Shedding and infection dynamics of porcine circovirus type 2 (PCV2) after natural exposure

Veterinary Microbiology

Volumn 149, Issue 1-2, 2011, Pages 225-229

  Patterson, A R ^a   Madson, D M ^a   Halbur, P G ^a   Opriessnig, T ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

Epidemiology; Natural infection; PCV2; Porcine circovirus type 2; Shedding

Indexed keywords

VIRUS DNA;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; CIRCOVIRIDAE INFECTION; CIRCOVIRUS; CONTROLLED STUDY; DNA DETERMINATION; FECES; MOUTH; NONHUMAN; NOSE; NOSE SECRETION; NOSE SMEAR; PORCINE CIRCOVIRUS TYPE 2; PORCINE CIRCOVIRUS TYPE 2 INFECTION; SWINE; VIRUS DETECTION; VIRUS SHEDDING;

ANIMALS; ANTIBODIES, VIRAL; CIRCOVIRIDAE INFECTIONS; CIRCOVIRUS; DNA, VIRAL; FECES; IMMUNOGLOBULIN G; MOUTH; NOSE; POLYMERASE CHAIN REACTION; SWINE; SWINE DISEASES; VIRUS SHEDDING;

PORCINE CIRCOVIRUS 2; SUIDAE;

EID: 79952101810     PISSN: 03781135     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vetmic.2010.10.021     Document Type: Article

References (21)

1. Allan G.M., McNeilly F., McNair I., Meehan B., Marshall M., Ellis J., Lasagna C., Boriosi G., Krakowka S., Reynaud G., Boeuf-Tedeschi L., Bublot M., Charreyre C. Passive transfer of maternal antibodies to PCV2 protects against development of post-weaning multisystemic wasting syndrome (PMWS): experimental infections and a field study. Pig J. 2002, 50:59-67.
2. Bolin S.R., Stoffregen W.C., Nayar G.P., Hamel A.L. Postweaning multisystemic wasting syndrome induced after experimental inoculation of cesarean-derived, colostrum-deprived piglets with type 2 porcine circovirus. J. Vet. Diagn. Invest. 2001, 13:185-194.
3. Carasova P., Celer V., Takacova K., Trundova M., Molinkova D., Lobova D., Smola J. The levels of PCV2 specific antibodies and viremia in pigs. Res. Vet. Sci. 2007, 83:274-278.
4. Dorr P.M., Baker R.B., Almond G.W., Wayne S.R., Gebreyes W.A. Epidemiologic assessment of porcine circovirus type 2 coinfection with other pathogens in swine. J. Am. Vet. Med. Assoc. 2007, 230:244-250.
5. Grau-Roma L., Hjulsager C.K., Sibila M., Kristensen C.S., López-Soria S., Enøe C., Casal J., Bøtner A., Nofrarías M., Bille-Hansen V., Fraile L., Baekbo P., Segalés J., Larsen L.E. Infection, excretion and seroconversion dynamics of porcine circovirus type 2 (PCV2) in pigs from post-weaning multisystemic wasting syndrome (PMWS) affected farms in Spain and Denmark. Vet. Microbiol. 2009, 135:272-282.
6. Halbur P.G., Paul P.S., Frey M.L., Landgraf J., Eernisse K., Meng X.J., Lum M.A., Andrews J.J., Rathje J.A. Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus. Vet. Pathol. 1995, 32:648-660.
7. Harding J.C.S., Clark E.G., Strokappe J.H., Willson P.I., Ellis J.A. Postweaning multisystemic wasting syndrome: epidemiology and clinical presentation. Swine Health Prod. 1998, 6:249-254.
8. James F.C., McCulloch C.E. Multivariate-analysis in ecology and systematics-panacea or pandora box. Annu. Rev. Ecol. Syst. 1990, 21:129-166.
9. McIntosh K.A., Harding J.C., Ellis J.A., Appleyard G.D. Detection of Porcine circovirus type 2 viremia and seroconversion in naturally infected pigs in a farrow-to-finish barn. Can. J. Vet. Res. 2006, 70:58-61.
10. Mengeling W.L., Ridpath J.F., Vorwald A.C. Size and antigenic comparisons among the structural proteins of selected autonomous parvoviruses. J. Gen. Virol. 1988, 69:825-837.
11. Nawagitgul P., Harms P.A., Morozov I., Thacker B.J., Sorden S.D., Lekcharoensuk C., Paul P.S. Modified indirect porcine circovirus (PCV) type 2-based and recombinant capsid protein (ORF2)-based enzyme-linked immunosorbent assays for detection of antibodies to PCV. Clin. Diagn. Lab. Immunol. 2002, 9:33-40.
12. Opriessnig T., Halbur P.G., Yu S., Thacker E.L., Fenaux M., Meng X.J. Effects of the timing of the administration of Mycoplasma hyopneumoniae bacterin on the development of lesions associated with porcine circovirus type 2. Vet. Rec. 2006, 158:149-154.
13. Opriessnig T., McKeown N.E., Zhou E.M., Meng X.J., Halbur P.G. Genetic and experimental comparison of porcine circovirus type 2 (PCV2) isolates from cases with and without PCV2-associated lesions provides evidence for differences in virulence. J. Gen. Virol. 2006, 87:2923-2932.
14. Opriessnig T., Prickett J.R., Madson D.M., Shen H.G., Juhan N.M., Pogranichniy R., Meng X.J., Halbur P.G. Porcine circovirus type 2 (PCV2)-infection and re-inoculation with homologous or heterologous strains: virological, serological, pahtological and clinical effects in growing pigs. Vet. Res. 2010, 41:31.
15. Opriessnig T., Thacker E.L., Yu S., Fenaux M., Meng X.J., Halbur P.G. Experimental reproduction of postweaning multisystemic wasting syndrome in pigs by dual infection with Mycoplasma hyopneumoniae and porcine circovirus type 2. Vet. Pathol. 2004, 41:624-640.
16. Opriessnig T., Yu S., Gallup J.M., Evans R.B., Fenaux M., Pallares F., Thacker E.L., Brockus C.W., Ackermann M.R., Thomas P., Meng X.J., Halbur P.G. Effect of vaccination with selective bacterins on conventional pigs infected with type 2 porcine circovirus. Vet. Pathol. 2003, 40:521-529.
17. Opriessnig T., Yu S., Thacker E.L., Halbur P.G. Derivation of porcine circovirus type 2-negative pigs from positive breeding herds. J. Swine Health Prod. 2004, 12:186-191.
18. Segalés J., Calsamiglia M., Olvera A., Sibila M., Badiella L., Domingo M. Quantification of porcine circovirus type 2 (PCV2) DNA in serum and tonsillar, nasal, tracheo-bronchial, urinary and faecal swabs of pigs with and without postweaning multisystemic wasting syndrome (PMWS). Vet. Microbiol. 2005, 111:223-229.
19. Shen, H., Wang, C., Madson, D., Opriessnig, T., 2010. High prevalence of porcine circovirus viremia in newborn piglets in five clinically normal swine breeding herds in North America. Prev. Vet. Med. [Epub ahead of print], doi:10.1016/j.prevetmed.2010.09.020.
20. Sibila M., Calsamiglia M., Segalés J., Blanchard P., Badiella L., Le Dimna M., Jestin A., Domingo M. Use of a polymerase chain reaction assay and an ELISA to monitor porcine circovirus type 2 infection in pigs from farms with and without postweaning multisystemic wasting syndrome. Am. J. Vet. Res. 2004, 65:88-92.
21. Sorden S.D., Harms P.A., Nawagitgul P., Cavanaugh D., Paul P.S. Development of a polyclonal-antibody-based immunohistochemical method for the detection of type 2 porcine circovirus in formalin-fixed, paraffin-embedded tissue. J. Vet. Diagn. Invest. 1999, 11:528-530.