Prevalence, biological phenotype and genotype in moderate/mild hemophilia A with discrepancy between one-stage and chromogenic factorVIII activity

Journal of Thrombosis and Haemostasis

Volumn 9, Issue 3, 2011, Pages 524-530

  Trossaert M ^a   Boisseau, P ^a   Quemener, A ^b   Sigaud, M ^a   Fouassier, M ^a   Ternisien, C ^a   Lefrancois Bettembourg A ^a   Tesson, C ^a   Thomas, C ^a   Bezieau, S ^a  

^a NANTES UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE NANTES   (France)

Author keywords

Chromogenic factor VIII:C assay; Coagulation factor VIII; Discrepant mild hemophilia; Gene mutations

Indexed keywords

BLOOD CLOTTING FACTOR 8C; CHROMOGENIC SUBSTRATE; DNA;

ANALYTIC METHOD; ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING TEST; CHROMOGENIC ASSAY; GENOTYPE; HEMOPHILIA A; HUMAN; MAJOR CLINICAL STUDY; MISSENSE MUTATION; MUTATIONAL ANALYSIS; NUCLEOTIDE SEQUENCE; PARTIAL THROMBOPLASTIN TIME; PATHOPHYSIOLOGY; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINO ACID SUBSTITUTION; BLOOD CHEMICAL ANALYSIS; CHROMOGENIC COMPOUNDS; CONSERVED SEQUENCE; DNA MUTATIONAL ANALYSIS; FACTOR VIII; FRANCE; GENETIC ASSOCIATION STUDIES; HEMOPHILIA A; HUMANS; MALE; MODELS, MOLECULAR; MUTATION, MISSENSE; PROTEIN STRUCTURE, TERTIARY;

EID: 79952045233     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2010.04174.x     Document Type: Article

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