Shear-mediated platelet adhesion analysis in less than 100 μL of blood: Toward a POC platelet diagnostic

IEEE Transactions on Biomedical Engineering

Volumn 58, Issue 3 PART 2, 2011, Pages 826-830

  Kent, Nigel J ^a,b   O'Brien, Sinead ^c   Basabe Desmonts, Lourdes ^c   Meade, Gerardene R ^c   MacCraith, Brian D ^a   Corcoran, Brian G ^d   Kenny, Dermot ^c   Ricco, Antonio J ^d  

^a Biomedical Diagnostics Institute   (Ireland)

^b DUBLIN INSTITUTE OF TECHNOLOGY   (Ireland)

^c ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^d DUBLIN CITY UNIVERSITY   (Ireland)

Author keywords

Cell surface interactions; hydrodynamic focusing; image analysis; lab on a chip device; microfluidics; platelet assay; point of care diagnostics

Indexed keywords

AGGREGATE SIZE DISTRIBUTIONS; AQUEOUS BUFFER; CELL-SURFACE INTERACTIONS; DEVICE DESIGN; DISEASE STATE; FLOW ANALYSIS; FLOW-TIME; FLUID STREAMS; FLUORESCENT LABELING; FUNCTION OF TIME; HYDRODYNAMIC FOCUSING; IMAGE ANALYSIS SOFTWARE; LAB-ON-A-CHIP DEVICE; MICROFLUIDIC CHIP; ON CHIPS; PLATELET ADHESION; POINT-OF-CARE DIAGNOSTICS; PROTEIN SURFACE; RELATIVE FLOW; SAMPLE CONSUMPTION; SAMPLE VOLUME; SHEAR CONDITIONS; SHEAR RATES; SURFACE COVERAGES; THIN FLUIDS; VON WILLEBRAND FACTOR; WALL SHEAR STRESS; WHOLE BLOOD;

AGGLOMERATION; ASSAYS; BLOOD; DIAGNOSIS; DRUG THERAPY; FLUID DYNAMICS; FLUIDS; FOCUSING; HYDRODYNAMICS; IMAGE ANALYSIS; MICROFLUIDICS; PLATELETS; SHEAR DEFORMATION;

SHEAR FLOW;

ABCIXIMAB; FLUORESCENT DYE; VON WILLEBRAND FACTOR;

AQUEOUS SOLUTION; ARTICLE; BLOOD FLOW VELOCITY; CELL ASSAY; CELL INTERACTION; CELL LABELING; CELL SURFACE; CELLULAR DISTRIBUTION; COMPUTER PROGRAM; CONTROLLED STUDY; FLOW MEASUREMENT; HUMAN; HYDRODYNAMICS; IMAGE ANALYSIS; MICROFLUIDIC ANALYSIS; MICROSCOPY; POINT OF CARE TESTING; QUANTITATIVE ANALYSIS; SHEAR FLOW; SHEAR RATE; SHEAR STRESS; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION;

BLOOD PLATELETS; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMOBILIZED PROTEINS; MICROFLUIDIC ANALYTICAL TECHNIQUES; PLATELET ADHESIVENESS; PLATELET FUNCTION TESTS; POINT-OF-CARE SYSTEMS; SHEAR STRENGTH; VON WILLEBRAND FACTOR;

EID: 79952015516     PISSN: 00189294     EISSN: None     Source Type: Journal    
DOI: 10.1109/TBME.2010.2090659     Document Type: Article

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