Metabolic profiles of difluprednate in rabbit ocular tissues after instillation of difluprednate ophthalmic emulsion

Xenobiotica

Volumn 40, Issue 8, 2010, Pages 569-577

  Tajika, Tetsuya ^a   Takahashi, Hiroaki ^a   Sakai, Yusuke ^a   Fujii, Hiroyuki ^a   Isowaki, Akiharu ^b   Sakaki, Hideyuki ^a  

^a SENJU PHARMACEUTICAL CO LTD   (Japan)

^b Senju USA Inc   (United States)

Author keywords

De 17 side chain glucocorticoid metabolite; Glucocorticoid activity; Ocular tissue metabolite

Indexed keywords

DEXAMETHASONE; DIFLUPREDNATE; DIFLUPREDNATE H 3; DRUG METABOLITE; GLUCOCORTICOID RECEPTOR; TRITIUM; UNCLASSIFIED DRUG; DRUG DOSAGE FORM; EYE DROPS; FLUPREDNISOLONE; GLUCOCORTICOID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; AQUEOUS HUMOR; ARTICLE; CILIARY BODY; CONTROLLED STUDY; CORNEA; DRUG INSTILLATION; DRUG RECEPTOR BINDING; DRUG STRUCTURE; EMULSION; EYE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IRIS; MALE; NONHUMAN; RABBIT; RADIOCHEMISTRY; ANALOGS AND DERIVATIVES; ANIMAL; DRUG DOSAGE FORM; METABOLISM; METABOLOME;

ORYCTOLAGUS CUNICULUS;

ANIMALS; AQUEOUS HUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CILIARY BODY; CORNEA; DOSAGE FORMS; FLUPREDNISOLONE; GLUCOCORTICOIDS; MALE; METABOLOME; OPHTHALMIC SOLUTIONS; RABBITS;

EID: 77954650674     PISSN: 00498254     EISSN: 13665928     Source Type: Journal    
DOI: 10.3109/00498254.2010.490308     Document Type: Article

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