A Bayesian method for single molecule, fluorescence burst analysis

Biomedical Optics Express

Volumn 1, Issue 4, 2010, Pages 1148-1158

  Barber, P R ^a,b   Ameer Beg, S M ^b   Pathmananthan, S ^b   Rowley, M ^b   Coolen, A C C ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BAYESIAN NETWORKS; MOLECULAR DYNAMICS; MOLECULES;

BACKGROUND DETECTION; BAYESIAN METHODS; BURST-INTEGRATED FLUORESCENCE LIFETIMES; ENSEMBLE AVERAGING; ENVIRONMENTAL CONDITIONS; FLUORESCENCE BURSTS; FLUORESCENCE LIFETIMES; MODEL SELECTION; PHYSICAL PARAMETERS; PROTEIN INTERACTION; SIGNAL AMPLITUDE; SINGLE MOLECULE;

FLUORESCENCE;

EID: 79951974735     PISSN: None     EISSN: 21567085     Source Type: Journal    
DOI: 10.1364/BOE.1.001148     Document Type: Article

References (19)

1. M. Böhmer, and J. Enderlein, "Fluorescence spectroscopy of single molecules under ambient conditions: methodology and technology, " ChemPhysChem 4(8), 792-808 (2003).
2. C. Eggeling, J. R. Fries, L. Brand, R. Günther, and C. A. Seidel, "Monitoring conformational dynamics of a single molecule by selective fluorescence spectroscopy, " Proc. Natl. Acad. Sci. U.S.A. 95(4), 1556-1561 (1998).
3. J. R. Fries, L. Brand, C. Eggeling, M. Kollner, and C. A. M. Seidel, "Quantitative Identification of Different Single Molecules by Selective Time-Resolved Confocal Fluorescence Spectroscopy, " J. Phys. Chem. A 102(33), 6601-6613 (1998).
4. R. Kühnemuth, and C. A. M. Seidel, "Principles of Single Molecule Multiparameter Fluorescence Spectroscopy, " Single Mol. 2(4), 251-254 (2001).
5. W. Becker, A. Bergmann, E. Haustein, Z. Petrasek, P. Schwille, C. Biskup, L. Kelbauskas, K. Benndorf, N. Klöcker, T. Anhut, I. Riemann, and K. König, "Fluorescence lifetime images and correlation spectra obtained by multidimensional time-correlated single photon counting, " Microsc. Res. Tech. 69(3), 186-195 (2006).
6. J. Enderlein, D. L. Robbins, W. P. Ambrose, and R. A. Keller, "Molecular Shot Noise, Burst Size Distribution, and Single-Molecule Detection in Fluid Flow: Effects of Multiple Occupancy, " J. Phys. Chem. A 102(30), 6089-6094 (1998).
7. W. Grange, P. Haas, A. Wild, M. A. Lieb, M. Calame, M. Hegner, and B. Hecht, "Detection of transient events in the presence of background noise, " J. Phys. Chem. B 112(23), 7140-7144 (2008).
8. J. Enderlein, P. M. Goodwin, A. Van Orden, W. Patrick Ambrose, R. Erdmann, and R. A. Keller, "A maximum likelihood estimator to distinguish single molecules by their fluorescence decays, " Chem. Phys. Lett. 270(5-6), 464-470 (1997).
9. E. Brooks Shera, N. K. Seitzinger, L. M. Davis, R. A. Keller, and S. A. Soper, "Detection of single fluorescent molecules, " Chem. Phys. Lett. 174(6), 553-557 (1990).
10. M. Prummer, C. G. Hubner, B. Sick, B. Hecht, A. Renn, and U. P. Wild, "Single-molecule identification by spectrally and time-resolved fluorescence detection, " Anal. Chem. 72(3), 443-447 (2000).
11. M. Prummer, B. Sick, A. Renn, and U. P. Wild, "Multiparameter microscopy and spectroscopy for single-molecule analytics, " Anal. Chem. 76(6), 1633-1640 (2004).
12. S. H. Lee, M. Jae, and R. P. Gardner, "Non-Poisson counting statistics of a hybrid G-M counter dead time model, " Nucl. Instrum. Methods Phys. Res. B 263, 46-49 (2007).
13. T. C. Voss, I. A. Demarco, and R. N. Day, "Quantitative imaging of protein interactions in the cell nucleus, " Biotechniques 38(3), 413-424 (2005).
14. H. Wallrabe, and A. Periasamy, "Imaging protein molecules using FRET and FLIM microscopy, " Curr. Opin. Biotechnol. 16(1), 19-27 (2005).
15. C. M. Bishop, Neural Networks for Pattern Recognition (Oxford University Press, Oxford, 1995).
16. W. H. Press, B. P. Flannery, S. A. Teukolsky, and W. T. Vetterling, Numerical Recipes in C: The Art of Scientific Computing (Cambridge University Press, 1992).
17. M. Parsons, J. Monypenny, S. M. Ameer-Beg, T. H. Millard, L. M. Machesky, M. Peter, M. D. Keppler, G. Schiavo, R. Watson, J. Chernoff, D. Zicha, B. Vojnovic, and T. Ng, "Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells, " Mol. Cell. Biol. 25(5), 1680-1695 (2005).
18. M. Peter, S. M. Ameer-Beg, M. K. Y. Hughes, M. D. Keppler, S. Prag, M. Marsh, B. Vojnovic, and T. Ng, "Multiphoton-FLIM quantification of the EGFP-mRFP1 FRET pair for localization of membrane receptor-kinase interactions, " Biophys. J. 88(2), 1224-1237 (2005).
19. P. R. Barber, S. M. Ameer-Beg, J. Gilbey, L. M. Carlin, M. Keppler, T. C. Ng, and B. Vojnovic, "Multiphoton time-domain fluorescence lifetime imaging microscopy: practical application to protein-protein interactions using global analysis, " J. R. Soc. Interface 6, S93-S105 (2009).