Regional anaesthesia and analgesia in the neonate

Best Practice and Research: Clinical Anaesthesiology

Volumn 24, Issue 3, 2010, Pages 309-321

  Lönnqvist, Per Arne ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Adjuncts; Clonidine; Ketamine; Local anaesthetics; Neonatal; Neonates; Regional anaesthesia

Indexed keywords

BUPIVACAINE; CLONIDINE; EMLA; FENTANYL; KETAMINE; MORPHINE; OPIATE; ROPIVACAINE; SUFENTANIL; TETRACAINE; LOCAL ANESTHETIC AGENT;

ABDOMINAL SURGERY; ANALGESIA; ANESTHESIOLOGICAL PROCEDURE; ARTIFICIAL VENTILATION; CIRCUMCISION; CONTINUOUS INFUSION; DRUG SAFETY; EPIDURAL ANESTHESIA; HUMAN; LOCAL ANESTHESIA; PARALYTIC ILEUS; PEDIATRIC ANESTHESIA; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; PRACTICE GUIDELINE; PRIORITY JOURNAL; PRURITUS; REGIONAL ANESTHESIA; REVIEW; SPINAL ANESTHESIA; SURGICAL STRESS; TRACHEOESOPHAGEAL FISTULA; METHODOLOGY; NERVE BLOCK; NEWBORN;

ANALGESIA; ANESTHESIA, CONDUCTION; ANESTHETICS, LOCAL; HUMANS; INFANT, NEWBORN; NERVE BLOCK;

EID: 79952109551     PISSN: 15216896     EISSN: 1532169X     Source Type: Journal    
DOI: 10.1016/j.bpa.2010.02.012     Document Type: Review

References (74)

1. Wolf AR. Pain, nociception and the developing infant. Paediatric Anaesthesia 1999; 9(1): 7-17. (Pubitemid 29065899)
2. White MC & Wolf AR. Pain and stress in the human fetus. Best Practice & Research. Clinical Anaesthesiology 2004 Jun; 18(2): 205-220. (Pubitemid 38960612)
3. Taddio A, Katz J, Ilersich AL & Koren G. Effect of neonatal circumcision on pain response during subsequent routine vaccination. Lancet 1997 Mar 1; 349(9052): 599-603. (Pubitemid 27101886)
4. Brady-Fryer B, Wiebe N & Lander JA. Pain relief for neonatal circumcision. Cochrane Database of Systematic Reviews (Online) 2004 Oct 18; (4). CD004217.
5. Larsson BA, Jylli L, Lagercrantz H & Olsson GL. Does a local anaesthetic cream (EMLA) alleviate pain from heel-lancing in neonates? Acta Anaesthesiologica Scandinavica 1995 Nov; 39(8): 1028-1031.
6. Larsson BA, Norman M, Bjerring P et al. Regional variations in skin perfusion and skin thickness may contribute to varying efficacy of topical, local anaesthetics in neonates. Paediatric Anaesthesia 1996; 6(2): 107-110. (Pubitemid 126439104)
7. Weise KL & Nahata MC. EMLA for painful procedures in infants. Journal of Pediatric Health Care 2005 JaneFeb; 19(1): 42-47. (Pubitemid 40143272)
8. Lehr VT & Taddio A. Topical anesthesia in neonates: clinical practices and practical considerations. Seminars in Perinatology 2007 Oct; 31(5): 323-329. (Pubitemid 47495951)
9. Gjonaj ST, Lowenthal DB & Dozor AJ. Nebulized lidocaine administered to infants and children undergoing flexible bronchoscopy. Chest 1997 Dec; 112(6): 1665-1669. (Pubitemid 28007775)
10. Giaufré E, Dalens B & Gombert A. Epidemiology and morbidity of regional anesthesia in children: a one-year prospective survey of the French-Language Society of Pediatric Anesthesiologists. Anesthesia and Analgesia 1996 Nov; 83(5): 904-912. (Pubitemid 26365398)
11. Lederhaas G. Spinal anaesthesia in paediatrics. Best Practice & Research. Clinical Anaesthesiology 2003 Sep; 17(3): 365-376. (Pubitemid 38950002)
12. Kachko L, Simhi E, Tzeitlin E et al. Spinal anesthesia in neonates and infants-a single-center experience of 505 cases. Paediatric Anaesthesia 2007 Jul; 17(7): 647-653. (Pubitemid 46911079)
13. Rochette A, Raux O, Troncin R et al. Clonidine prolongs spinal anesthesia in newborns: a prospective dose-ranging study. Anesthesia and Analgesia 2004 Jan; 98(1): 56-59. (Pubitemid 38029842)
14. Humphreys N, Bays SM, Parry AJ et al. Spinal anesthesia with an indwelling catheter reduces the stress response in pediatric open heart surgery. Anesthesiology 2005 Dec; 103(6): 1113-1120. (Pubitemid 41692492)
15. Bösenberg A. Neuraxial blockade and cardiac surgery in children. Paediatric Anaesthesia 2003 Sep; 13(7): 559-560.
16. Jöhr M, Seiler SJ & Berger TM. Caudal anesthesia with ropivacaine in an awake 1,090-g baby. Anesthesiology 2000 Aug; 93 (2): 593. (Pubitemid 30620350)
17. Schuepfer G, Konrad C, Schmeck J et al. Generating a learning curve for pediatric caudal epidural blocks: an empirical evaluation of technical skills in novice and experienced anesthetists. Regional Anesthesia and Pain Medicine 2000 JuleAug; 25(4): 385-388. (Pubitemid 30480432)
18. Roberts SA, Guruswamy V & Galvez I. Caudal injectate can be reliably imaged using portable ultrasoundea preliminary study. Paediatric Anaesthesia 2005 Nov; 15(11): 948-952. (Pubitemid 43961310)
19. Breschan C, Krumpholz R, Likar R et al. Can a dose of 2 μg.kg(-1) caudal clonidine cause respiratory depression in neonates? Paediatric Anaesthesia 1999; 9(1): 81-83. (Pubitemid 29065911)
20. Breschan C, Hellstrand E, Likar R & Lönnquist PA. Early signs of toxicity and "subtoxic" conditions in infant monitoring. Bupivacaine plasma levels following caudal anesthesia. Anaesthesist 1998 Apr; 47(4): 290-294.
21. Masters-Harte LD & Abdel-Rahman SM. Sucrose analgesia for minor procedures in newborn infants. The Annals of Pharmacotherapy 2001 Jul-Aug; 35(7-8): 947-952. (Pubitemid 32678722)
22. Bianchi A, Dickson AP & Alizai NK. Elective delayed midgut reduction-No anesthesia for gastroschisis: selection and conversion criteria. Journal of Pediatric Surgery 2002 Sep; 37(9): 1334-1336. (Pubitemid 34977613)
23. Bösenberg AT. Epidural analgesia for major neonatal surgery. Paediatric Anaesthesia 1998; 8(6): 479-483. (Pubitemid 28523408)
24. Bösenberg AT, Wiersma R & Hadley GP. Oesophageal atresia: caudo-thoracic epidural anesthesia reduces the need for post-operative ventilatory support. Pediatric Surgery International 1992; 7: 289-291.
25. Wolf AR, Eyres RL, Laussen PC et al. Effect of extradural analgesia on stress responses to abdominal surgery in infants. British Journal of Anaesthesia 1993 Jun; 70(6): 654-660. (Pubitemid 23169060)
26. Hoehn T, Jetzek-Zader M, Blohm M & Mayatepek E. Early peristalsis following epidural analgesia during abdominal surgery in an extremely low birth weight infant. Paediatric Anaesthesia 2007 Feb; 17(2): 176-179. (Pubitemid 46089385)
27. Llewellyn N & Moriarty A. The national pediatric epidural audit. Paediatric Anaesthesia 2007 Jun; 17(6): 520-533. (Pubitemid 46718193)
28. Chalkiadis G. The rise and fall of continuous epidural infusions in children. Paediatric Anaesthesia 2003 Feb; 13(2): 91-93. (Pubitemid 36246273)
29. Guinard JP & Borboen M. Probable venous air embolism during caudal anesthesia in a child. Anesthesia and Analgesia 1993 May; 76(5): 1134-1135. (Pubitemid 23139472)
30. Schwartz N & Eisenkraft JB. Probable venous air embolism during epidural placement in an infant. Anesthesia and Analgesia 1993 May; 76(5): 1136-1138. (Pubitemid 23139473)
31. Flandin-Bléty C & Barrier G. Accidents following extradural analgesia in children. The results of a retrospective study. Paediatric Anaesthesia 1995; 5(1): 41-46.
32. Sethna NF & Berde CB. Venous air embolism during identification of the epidural space in children. Anesthesia and Analgesia 1993 May; 76(5): 925-927. (Pubitemid 23139437)
33. Sethna NF & McGowan Jr. FX. Do results from studies of a simulated epidural test dose improve our ability to detect unintentional epidural vascular puncture in children? Paediatric Anaesthesia 2005 Sep; 15(9): 711-715. (Pubitemid 43960886)
34. Kasai T, Yaegashi K, Hirose M et al. Spinal cord injury in a child caused by an accidental dural puncture with a single-shot thoracic epidural needle. Anesthesia and Analgesia 2003 Jan; 96(1): 65-67. (Pubitemid 36042034)
35. Allison CE, Aronson DC, Geukers VG et al. Paraplegia after thoracotomy under combined general and epidural anesthesia in a child. Paediatric Anaesthesia 2008 Jun; 18(6): 539-542. (Pubitemid 351600203)
36. Bösenberg AT, Bland BA, Schulte-Steinberg O et al. Thoracic epidural anesthesia via caudal route in infants. Anesthesiology 1988 Aug; 69(2): 265-269.
37. Gunter JB & Eng C. Thoracic epidural anesthesia via the caudal approach in children. Anesthesiology 1992 Jun; 76(6): 935-938.
38. Van Niekerk J, Bax-Vermeire BM, Geurts JW et al. Epidurography in premature infants. Anaesthesia 1990 Sep; 45(9): 722-725. (Pubitemid 20314708)
39. Tsui BC, Wagner A, Cave D et al. Thoracic and lumbar epidural analgesia via the caudal approach using electrical stimulation guidance in pediatric patients: a review of 289 patients. Anesthesiology 2004 Mar; 100(3): 683-689. (Pubitemid 38268890)
40. Willschke H, Marhofer P, Bösenberg A et al. Epidural catheter placement in children: comparing a novel approach using ultrasound guidance and a standard loss-of-resistance technique. British Journal of Anaesthesia 2006 Aug; 97(2): 200-207. (Pubitemid 44295706)
41. Willschke H, Bosenberg A, Marhofer P et al. Epidural catheter placement in neonates: sonoanatomy and feasibility of ultrasonographic guidance in term and pretermneonates. Regional Anesthesia and Pain Medicine 2007 JaneFeb;32(1): 34-40. (Pubitemid 44969599)
42. Bösenberg AT & Kimble FW. Infraorbital nerve block in neonates for cleft lip repair: anatomical study and clinical application. British Journal of Anaesthesia 1995 May; 74(5): 506-508.
43. Willschke H, Marhofer P, Bösenberg A et al. Ultrasonography for ilioinguinal/iliohypogastric nerve blocks in children. British Journal of Anaesthesia 2005 Aug; 95(2): 226-230. (Pubitemid 41487150)
44. Weintraud M, Marhofer P, Bösenberg A et al. Ilioinguinal/ iliohypogastric blocks in children: where do we administer the local anesthetic without direct visualization? Anesthesia and Analgesia 2008 Jan; 106(1): 89-93.
45. Weintraud M, Lundblad M,Kettner SC et al. Ultrasound versus landmark-based technique for ilioinguinal-iliohypogastric nerve blockade in children: the implications onplasma levels of ropivacaine. Anesthesia and Analgesia 2009May; 108(5): 1488-1492.
46. Breschan C, Kraschl R, Jost R et al. Axillary brachial plexus block for treatment of severe forearm ischemia after arterial cannulation in an extremely low birth-weight infant. Paediatric Anaesthesia 2004 Aug; 14(8): 681-684. (Pubitemid 39070565)
47. Bielsky A, Efrat R & Suresh S. Postoperative analgesia in neonates after major abdominal surgery: 'TAP' our way to success!. Paediatric Anaesthesia 2009 May; 19(5): 541-542.
48. Karmakar MK, Booker PD, Franks R et al. Continuous extrapleural paravertebral infusion of bupivacaine for postthoracotomy analgesia in young infants. British Journal of Anaesthesia 1996 Jun; 76(6): 811-815. (Pubitemid 26175634)
49. Berta E, Spanhel J, Smakal O et al. Single injection paravertebral block for renal surgery in children. Paediatric Anaesthesia 2008 Jul; 18(7): 593-597. (Pubitemid 351777483)
50. Tirotta CF, Munro HM, Salvaggio J et al. Continuous incisional infusion of local anesthetic in pediatric patients following open heart surgery. Paediatric Anaesthesia 2009 Jun; 19(6): 571-576.
51. Ouaki J, Dadure C, Bringuier S et al. Continuous infusion of ropivacaïne: an optimal postoperative analgesia regimen for iliac crest bone graft in children. Paediatric Anaesthesia 2009 Sep; 19(9): 887-891.
52. Willschke H, Bösenberg A, Marhofer P et al. Ultrasonographic-guided ilioinguinal/iliohypogastric nerve block in pediatric anesthesia: what is the optimal volume? Anesthesia and Analgesia 2006 Jun; 102(6): 1680-1684. (Pubitemid 43799837)
53. http://lipidrescue.squarespace.com.
54. http://www.aagbi.org/publications/guidelines/docs/latoxicity07.pdf.
55. Shah S, Gopalakrishnan S, Apuya J et al. Use of Intralipid in an infant with impending cardiovascular collapse due to local anesthetic toxicity. Journal of Anesthesia 2009; 23(3): 439-441.
56. Hiller DB, Gregorio GD, Ripper R et al. Epinephrine impairs lipid resuscitation from bupivacaine overdose: a threshold effect. Anesthesiology 2009 Sep; 111(3): 498-505.
57. Zausig YA, Zink W, Keil M et al. Lipid emulsion improves recovery from bupivacaine-induced cardiac arrest, but not from ropivacaine- or mepivacaine-induced cardiac arrest. Anesthesia and Analgesia 2009 Oct; 109(4): 1323-1326.
58. Guldogus F, Baris YS, Baris S et al. Comparing tissue coring potentials of hollow needles without stylet and caudal needles with stylet: an experimental study. European Journal of Anaesthesiology 2008 Jun; 25(6): 498-501. (Pubitemid 351629971)
59. Berde CB. Toxicity of local anesthetics in infants and children. The Journal of Pediatrics 1993 May; 122(5 Pt 2): S14-S20. (Pubitemid 23132077)
60. Larsson BA, Lönnqvist PA & Olsson GL. Plasma concentrations of bupivacaine in neonates after continuous epidural infusion. Anesthesia and Analgesia 1997 Mar; 84(3): 501-505. (Pubitemid 27100378)
61. Bösenberg AT, Thomas J, Lopez T et al. Plasma concentrations of ropivacaine following a single-shot caudal block of 1, 2 or 3 mg/kg in children. Acta Anaesthesiologica Scandinavica 2001 Nov; 45(10): 1276-1280. (Pubitemid 33063415)
62. Bösenberg AT, Thomas J, Cronje L et al. Pharmacokinetics and efficacy of ropivacaine for continuous epidural infusion in neonates and infants. Paediatric Anaesthesia 2005 Sep; 15(9): 739-749. (Pubitemid 43960890)
63. Chalkiadis GA & Anderson BJ. Age and size are the major covariates for prediction of levobupivacaine clearance in children. Paediatric Anaesthesia 2006 Mar; 16(3): 275-282.
64. Sanders JC. Paediatric regional anaesthesia, a survey of practice in the United Kingdom. British Journal of Anaesthesia 2002 Nov; 89(5): 707-710. (Pubitemid 35277218)
65. Eich C & Strauss J. Prompt and powerful effect of a practice guideline on caudal additives. Paediatric Anaesthesia 2009 Mar; 19(3): 271-272.
66. Hager H, Marhofer P, Sitzwohl C et al. Caudal clonidine prolongs analgesia from caudal S(+)-ketamine in children. Anesthesia and Analgesia 2002 May; 94(5): 1169-1172. (Pubitemid 34441828)
67. Lönnqvist PA. Adjuncts to caudal block in children-Quo vadis? British Journal of Anaesthesia 2005 Oct; 95(4): 431-433.
68. De Negri P, Ivani G, Visconti C et al. The dose-response relationship for clonidine added to a postoperative continuous epidural infusion of ropivacaine in children. Anesthesia and Analgesia 2001 Jul; 93(1): 71-76. (Pubitemid 32601156)
69. Cucchiaro G, Adzick SN, Rose JB et al. A comparison of epidural bupivacaine-fentanyl and bupivacaine-clonidine in children undergoing the Nuss procedure. Anesthesia and Analgesia 2006 Aug; 103(2): 322-327. (Pubitemid 44140630)
70. Cucchiaro G & Ganesh A. The effects of clonidine on postoperative analgesia after peripheral nerve blockade in children. Anesthesia and Analgesia 2007 Mar; 104(3): 532-537.
71. Taddio A, Goldbach M, Ipp M et al. Effect of neonatal circumcision on pain responses during vaccination in boys. Lancet 1995 Feb 4; 345(8945): 291-292.
72. Armitage EN. Caudal blocks in children. Anaesthesia 1979; 34: 396.
73. Mazoit JX & Lonnqvist PA. Local anaesthetics and their adjuncts. In Bingham R, Lloyd-Thomas A & Sury M (eds.). Hatch & Sumner's textbook of paediatric anaesthesia. 3rd edn. Hodder Arnold, 2009, pp. 211-226.
74. Bartocci M, Lundeberg S, Lönnqvist PA. Local anesthesia via subcutaneous catheter after thoracotomy in premature infants. World Congress of Pediatric Pain, Vancouver, 2006 (abstract).