Retinoic acid induces myoblasts transdifferentiation into premeiotic Stra8-positive cells

Cell Biology International

Volumn 35, Issue 4, 2011, Pages 365-372

  Jia, Wenwen ^a   Cheng, De ^a   Chen, Shuai ^a   Lei, Lei ^a   Wang, Huayan ^a,b  

^a Shaanxi Center for Stem Cell Engineering and Technology   (China)

^b NORTHWEST A F UNIVERSITY   (China)

Author keywords

C2C12 myoblast; Embryonic carcinoma cell; Retinoic acid; Spermatogenesis; Stra8; Transdifferentiation

Indexed keywords

MOUSE VASA HOMOLOGUE PROTEIN; PROTAMINE; PROTAMINE P1; RETINOIC ACID; RNA HELICASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STRUCTURE; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; DIPLOIDY; DNA CONTENT; EMBRYO; GENE; GENE EXPRESSION; MARKER GENE; MEIOSIS; MOUSE; MYOBLAST; NONHUMAN; PHENOTYPIC PLASTICITY; PROMOTER REGION; SPERMATOGENESIS; SPERMATOGONIUM; STIMULATED BY RETINOIC ACID GENE 8;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL TRANSDIFFERENTIATION; GENE EXPRESSION; MALE; MICE; MYOBLASTS; NIH 3T3 CELLS; PROTEINS; SPERMATOGENESIS; SPERMATOGONIA; TRETINOIN;

EID: 79952075275     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20100610     Document Type: Article

References (25)

1. Aflatoonian B, Moore H. Germ cells from mouse and human embryonic stem cells. Reproduction 2006;132:699-707.
2. Bowles J, Knight D, Smith C, Wilhelm D, Richman J, Mamiya S et al. Retinoid signaling determines germ cell fate in mice. Science 2006;312:596-600.
3. Chang H, Matzuk MM. Smad5 is required for mouse primordial germ cell development. Mech Dev 2001;104:61-7.
4. Chung SS, Wolgemuth DJ. Role of retinoid signaling in the regulation of spermatogenesis. Cytogenet Genome Res 2004;105:189-202.
5. Dyce PW, Wen L, Li J. In vitro germline potential of stem cells derived from fetal porcine skin. Nat Cell Biol 2006;8:384-90.
6. Feng R, Desbordes SC, Xie H, Tillo ES, Pixley F, Stanley ER et al. PU.1 and C/EBPalpha/beta convert fibroblasts into macrophage-like cells. Proc Natl Acad Sci USA 2008;105:6057-62.
7. Geijsen N, Horoschak M, Kim K, Gribnau J, Eggan K, Daley GQ. Derivation of embryonic germ cells and male gametes from embryonic stem cells. Nature 2004;427:148-54.
8. Giuili G, Tomljenovic A, Labrecque N, Oulad-Abdelghani M, Rassoulzadegan M, Cuzin F. Murine spermatogonial stem cells: targeted transgene expression and purification in an active state. EMBO Rep 2002;3:753-9.
9. Katagiri T, Yamaguchi A, Komaki M, Abe E, Takahashi N, Ikeda T et al. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. J Cell Biol 1994;127:1755-66.
10. Li W, Dou ZY, Hua JL, Wang HY. Activation of Stra 8 gene during the differentiation of spermatogonial stem cells. Sheng Wu Gong Cheng Xue Bao 2007;23:639-44.
11. Matsui Y, Hayashi K. Epigenetic regulation for the induction of meiosis. Cell Mol Life Sci 2007;64:257-62.
12. Miyamoto T, Sengoku K, Takuma N, Hasuike S, Hayashi H, Yamauchi T et al. Isolation and expression analysis of the testis-specific gene, STRA8, stimulated by retinoic acid gene 8. J Assist Reprod Genet 2002;19:531-5.
13. Moran JL, Li Y, Hill AA, Mounts WM, Miller CP. Gene expression changes during mouse skeletal myoblast differentiation revealed by transcriptional profiling. Physiol Genom 2002;10:103-11.
14. Nayernia K, Lee JH, Drusenheimer N, Nolte J, Wulf G, Dressel R et al. Derivation of male germ cells from bone marrow stem cells. Lab Invest 2006a;86:654-63.
15. Nayernia K, Nolte J, Michelmann HW, Lee JH, Rathsack K, Drusenheimer N et al. In vitro-differentiated embryonic stem cells give rise to male gametes that can generate offspring mice. Dev Cell 2006b;11:125-32.
16. Okada M, Sangadala S, Liu Y, Yoshida M, Reddy BV, Titus L et al. Development and optimization of a cell-based assay for the selection of synthetic compounds that potentiate bone morphogenetic protein-2 activity. Cell Biochem Funct 2009;27(8):526-34.
17. Oulad-Abdelghani M, Bouillet P, Decimo D, Gansmuller A, Heyberger S, Dolle P et al. Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acidresponsive gene. J Cell Biol 1996;135:469-77.
18. Pellegrini M, Grimaldi P, Rossi P, Geremia R, Dolci S. Developmental expression of BMP4/ALK3/SMAD5 signaling pathway in the mouse testis: a potential role of BMP4 in spermatogonia differentiation. J Cell Sci 2003;116:3363-72.
19. Tedesco M, La Sala G, Barbagallo F, De Felici M, Farini D. Stimulated by retinoic acid gene 8 (STRA8) shuttles between nucleus and cytoplasm and displays transcriptional activity. J Biol Chem 2009;284(51):35781-93.
20. Toyooka Y, Tsunekawa N, Takahashi Y, Matsui Y, Satoh M, Noce T. Expression and intracellular localization of mouse vasa-homologue protein during germ cell development. Mech Dev 2000;93:139-49.
21. Tremblay KD, Dunn NR, Robertson EJ. Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation. Development 2001;128:3609-21.
22. Xing W, Krishnamurthy H, Sairam MR. Role of follitropin receptor signaling in nuclear protein transitions and chromatin condensation during spermatogenesis. Biochem Biophys Res Commun 2003;312:697-701.
23. Zhou H, Jin Z, Liu J, Yu S, Cui Q, Yi D. Mesenchymal stem cells might be used to induce tolerance in heart transplantation. Med Hypotheses 2008a;70:785-7.
24. Zhou Q, Li Y, Nie R, Friel P, Mitchell D, Evanoff RM et al. Expression of stimulated by retinoic acid gene 8 (Stra8) and maturation of murine gonocytes and spermatogonia induced by retinoic acid in vitro. Biol Reprod 2008b;78:537-45.
25. Zhou Q, Nie R, Li Y, Friel P, Mitchell D, Hess RA et al. Expression of stimulated by retinoic acid gene 8 (stra8) in spermatogenic cells induced by retinoic acid: an in vivo study in vitamin A-sufficient postnatal murine testes. Biol Reprod 2008c;79(1):35-42.