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Volumn 48, Issue 4, 2011, Pages 456-464

Functional analysis of a mitochondrial phosphopantetheinyl transferase (PPTase) gene pptB in Aspergillus fumigatus

Author keywords

Aspergillus fumigatus; Essential genes; NpgA; Phosphopantetheinyl transferase; PptA; PptB; Respiration; Siderophore

Indexed keywords

ACYL CARRIER PROTEIN A; FUNGAL PROTEIN; IRON; LYSINE; UNCLASSIFIED DRUG;

EID: 79952036359     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2010.12.006     Document Type: Article
Times cited : (24)

References (37)
  • 1
    • 0022195719 scopus 로고
    • Development of a high-frequency transforming vector for Aspergillus nidulans
    • Ballance D.J., Turner G. Development of a high-frequency transforming vector for Aspergillus nidulans. Gene 1985, 36:321-331.
    • (1985) Gene , vol.36 , pp. 321-331
    • Ballance, D.J.1    Turner, G.2
  • 2
    • 0030925929 scopus 로고    scopus 로고
    • Mitochondrial acyl carrier protein is involved in lipoic acid synthesis in Saccharomyces cerevisiae
    • Brody S., Oh C.K., Hoja U., Schweizer E. Mitochondrial acyl carrier protein is involved in lipoic acid synthesis in Saccharomyces cerevisiae. FEBS Letters 1997, 408:217-220.
    • (1997) FEBS Letters , vol.408 , pp. 217-220
    • Brody, S.1    Oh, C.K.2    Hoja, U.3    Schweizer, E.4
  • 4
    • 77649305693 scopus 로고    scopus 로고
    • The Transposon impala is activated by low temperatures: use of a controlled transposition system to identify genes critical for viability of Aspergillus fumigatus
    • Carr P.D., Tuckwell D., Hey P.M., Simon L., d'Enfert C., Birch M., Oliver J.D., Bromley M.J. The Transposon impala is activated by low temperatures: use of a controlled transposition system to identify genes critical for viability of Aspergillus fumigatus. Eukaryotic Cell 2010, 9:438-448.
    • (2010) Eukaryotic Cell , vol.9 , pp. 438-448
    • Carr, P.D.1    Tuckwell, D.2    Hey, P.M.3    Simon, L.4    d'Enfert, C.5    Birch, M.6    Oliver, J.D.7    Bromley, M.J.8
  • 5
    • 0029915525 scopus 로고    scopus 로고
    • Computational method to predict mitochondrially imported proteins and their targeting sequences
    • Claros M.G., Vincens P. Computational method to predict mitochondrially imported proteins and their targeting sequences. European Journal of Biochemistry 1996, 241:779-786.
    • (1996) European Journal of Biochemistry , vol.241 , pp. 779-786
    • Claros, M.G.1    Vincens, P.2
  • 6
    • 48649095210 scopus 로고    scopus 로고
    • Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases
    • Crawford J.M., Vagstad A.L., Ehrlich K.C., Udwary D.W., Townsend C.A. Acyl-carrier protein-phosphopantetheinyltransferase partnerships in fungal fatty acid synthases. ChemBioChem 2008, 9:1559-1563.
    • (2008) ChemBioChem , vol.9 , pp. 1559-1563
    • Crawford, J.M.1    Vagstad, A.L.2    Ehrlich, K.C.3    Udwary, D.W.4    Townsend, C.A.5
  • 8
    • 77952547165 scopus 로고    scopus 로고
    • Therapy for fungal diseases: opportunities and priorities
    • Denning D.W., Hope W.W. Therapy for fungal diseases: opportunities and priorities. Trends in Microbiology 2010, 18:195-204.
    • (2010) Trends in Microbiology , vol.18 , pp. 195-204
    • Denning, D.W.1    Hope, W.W.2
  • 9
    • 0033545834 scopus 로고    scopus 로고
    • Lysine biosynthesis in Saccharomyces cerevisiae: Mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5
    • Ehmann D.E., Gehring A.M., Walsh C.T. Lysine biosynthesis in Saccharomyces cerevisiae: Mechanism of alpha-aminoadipate reductase (Lys2) involves posttranslational phosphopantetheinylation by Lys5. Biochemistry 1999, 38:6171-6177.
    • (1999) Biochemistry , vol.38 , pp. 6171-6177
    • Ehmann, D.E.1    Gehring, A.M.2    Walsh, C.T.3
  • 10
    • 0034111426 scopus 로고    scopus 로고
    • A novel function of yeast fatty acid synthase - subunit alpha is capable of self-pantetheinylation
    • Fichtlscherer F., Wellein C., Mittag M., Schweizer E. A novel function of yeast fatty acid synthase - subunit alpha is capable of self-pantetheinylation. European Journal of Biochemistry 2000, 267:2666-2671.
    • (2000) European Journal of Biochemistry , vol.267 , pp. 2666-2671
    • Fichtlscherer, F.1    Wellein, C.2    Mittag, M.3    Schweizer, E.4
  • 11
    • 70449700021 scopus 로고    scopus 로고
    • Phosphopantetheinyl transferase inhibition and secondary metabolism
    • Foley T.L., Young B.S., Burkart M.D. Phosphopantetheinyl transferase inhibition and secondary metabolism. FEBS Journal 2009, 276:7134-7145.
    • (2009) FEBS Journal , vol.276 , pp. 7134-7145
    • Foley, T.L.1    Young, B.S.2    Burkart, M.D.3
  • 13
    • 0041707673 scopus 로고    scopus 로고
    • Molecular characterization of the Candida albicans LYS5 gene and site-directed mutational analysis of the PPTase (Lys5p) domains for lysine biosynthesis
    • Guo S.J., Bhattacharjee J.K. Molecular characterization of the Candida albicans LYS5 gene and site-directed mutational analysis of the PPTase (Lys5p) domains for lysine biosynthesis. FEMS Microbiology Letters 2003, 224:261-267.
    • (2003) FEMS Microbiology Letters , vol.224 , pp. 261-267
    • Guo, S.J.1    Bhattacharjee, J.K.2
  • 14
    • 71849088941 scopus 로고    scopus 로고
    • Mitochondrial fatty acid synthesis - an adopted set of enzymes making a pathway of major importance for the cellular metabolism
    • Hiltunen J.K., Chen Z., Haapalainen A.M., Wierenga R.K., Kastaniotis A.J. Mitochondrial fatty acid synthesis - an adopted set of enzymes making a pathway of major importance for the cellular metabolism. Progress in Lipid Research 2010, 49:27-45.
    • (2010) Progress in Lipid Research , vol.49 , pp. 27-45
    • Hiltunen, J.K.1    Chen, Z.2    Haapalainen, A.M.3    Wierenga, R.K.4    Kastaniotis, A.J.5
  • 18
    • 0042858246 scopus 로고    scopus 로고
    • Cloning, expression, and characterization of a human 4'-phosphopantetheinyl transferase with broad substrate specificity
    • Joshi A.K., Zhang L., Rangan V.S., Smith S. Cloning, expression, and characterization of a human 4'-phosphopantetheinyl transferase with broad substrate specificity. Journal of Biological Chemistry 2003, 278:33142-33149.
    • (2003) Journal of Biological Chemistry , vol.278 , pp. 33142-33149
    • Joshi, A.K.1    Zhang, L.2    Rangan, V.S.3    Smith, S.4
  • 19
    • 0038112130 scopus 로고    scopus 로고
    • The npgA/cfwA gene encodes a putative 4'-phosphopantetheinyl transferase which is essential for penicillin biosynthesis in Aspergillus nidulans
    • Keszenman-Pereyra D., Lawrence S., Twfieg M.E., Price J., Turner G. The npgA/cfwA gene encodes a putative 4'-phosphopantetheinyl transferase which is essential for penicillin biosynthesis in Aspergillus nidulans. Current Genetics 2003, 43:186-190.
    • (2003) Current Genetics , vol.43 , pp. 186-190
    • Keszenman-Pereyra, D.1    Lawrence, S.2    Twfieg, M.E.3    Price, J.4    Turner, G.5
  • 22
    • 0031730240 scopus 로고    scopus 로고
    • Identification of a polyketide synthase gene (pksP) of Aspergillus fumigatus involved in conidial pigment biosynthesis and virulence
    • Langfelder K., Jahn B., Gehringer H., Schmidt A., Wanner G., Brakhage A.A. Identification of a polyketide synthase gene (pksP) of Aspergillus fumigatus involved in conidial pigment biosynthesis and virulence. Medical Microbiology and Immunology 1998, 187:79-89.
    • (1998) Medical Microbiology and Immunology , vol.187 , pp. 79-89
    • Langfelder, K.1    Jahn, B.2    Gehringer, H.3    Schmidt, A.4    Wanner, G.5    Brakhage, A.A.6
  • 24
    • 20444441668 scopus 로고    scopus 로고
    • A 4'-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus
    • Neville C., Murphy A., Kavanagh K., Doyle S. A 4'-phosphopantetheinyl transferase mediates non-ribosomal peptide synthetase activation in Aspergillus fumigatus. ChemBioChem 2005, 6:679-685.
    • (2005) ChemBioChem , vol.6 , pp. 679-685
    • Neville, C.1    Murphy, A.2    Kavanagh, K.3    Doyle, S.4
  • 26
    • 0346882884 scopus 로고    scopus 로고
    • 4'-Phosphopantetheinyl transferase-encoding npgA is essential for siderophore biosynthesis in Aspergillus nidulans
    • Oberegger H., Eisendle M., Schrettl M., Graessle S., Haas H. 4'-Phosphopantetheinyl transferase-encoding npgA is essential for siderophore biosynthesis in Aspergillus nidulans. Current Genetics 2003, 44:211-215.
    • (2003) Current Genetics , vol.44 , pp. 211-215
    • Oberegger, H.1    Eisendle, M.2    Schrettl, M.3    Graessle, S.4    Haas, H.5
  • 27
    • 0042971415 scopus 로고    scopus 로고
    • TINA interacts with the NIMA kinase in Aspergillus nidulans and negatively regulates astral microtubules during metaphase arrest
    • Osmani A.H., Davies J., Oakley C.E., Oakley B.R., Osmani S.A. TINA interacts with the NIMA kinase in Aspergillus nidulans and negatively regulates astral microtubules during metaphase arrest. Molecular Biology of the Cell 2003, 14:3169-3179.
    • (2003) Molecular Biology of the Cell , vol.14 , pp. 3169-3179
    • Osmani, A.H.1    Davies, J.2    Oakley, C.E.3    Oakley, B.R.4    Osmani, S.A.5
  • 28
    • 48349101984 scopus 로고    scopus 로고
    • Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process
    • Remacle C., Barbieri M.R., Cardol P., Hamel P.P. Eukaryotic complex I: functional diversity and experimental systems to unravel the assembly process. Molecular Genetics and Genomics 2008, 280:93-110.
    • (2008) Molecular Genetics and Genomics , vol.280 , pp. 93-110
    • Remacle, C.1    Barbieri, M.R.2    Cardol, P.3    Hamel, P.P.4
  • 29
    • 0141516267 scopus 로고    scopus 로고
    • The Aspergillus nidulans alcA promoter drives tightly regulated conditional gene expression in Aspergillus fumigatus permitting validation of essential genes in this human pathogen
    • Romero B., Turner G., Olivas I., Laborda F., De Lucas J.R. The Aspergillus nidulans alcA promoter drives tightly regulated conditional gene expression in Aspergillus fumigatus permitting validation of essential genes in this human pathogen. Fungal Genetics and Biology 2003, 40:103-114.
    • (2003) Fungal Genetics and Biology , vol.40 , pp. 103-114
    • Romero, B.1    Turner, G.2    Olivas, I.3    Laborda, F.4    De Lucas, J.R.5
  • 31
    • 0029556942 scopus 로고
    • Different respiratory defective phenotypes of Neurospora crassa and Saccharomyces cerevisiae after inactivation of the gene encoding the mitochondrial acyl carrier protein
    • Schneider R., Massow M., Lisowsky T., Weiss H. Different respiratory defective phenotypes of Neurospora crassa and Saccharomyces cerevisiae after inactivation of the gene encoding the mitochondrial acyl carrier protein. Current Genetics 1995, 29:10-17.
    • (1995) Current Genetics , vol.29 , pp. 10-17
    • Schneider, R.1    Massow, M.2    Lisowsky, T.3    Weiss, H.4
  • 33
    • 0032575508 scopus 로고    scopus 로고
    • A novel phosphopantetheine: protein transferase activating yeast mitochondrial acyl carrier protein
    • Stuible H.P., Meier S., Wagner C., Hannappel E., Schweizer E. A novel phosphopantetheine: protein transferase activating yeast mitochondrial acyl carrier protein. Journal of Biological Chemistry 1998, 273:22334-22339.
    • (1998) Journal of Biological Chemistry , vol.273 , pp. 22334-22339
    • Stuible, H.P.1    Meier, S.2    Wagner, C.3    Hannappel, E.4    Schweizer, E.5
  • 35
    • 0347717823 scopus 로고    scopus 로고
    • Identification of a phosphopantetheinyl transferase for erythromycin biosynthesis in Saccharopolyspora erythraea
    • Weissman K.J., Hong H., Oliynyk M., Siskos A.P., Leadlay P.F. Identification of a phosphopantetheinyl transferase for erythromycin biosynthesis in Saccharopolyspora erythraea. ChemBioChem 2004, 5:116-125.
    • (2004) ChemBioChem , vol.5 , pp. 116-125
    • Weissman, K.J.1    Hong, H.2    Oliynyk, M.3    Siskos, A.P.4    Leadlay, P.F.5
  • 36
    • 6344277118 scopus 로고    scopus 로고
    • Rapid production of gene replacement constructs and generation of a green fluorescent protein-tagged centromeric marker in Aspergillus nidulans
    • Yang L., Ukil L., Osmani A., Nahm F., Davies J., De Souza C.P.C., Dou X.W., Perez-Balaguer A., Osmani S.A. Rapid production of gene replacement constructs and generation of a green fluorescent protein-tagged centromeric marker in Aspergillus nidulans. Eukaryotic Cell 2004, 3:1359-1362.
    • (2004) Eukaryotic Cell , vol.3 , pp. 1359-1362
    • Yang, L.1    Ukil, L.2    Osmani, A.3    Nahm, F.4    Davies, J.5    De Souza, C.P.C.6    Dou, X.W.7    Perez-Balaguer, A.8    Osmani, S.A.9
  • 37
    • 75749140876 scopus 로고    scopus 로고
    • A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase
    • Yasgar A., Foley T.L., Jadhav A., Inglese J., Burkart M.D., Simeonov A. A strategy to discover inhibitors of Bacillus subtilis surfactin-type phosphopantetheinyl transferase. Molecular Biosystems 2010, 6:365-375.
    • (2010) Molecular Biosystems , vol.6 , pp. 365-375
    • Yasgar, A.1    Foley, T.L.2    Jadhav, A.3    Inglese, J.4    Burkart, M.D.5    Simeonov, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.