Computational Analysis of Activity and Selectivity Cliffs

Methods in Molecular Biology

Volumn 672, Issue , 2011, Pages 119-132

  Peltason, Lisa ^a   Bajorath, Jürgen ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Active compounds; Activity cliff; Selectivity cliff; Structure activity relationships; Structure selectivity relationships; Target selectivity

Indexed keywords

CATHEPSIN B; CATHEPSIN L; ENZYME INHIBITOR;

ANIMAL; ARTICLE; BIOLOGY; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER ANALYSIS; DRUG ANTAGONISM; HUMAN; METHODOLOGY; STRUCTURE ACTIVITY RELATION;

ANIMALS; CATHEPSIN B; CATHEPSIN L; CHEMISTRY, PHARMACEUTICAL; COMPUTATIONAL BIOLOGY; COMPUTING METHODOLOGIES; ENZYME INHIBITORS; HUMANS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

MLCS; MLOWN;

EID: 79952118736     PISSN: 10643745     EISSN: 19406029     Source Type: Book Series    
DOI: 10.1007/978-1-60761-839-3_4     Document Type: Chapter

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