Localized bimodal response of neurite extensions and structural proteins in dorsal-root ganglion neurons with controlled polydimethylsiloxane substrate stiffness

Journal of Biomechanics

Volumn 44, Issue 5, 2011, Pages 856-862

  Cheng, Chao Min ^a,b   LeDuc, Philip R ^a   Lin, Yi Wen ^c  

^a CARNEGIE MELLON UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Actin; Cell adhesion; Dorsal root ganglia; Elasticity; Polydimethylsiloxane

Indexed keywords

ACTIN; ACTIN FILAMENT; CELL DENSITY; CELLULAR MORPHOLOGY; CO-CULTURES; CURING AGENTS; DORSAL ROOT GANGLIA; EXTRACELLULAR MATRIX MOLECULES; GLIAL CELLS; GROWTH FACTOR; IN-FIELD; MATERIAL INTERACTIONS; MATERIAL INTERFACES; MICROTUBULES; NEURAL RESPONSE; NEURITE EXTENSION; NEURITE OUTGROWTH; NEUROFILAMENTS; PHYSICAL PARAMETERS; POLYDIMETHYLSILOXANE PDMS; SEMI-RIGID; STRUCTURAL ELEMENTS; STRUCTURAL PROTEINS; SURFACE RIGIDITY; TISSUE STIFFNESS;

ADHESION; BIOLOGICAL MATERIALS; BIOMECHANICS; CELL ADHESION; CELL CULTURE; ELASTICITY; MECHANICAL PROPERTIES; MICROCHANNELS; MORPHOLOGY; NEURONS; PHYSIOLOGICAL MODELS; PROTEINS; SILICONES; STIFFNESS;

SUBSTRATES;

DIMETICONE; MICROTUBULE ASSOCIATED PROTEIN 2; STRUCTURAL PROTEIN;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DENSITY; CELL STRUCTURE; CELLULAR DISTRIBUTION; COCULTURE; CONTROLLED STUDY; CULTURE MEDIUM; ELASTICITY; GLIA CELL; MICROTUBULE; MOUSE; NERVE CELL GROWTH; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; RIGIDITY; SPINAL GANGLION;

ACTINS; ANIMALS; CELL ADHESION; COCULTURE TECHNIQUES; DIMETHYLPOLYSILOXANES; GANGLIA, SPINAL; MICE; MICROSCOPY, FLUORESCENCE; MICROTUBULES; NEURITES; NEUROFILAMENT PROTEINS; NEUROGLIA; NEURONS; TIME FACTORS; TISSUE ENGINEERING;

EID: 79952043099     PISSN: 00219290     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2010.12.006     Document Type: Article

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