CYP1, a hypovirus-regulated cyclophilin, is required for virulence in the chestnut blight fungus

Molecular Plant Pathology

Volumn 12, Issue 3, 2011, Pages 239-246

  Chen, Min Mei ^a   Jiang, Mingguo ^a   Shang, Jinjie ^a   Lan, Xiuwan ^a   Yang, Feng ^a   Huang, Jingkuan ^a   Nuss, Donald L ^b   Chen, Baoshan ^a  

^a GUANGXI UNIVERSITY   (China)

^b UNIVERSITY OF MARYLAND   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOPHILIN; FUNGAL PROTEIN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MESSENGER RNA;

AMINO ACID SEQUENCE; ARTICLE; ASCOMYCETES; CHEMISTRY; GENE DELETION; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETICS; HIPPOCASTANACEAE; METABOLISM; MICROBIOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PHENOTYPE; PLANT DISEASE; RNA VIRUS; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SOUTHERN BLOTTING; VIROLOGY; VIRULENCE;

AMINO ACID SEQUENCE; ASCOMYCOTA; BLOTTING, SOUTHERN; CLONING, MOLECULAR; CYCLOPHILINS; FUNGAL PROTEINS; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; GENE KNOCKOUT TECHNIQUES; HETEROTRIMERIC GTP-BINDING PROTEINS; HIPPOCASTANACEAE; MOLECULAR SEQUENCE DATA; PHENOTYPE; PLANT DISEASES; RNA VIRUSES; RNA, MESSENGER; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; VIRULENCE;

CRYPHONECTRIA PARASITICA; EUKARYOTA; FUNGI; HYPOVIRUS;

EID: 79952065859     PISSN: 14646722     EISSN: 13643703     Source Type: Journal    
DOI: 10.1111/j.1364-3703.2010.00665.x     Document Type: Article

References (36)

1. Anagnostakis, S.L. (1982) Biological control of chestnut blight. Science, 29, 466-471.
2. Azhderian, E.M., Kolipaka, J., Lentz, S. and Lorber, M.I. (1993) Nuclear membrane-associated cyclophilins of potential importance in cyclosporine immunosuppression. Transplant. Proc. 25, 524-526.
3. Bienkowska-Haba, M., Patel, H.D. and Sapp, M. (2009) Target cell cyclophilins facilitate human papillomavirus type 16 infection. PLoS Pathog. 5, e1000524.
4. Cardenas, M.E., Hemenway, C., Muir, R.S., Ye, R., Fiorentino, D. and Heitman, J. (1994) Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands. EMBO J. 13, 5944-5957.
5. Chen, B., Gao, S., Choi, G.H. and Nuss, D.L. (1996) Extensive alteration of fungal gene transcript accumulation and elevation of G-protein-regulated cAMP levels by a virulence-attenuating hypovirus. Proc. Natl. Acad. Sci. USA, 93, 7996-8000.
6. Choi, E.S., Chung, H.J., Kim, M.J., Park, S.M., Cha, B.J., Yang, M.S. and Kim, D.H. (2005) Characterization of the ERK homologue CpMK2 from the chestnut blight fungus Cryphonectria parasitica. Microbiology, 151, 1349-1358.
7. Choi, G.H., Chen, B. and Nuss, D.L. (1995) Virus-mediated or transgenic suppression of a G-protein alpha subunit and attenuation of fungal virulence. Proc. Natl. Acad. Sci. USA, 92, 305-309.
8. Churchill, A.C.L., Ciuffetti, L.M., Hansen, D.R., Etten, H.D. and Alfen, N.K. (1990) Transformation of the fungal pathogen Cryphonectria parasitica with a variety of heterologous plasmids. Curr. Genet. 17, 25-31.
9. Dawe, A.L., Segers, G.C., Allen, T.D., McMains, V.C. and Nuss, D.L. (2004) Microarray analysis of Cryphonectria parasitica Galpha- and Gbetagamma-signalling pathways reveals extensive modulation by hypovirus infection. Microbiology, 150, 4033-4043.
10. Deng, F., Allen, T.D. and Nuss, D.L. (2007) Ste12 transcription factor homologue CpST12 is down-regulated by hypovirus infection and required for virulence and female fertility of the chestnut blight fungus Cryphonectria parasitica. Eukaryot. Cell, 6, 235-244.
11. Fischer, G., Bang, H. and Mech, C. (1984) Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptides. Biomed. Biochim. Acta, 43, 1101-1111.
12. Gaither, L.A., Borawski, J., Anderson, L.J., Balabanis, K.A., Devay, P., Joberty, G., Rau, C., Schirle, M., Bouwmeester, T., Mickanin, C., Zhao, S., Vickers, C., Lee, L., Deng, G., Baryza, J., Fujimoto, R.A., Lin, K., Compton, T. and Wiedmann, B. (2010) Multiple cyclophilins involved in different cellular pathways mediate HCV replication. Virology, 397, 43-55.
13. Gao, S. and Nuss, D.L. (1996) Distinct roles for two G protein alpha subunits in fungal virulence, morphology, and reproduction revealed by targeted gene disruption. Proc. Natl. Acad. Sci. USA, 93, 14122-14127.
14. Gothel, S.F. and Marahiel, M.A. (1999) Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalysts. Cell. Mol. Life Sci. 55, 423-436.
15. Handschumacher, R.E., Harding, M.W., Rice, J., Drugge, R.J. and Speicher, D.W. (1984) Cyclophilin: a specific cytosolic binding protein for cyclosporin A. Science, 226, 544-547.
16. Hillman, B.I., Shapira, R. and Nuss, D.L. (1990) Hypovirulence-associated suppression of host functions in Cryphonectria parasitica can be partially relieved by high light intensity. Phytopathology, 80, 950-956. 934 ref.
17. Kim, M.J., Choi, J.W., Park, S.M., Cha, B.J., Yang, M.S. and Kim, D.H. (2002) Characterization of a fungal protein kinase from Cryphonectria parasitica and its transcriptional upregulation by hypovirus. Mol. Microbiol. 45, 933-941.
18. Kumari, S., Singh, P., Singla-Pareek, S.L. and Pareek, A. (2009) Heterologous expression of a salinity and developmentally regulated rice cyclophilin gene (OsCyp2) in E. coli and S. cerevisiae confers tolerance towards multiple abiotic stresses. Mol. Biotechnol. 42, 195-204.
19. Lan, X., Yao, Z., Zhou, Y., Shang, J., Lin, H., Nuss, D.L. and Chen, B. (2008) Deletion of the cpku80 gene in the chestnut blight fungus, Cryphonectria parasitica, enhances gene disruption efficiency. Curr. Genet. 53, 59-66.
20. Lang, K., Schmid, F.X. and Fischer, G. (1987) Catalysis of protein folding by prolyl isomerase. Nature, 329, 268-270.
21. Larson, T.G., Choi, G.H. and Nuss, D.L. (1992) Regulatory pathways governing modulation of fungal gene expression by a virulence-attenuating mycovirus. EMBO J. 11, 4539-4548.
22. Lin, H., Lan, X., Liao, H., Parsley, T.B., Nuss, D.L. and Chen, B. (2007) Genome sequence, full-length infectious cDNA clone, and mapping of viral double-stranded RNA accumulation determinant of hypovirus CHV1-EP721. J. Virol. 81, 1813-1820.
23. Liu, J., Farmer, J.D. Jr, Lane, W.S., Friedman, J., Weissman, I. and Schreiber, S.L. (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell, 66, 807-815.
24. Liu, X., Sun, L., Yu, M., Wang, Z., Xu, C., Xue, Q., Zhang, K., Ye, X., Kitamura, Y. and Liu, W. (2009b) Cyclophilin A interacts with influenza A virus M1 protein and impairs the early stage of the viral replication. Cell. Microbiol. 11, 730-741.
25. Liu, Z., Yang, F., Robotham, J.M. and Tang, H. (2009a) Critical role of cyclophilin A and its prolyl-peptidyl isomerase activity in the structure and function of the hepatitis C virus replication complex. J. Virol. 83, 6554-6565.
26. Odom, A., Muir, S., Lim, E., Toffaletti, D.L., Perfect, J. and Heitman, J. (1997) Calcineurin is required for virulence of Cryptococcus neoformans. EMBO J. 16, 2576-2589.
27. Park, S., Choi, E.S., Kim, M.J., Cha, B.J., Yang, M.S. and Kim, D.H. (2004) Characterization of HOG1 homologue, CpMK1, from Cryphonectria parasitica and evidence for hypovirus-mediated perturbation of its phosphorylation in response to hypertonic stress. Mol. Microbiol. 51, 1267-1277.
28. 2+ gradient. Mol. Gen. Genet. 256, 104-114.
29. Puhalla, J.E. and Anagnostakis, S.L. (1971) Genetics and nutritional requirements of Endothia parasitica. Phytopathology, 61, 169-173.
30. Sambrook, J. and Russell, D.W. (2001) Molecular Cloning: A Laboratory Manual. New York: Cold Spring Harbor Laboratory Press.
31. Schonbrunner, E.R., Mayer, S., Tropschug, M., Fischer, G., Takahashi, N. and Schmid, F.X. (1991) Catalysis of protein folding by cyclophilins from different species. J. Biol. Chem. 266, 3630-3635.
32. Shang, J., Wu, X., Lan, X., Fan, Y., Dong, H., Deng, Y., Nuss, D.L. and Chen, B. (2008) Large-scale expressed sequence tag analysis for the chestnut blight fungus Cryphonectria parasitica. Fungal Genet. Biol. 45, 319-327.
33. Viaud, M.C., Balhadere, P.V. and Talbot, N.J. (2002) A Magnaporthe grisea cyclophilin acts as a virulence determinant during plant infection. Plant Cell, 14, 917-930.
34. Viaud, M., Brunet-Simon, A., Brygoo, Y., Pradier, J.M. and Levis, C. (2003) Cyclophilin A and calcineurin functions investigated by gene inactivation, cyclosporin A inhibition and cDNA arrays approaches in the phytopathogenic fungus Botrytis cinerea. Mol. Microbiol. 50, 1451-1465.
35. Wang, P. and Heitman, J. (2005) The cyclophilins. Genome Biol. 6, 226.
36. Wang, P., Cardenas, M.E., Cox, G.M., Perfect, J.R. and Heitman, J. (2001) Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformans. EMBO Rep. 2, 511-518.