Age, beta thalassaemia trait, and iron-deficient anaemia significantly affect reticulocyte indices in pre-school children

European Journal of Pediatrics

Volumn 169, Issue 9, 2010, Pages 1097-1104

  Chouliaras, Giorgos L ^a   Stamoulakatou, Alexandra ^b   Tsiftis, George ^a   Perissaki, Georgia ^b   Premetis, Evangelos ^b   Lycopoulou, Lilia ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^b AGHIA SOPHIA CHILDREN S HOSPITAL   (Greece)

Author keywords

Anaemia; Iron deficiency; Reference range; Reticulocyte indices; ROC analysis; thalassaemia heterozygosity

Indexed keywords

IRON;

AGE; AGE DISTRIBUTION; ARTICLE; BETA THALASSEMIA; BLOOD; CYTOLOGY; DIFFERENTIAL DIAGNOSIS; FEMALE; GREECE; HETEROZYGOTE; HUMAN; INFANT; IRON DEFICIENCY ANEMIA; MALE; MEAN CORPUSCULAR VOLUME; METABOLISM; METHODOLOGY; PRESCHOOL CHILD; RECEIVER OPERATING CHARACTERISTIC; RETICULOCYTE; RETICULOCYTE COUNT; SEX DIFFERENCE; SEX RATIO;

AGE DISTRIBUTION; AGE FACTORS; ANEMIA, IRON-DEFICIENCY; BETA-THALASSEMIA; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; ERYTHROCYTE INDICES; FEMALE; GREECE; HETEROZYGOTE; HUMANS; INFANT; IRON; MALE; RETICULOCYTE COUNT; RETICULOCYTES; ROC CURVE; SEX DISTRIBUTION; SEX FACTORS;

EID: 79952111092     PISSN: 03406199     EISSN: 14321076     Source Type: Journal    
DOI: 10.1007/s00431-010-1186-7     Document Type: Article

References (20)

1. Bakr AF, Sarette G (2006) Measurement of reticulocyte hemoglobin content to diagnose iron deficiency in Saudi children. Eur J Pediatr 165:442-445 (Pubitemid 43800523)
2. Brugnara C, Zurakowski D, DiCanzio J, Boyd T, Platt O (1999) Reticulocyte hemoglobin content to diagnose iron deficiency in children. JAMA 281:2225-2230 (Pubitemid 29275706)
3. Chouliaras GL, Premetis E, Tsiftis G, Drosatou P, Papassotiriou I, Stamoulakatou A, Lycopoulou L (2009) Serum transferrin receptors: distribution and diagnostic performance in pre-school children. Blood Cells Mol Dis 43:163-168
4. Grant CC, Wall CR, Brewster D, Nicholson R, Whitehall J, Super L, Pitcher L (2007) Policy statement on iron deficiency in pre-school-aged children. J Paediatr Child Health 43:513-521 (Pubitemid 47063299)
5. Halterman JS, Kaczorowski JM, Aligne CA, Auinger P, Szilagyi PG (2001) Iron deficiency and cognitive achievement among school-aged children and adolescents in the United States. Pediatrics 107:1381-1386 (Pubitemid 32525220)
6. Kanavakis E, Tzotzos S, Liapaki A, Metaxotou-Mavromati A, Kattamis C (1986) Frequency of alpha-thalassemia in Greece. Am J Hematol 22:225-232
7. Kattamis C, Metaxotou-Mavromati A, Wood WG, Nash JR, Weatherall DJ (1979) The heterogeneity of normal Hb A2-beta thalassaemia in Greece. Br J Haematol 42:109-123 (Pubitemid 9173422)
8. Markovic M, Majkic-Singh N, Ignjatovic S, Singh S (2007) Reticulocyte haemoglobin content vs. soluble transferrin receptor and ferritin index in iron deficiency anaemia accompanied with inflammation. Int J Lab Hematol 29:341-346 (Pubitemid 47373626)
9. Mast AE, Blinder MA, Lu Q, Flax S, Dietzen DJ (2002) Clinical utility of the reticulocyte hemoglobin content in the diagnosis of iron deficiency. Blood 99:1489-1491 (Pubitemid 34547111)
10. Mateos ME, De-la-Cruz J, Lopez-Laso E, Valdes MD, Nogales A (2008) Reticulocyte hemoglobin content for the diagnosis of iron deficiency. J Pediatr Hematol Oncol 30:539-542
11. McCann JC, Ames BN (2007) An overview of evidence for a causal relation between iron deficiency during development and deficits in cognitive or behavioral function. Am J Clin Nutr 85:931-945 (Pubitemid 46557905)
12. Sandoval C, Jayabose S, Eden AN (2004) Trends in diagnosis and management of iron deficiency during infancy and early childhood. Hematol Oncol Clin North Am 18:1423-1438, x (Pubitemid 39423421)
13. Segel GB, Hirsh MG, Feig SA (2002) Managing anemia in a pediatric office practice: part 2. Pediatr Rev 23:111-122
14. Segel GB, Hirsh MG, Feig SA (2002) Managing anemia in pediatric office practice: part 1. Pediatr Rev 23:75-84
15. Shaker M, Jenkins P, Ullrich C, Brugnara C, Nghiem BT, Bernstein H (2009) An economic analysis of anemia prevention during infancy. J Pediatr 154:44-49
16. Skarmoutsou C, Papassotiriou I, Traeger-Synodinos J, Stamou H, Ladis V, Metaxotou-Mavrommati A, Stamoulakatou A, Kanavakis E (2003) Erythroid bone marrow activity and red cell hemoglobinization in iron sufficient beta-thalassemia heterozygotes as reflected by soluble transferrin receptor and reticulocyte hemoglobin in content. Correlation with genotypes and Hb A(2) levels. Haematologica 88:631-636 (Pubitemid 36781589)
17. Stoffman N, Brugnara C, Woods ER (2005) An algorithm using reticulocyte hemoglobin content (CHr) measurement in screening adolescents for iron deficiency. J Adolesc Health 36:529
18. Ullrich C, Wu A, Armsby C, Rieber S, Wingerter S, Brugnara C, Shapiro D, Bernstein H (2005) Screening healthy infants for iron deficiency using reticulocyte hemoglobin content. JAMA 294:924-930 (Pubitemid 41215461)
19. WHO/CDC (2004) Assessing the iron status of populations. Report of a Joint World Health Organization/ Centers for Disease Control and Prevention Technical Consultation on the Assessment of Iron Status at the Population Level. Geneva, Switzerland
20. WHO/UNICEF/UNU (2001) Iron deficiency anaemia: assessment, prevention, and control. In: (WHO/NHD/01.3). World Health Organization, Geneva