The reduced and altered activities of PAX5 are linked to the protein-protein interaction motif (coiled-coil domain) of the PAX5-PML fusion protein in t(9;15)-associated acute lymphocytic leukemia

Oncogene

Volumn 30, Issue 8, 2011, Pages 967-977

  Qiu, J J ^a   Chu, H ^a,b   Lu, X ^a   Jiang, X ^a,b   Dong, S ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b CENTRAL HOSPITAL OF WUHAN   (China)

Author keywords

acute lymphocytic leukemia (ALL); dimerization; FRAP; PAX5; PAX5 PML

Indexed keywords

CHIMERIC PROTEIN; TRANSCRIPTION FACTOR PAX5; TRANSCRIPTION FACTOR PAX5 PROMYELOCYTIC LEUKEMIA PROTEIN; UNCLASSIFIED DRUG;

ACUTE LYMPHOCYTIC LEUKEMIA; ARTICLE; CONTROLLED STUDY; DNA BINDING; ENZYME ACTIVITY; FEMALE; FLUORESCENCE MICROSCOPY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; REAL TIME POLYMERASE CHAIN REACTION; RETROVIRUS;

AMINO ACID MOTIFS; ANIMALS; B-CELL-SPECIFIC ACTIVATOR PROTEIN; CELL LINE; CHROMOSOMES, HUMAN, PAIR 15; CHROMOSOMES, HUMAN, PAIR 9; CONSENSUS SEQUENCE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICE; NUCLEAR PROTEINS; ONCOGENE PROTEINS, FUSION; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN TRANSPORT; RESPONSE ELEMENTS; TRANSCRIPTION FACTORS; TRANSCRIPTIONAL ACTIVATION; TRANSDUCTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

MURINAE;

EID: 79952007351     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.473     Document Type: Article

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