathol., 181, 87-92.
39. Llorente,L. et al. (1996) Cytokine gene expression in cirrhotic and noncirrhotic human liver. J. Hepatol., 24, 555-563.
40. Mihm,S. et al. (1997) Hepatic expression of inducible nitric oxide synthase transcripts in chronic hepatitis C virus infection: relation to hepatic viral load and liver injury. Hepatology, 26, 451-458.
41. Hmadcha,A. et al. (1999) Methylation-dependent gene silencing induced by interleukin 1beta via nitric oxide production. J. Exp. Med., 190, 1595- 1604.
42. Takeshima,H. et al. (2009) The presence of RNA polymerase II, active or stalled, predicts epigenetic fate of promoter CpG islands. Genome Res., 19, 1974-1982.