메뉴 건너뛰기




Volumn 27, Issue 1, 2011, Pages 29-34

Pharmacokinetic features of difluprednate ophthalmic emulsion in rabbits as determined by glucocorticoid receptor-binding bioassay

Author keywords

[No Author keywords available]

Indexed keywords

BETAMETHASONE; BETAMETHASONE SODIUM PHOSPHATE; DEXAMETHASONE; DIFLUPREDNATE; DRUG METABOLITE; FLUOROMETHOLONE; GLUCOCORTICOID RECEPTOR; PREDNISOLONE;

EID: 79951985980     PISSN: 10807683     EISSN: None     Source Type: Journal    
DOI: 10.1089/jop.2010.0106     Document Type: Article
Times cited : (24)

References (25)
  • 1
    • 0042355192 scopus 로고    scopus 로고
    • Drug-induced glaucomas: Mechanism and management
    • DOI 10.2165/00002018-200326110-00002
    • Tripathi, R.C., Tripathi, B.J., and Haggerty, C. Drug-induced glaucomas: mechanism and management. Drug Saf. 26:749-767, 2003. (Pubitemid 37056107)
    • (2003) Drug Safety , vol.26 , Issue.11 , pp. 749-767
    • Tripathi, R.C.1    Tripathi, B.J.2    Haggerty, C.3
  • 2
    • 61849137196 scopus 로고    scopus 로고
    • Search for a functional glucocorticoid receptor in the mammalian lens
    • Gupta, V., and Wagner, B.J. Search for a functional glucocorticoid receptor in the mammalian lens. Exp. Eye Res. 88:248-56, 2009.
    • (2009) Exp. Eye Res. , vol.88 , pp. 248-256
    • Gupta, V.1    Wagner, B.J.2
  • 3
    • 0016803456 scopus 로고
    • Studies on intraocular penetration and metabolism of fluorometholone in rabbits: A comparison between dexamethasone and prednisolone acetate
    • Yamauchi, H., Kito, H., and Uda, K. Studies on intraocular penetration and metabolism of fluorometholone in rabbits: a comparison between dexamethasone and prednisolone acetate. Jap. J. Ophthalmol. 19:339-345, 1975.
    • (1975) Jap. J. Ophthalmol. , vol.19 , pp. 339-345
    • Yamauchi, H.1    Kito, H.2    Uda, K.3
  • 4
    • 0023610463 scopus 로고
    • Metabolism of fluorometholone in rabbit eye
    • Akura, J. Metabolism of fluorometholone in rabbit eye. Acta Soc. Ophthalmol. Jpn. 91:1137-1146, 1987.
    • (1987) Acta Soc. Ophthalmol. Jpn. , vol.91 , pp. 1137-1146
    • Akura, J.1
  • 5
    • 79951978237 scopus 로고    scopus 로고
    • Metabolism of fluorometholone in human corneal epithelial cell line and steroidal activity of metabolite
    • Kato, M., Oda, T., Fukano, Y., et al. Metabolism of fluorometholone in human corneal epithelial cell line and steroidal activity of metabolite. J. Eye 23:391-395, 2006.
    • (2006) J. Eye , vol.23 , pp. 391-395
    • Kato, M.1    Oda, T.2    Fukano, Y.3
  • 6
    • 26944472106 scopus 로고    scopus 로고
    • Glucocorticoids; effects on gene transcription
    • Adcock, I.M., Ito K., and Barnes, P.J. Glucocorticoids; effects on gene transcription. Proc. Am. Thorac Soc. 1:247-254, 2004.
    • (2004) Proc. Am. Thorac Soc. , vol.1 , pp. 247-254
    • Adcock, I.M.1    Ito, K.2    Barnes, P.J.3
  • 7
    • 0022261398 scopus 로고
    • Anti-inflammatory activity of difluprednate, a topical anti-inflammatory steroid. I. Effects of local and subcutaneous administration
    • Takahashi, K., Arai, Y., and Kadowaki, S. Anti-inflammatory activity of difluprednate, a topical anti-inflammatory steroid (1), effect of local and subcutaneous administration. Oyo Yakuri/Pharmacometrics 29:343-353, 1985. (Pubitemid 15081683)
    • (1985) Pharmacometrics , vol.29 , Issue.3 , pp. 343-353
    • Takahashi, K.1    Arai, Y.2    Kadowaki, S.3
  • 8
    • 0022254406 scopus 로고
    • Anti-inflammatory activity of difluprednate, a topical anti-inflammatory steroid (2), effect of topical application of difluprednate ointment (DFBA)
    • Takahashi, K., Kadowaki, S., Arai, Y., and Sugasawa, K. Anti-inflammatory activity of difluprednate, a topical anti-inflammatory steroid (2), effect of topical application of difluprednate ointment (DFBA). Oyo Yakuri/Pharmacometrics 29:355-362, 1985.
    • (1985) Oyo Yakuri/Pharmacometrics , vol.29 , pp. 355-362
    • Takahashi, K.1    Kadowaki, S.2    Arai, Y.3    Sugasawa, K.4
  • 9
    • 0018250151 scopus 로고
    • Pharmacological study of a new anti-inflammatory steroid, difluprednate (CM 9155)
    • Navarro, J., Girard, J., Lacour, C., Unkovic, J., and Lafille, C. Pharmacological study of a new anti-inflammatory steroid, difluprednate (CM 9155). Arzneimittelforschung 28:2302-2311, 1978. (Pubitemid 9093238)
    • (1978) Arzneimittel-Forschung/Drug Research , vol.28 , Issue.12 , pp. 2302-2311
    • Navarro, J.1    Girard, J.2    Lacour, C.3
  • 10
    • 0021803013 scopus 로고
    • Studies on the metabolic fate of difluprednate (DFBA) (1) absorption distribution and excretion after subcutaneous administration to rats and rabbits
    • Fujino, A., Ohta, S., Shinozawa, N., et al. Studies on the metabolic fate of difluprednate (DFBA) (1): absorption, distribution and excretion after subcutaneous administration to rats and rabbits. Oyo Yakuri/Pharmacometrics 29:687-699, 1985. (Pubitemid 15066432)
    • (1985) Pharmacometrics , vol.29 , Issue.5 , pp. 687-699
    • Fujino, A.1    Ohta, S.2    Shinozawa, N.3
  • 11
    • 0021801470 scopus 로고
    • Studies on the metabolic fate of difluprednate (DFBA) (2) absorption, distribution and excretion after dermal application to rats and rabbits
    • Fujino, A., Ohta, S., Shinozawa, N., et al. Studies on the metabolic fate of difluprenate (DFBA) (2): absorption, distribution and excretion after dermal application to rats and rabbits. Oyo Yakuri/Pharmacometrics 29:701-712, 1985. (Pubitemid 15066433)
    • (1985) Pharmacometrics , vol.29 , Issue.5 , pp. 701-712
    • Fujino, A.1    Ohta, S.2    Shinozawa, N.3
  • 12
    • 0021889252 scopus 로고
    • Studies on the metabolic fate of difluprednate (DFBA) (3) metabolism in rats and rabbits after subcutaneous administration
    • Fujino, A., Ohta, S., Shibata, K., et al. Studies on the metabolic fate of difluprednate (DFBA) (3): metabolism in rats and rabbits after subcutaneous administration. Oyo Yakuri/Pharmacometrics 29:713-723, 1985. (Pubitemid 15066434)
    • (1985) Pharmacometrics , vol.29 , Issue.5 , pp. 713-723
    • Fujino, A.1    Ohta, S.2    Shibata, K.3
  • 14
    • 23944453408 scopus 로고    scopus 로고
    • Formulation of an ophthalmic lipid emulsion containing an anti-inflammatory steroidal drug, difluprednate
    • Yamaguchi, M., Yasueda, S., Isowaki, A., et al. Formulation of an ophthalmic lipid emulsion containing an anti-inflammatory steroidal drug, difluprednate. Int. J. Pharm. 301:121-128, 2005.
    • (2005) Int. J. Pharm. , vol.301 , pp. 121-128
    • Yamaguchi, M.1    Yasueda, S.2    Isowaki, A.3
  • 15
    • 77953437646 scopus 로고    scopus 로고
    • The role of difluprednate ophthalmic emulsion in clinical practice
    • Jamal, K.N., and Callanan, D.G. The role of difluprednate ophthalmic emulsion in clinical practice. Clin. Ophthalmol. 3:381-390, 2009.
    • (2009) Clin. Ophthalmol. , vol.3 , pp. 381-390
    • Jamal, K.N.1    Callanan, D.G.2
  • 16
    • 77954650674 scopus 로고    scopus 로고
    • Metabolic profiles of difluprednate in rabbit ocular tissues after instillation of difluprednate ophthalmic emulsion
    • Tajika, T., Takahashi, H., Sakai, Y., Fujii, H., Isowaki, A., and Sakaki, H. Metabolic profiles of difluprednate in rabbit ocular tissues after instillation of difluprednate ophthalmic emulsion. Xenobiotica 40:569-577, 2010.
    • (2010) Xenobiotica , vol.40 , pp. 569-577
    • Tajika, T.1    Takahashi, H.2    Sakai, Y.3    Fujii, H.4    Isowaki, A.5    Sakaki, H.6
  • 17
    • 79951971348 scopus 로고    scopus 로고
    • Method of AUC estimation from sparse sampling data
    • Kasai, H., Hashimoto, T., Yamada, M., et al. Method of AUC estimation from sparse sampling data. Xenobio. Metabol. Dispos. 16:253-257, 2001.
    • (2001) Xenobio. Metabol. Dispos. , vol.16 , pp. 253-257
    • Kasai, H.1    Hashimoto, T.2    Yamada, M.3
  • 18
    • 79952000148 scopus 로고    scopus 로고
    • Association for research in vision and ophthalmology
    • E-Abstract 2651
    • Inoue, J., et al. Association for research in vision and ophthalmology. Invest. Ophthalmol. Vis. Sci. 48:E-Abstract 2651, 2007.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48
    • Inoue, J.1
  • 19
    • 0021350520 scopus 로고
    • Correlation between chemical structure, receptor-binding, and biological activity of some novel, highly active, 16a, 17α-acetal-substituted glucocorticoids
    • Dahlberg, E., Thalen, A., Brattsand, R., et al. Correlation between chemical structure, receptor-binding, and biological activity of some novel, highly active, 16a, 17α-acetal-substituted glucocorticoids. Mol. Pharmacol. 25:70-78, 1983.
    • (1983) Mol. Pharmacol. , vol.25 , pp. 70-78
    • Dahlberg, E.1    Thalen, A.2    Brattsand, R.3
  • 20
    • 0037764882 scopus 로고    scopus 로고
    • Glucocorticoid receptor interactions with glucocorticoids: Evaluation by molecular modeling and functional analysis of glucocorticoid receptor mutants
    • DOI 10.1016/S0039-128X(03)00030-8
    • Hammer, S., Spika, I., Sippl, W., et al. Glucocorticoid receptor interactions with glucocorticoids: evaluation by molecular modeling and functional analysis of glucocorticoid receptor mutants. Steroids 68:329-339, 2003. (Pubitemid 36638244)
    • (2003) Steroids , vol.68 , Issue.4 , pp. 329-339
    • Hammer, S.1    Spika, I.2    Sippl, W.3    Jessen, G.4    Kleuser, B.5    Holtje, H.-D.6    Schafer-Korting, M.7
  • 21
    • 2642518935 scopus 로고    scopus 로고
    • Soft glucocorticoid design: Structural elements and physicochemical parameters determining receptor-binding affinity
    • Buchwald, P., and Bordor, N. Soft glucocorticoid design: structural elements and physicochemical parameters determining receptor-binding affinity. Pharmazie 59:396-404, 2004. (Pubitemid 38720350)
    • (2004) Pharmazie , vol.59 , Issue.5 , pp. 396-404
    • Buchwald, P.1    Bodor, N.2
  • 22
    • 37649006828 scopus 로고    scopus 로고
    • Glucocorticoid receptor binding: A biphasic dependence on molecular size as revealed by the bilinear LinBiExp model
    • Buchwald, P. Glucocorticoid receptor binding: a biphasic dependence on molecular size as revealed by the bilinear LinBiExp model. Steroids 73:193-208, 2008.
    • (2008) Steroids , vol.73 , pp. 193-208
    • Buchwald, P.1
  • 23
    • 79951989108 scopus 로고    scopus 로고
    • Association for research in vision and ophthalmology
    • E-Abstract 2652
    • Okumura, A., et al. Association for research in vision and ophthalmology. Invest. Ophthalmol. Vis. Sci. 48:E-Abstract 2652, 2007.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48
    • Okumura, A.1
  • 24
    • 79951977799 scopus 로고    scopus 로고
    • Association for research in vision and ophthalmology
    • E-Abstract 2653
    • Sakaki, H., et al. Association for research in vision and ophthalmology. Invest. Ophthalmol. Vis. Sci. 48:E-Abstract 2653, 2007.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48
    • Sakaki, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.