The role of insulin growth factor on atherosclerosis and endothelial function: The effect on hyperlipidemia and aging

Life Sciences

Volumn 88, Issue 9-10, 2011, Pages 425-431

  Hirai, Hisako ^a   Kanaya, Rie ^a   Maeda, Morihiko ^a   Qungfang, Ding ^a   Ina, Koichiro ^a   Hayashi, Toshio ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Atherosclerosis; Endothelial senescence; IGF binding protein 3; Insulin like growth factor 1; Nitric oxide

Indexed keywords

3 NITROTYROSINE; CYCLIC GMP; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPID; SOMATOMEDIN C;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA ATHEROSCLEROSIS; ARTICLE; ATHEROMA; CONTROLLED STUDY; EMBRYO CULTURE; ENDOTHELIUM; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; MACROPHAGE; MALE; NONHUMAN; PROTEIN EXPRESSION;

ACETYLCHOLINE; AGING; ANIMALS; AORTA, THORACIC; ATHEROSCLEROSIS; CHOLESTEROL, DIETARY; CYCLIC GMP; DRUG THERAPY, COMBINATION; ENDOTHELIUM, VASCULAR; HYPERLIPIDEMIAS; INJECTIONS, SUBCUTANEOUS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; INSULIN-LIKE GROWTH FACTOR I; LIPIDS; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RABBITS; SIGNAL TRANSDUCTION; VASODILATOR AGENTS;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 79951957340     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2010.12.021     Document Type: Article

References (24)

1. Abbas A, Grant PJ, Kearney MT. Role of IGF-1 in glucose regulation and cardiovascular disease. Expert Rev Cardiovasc Ther 2008;6:1135-49.
2. Action to Control Cardiovascular Risk in Diabetes (ACCORD) Study Group. Effects of intensive glucose lowering in type 2 diabetes. N Engl J Med 2008;358:2545-59.
3. ADVANCE Collaborative GroupPatel A, MacMahon S, Chalmers J, et al. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med 2008;358:2560-72. (Pubitemid 351831357)
4. Bayes-Genis A, Conover CA, Schwartz RS. The insulin-like growth factor axis - a review of atherosclerosis and restenosis. Circ Res 2000;86:125-30. (Pubitemid 30086171)
5. Beckmann JS, Ye YZ, Anderson PG, Chen J, Accavitti MA, Tarpey MM, et al. Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry. Biol Chem Hoppe Seyler 1994;375:81-8.
6. Butt AJ, Williams AC. IGFBP-3 and apoptosis - a license to kill? Apoptosis 2001;6:199-205.
7. Chisalita SI, Nitert MD, Arnqvist HJ. Characterization of receptors for IGF-I and insulin; evidence for hybrid insulin/IGF-I receptor in human coronary artery endothelial cells. Growth Horm IGF Res 2006;16:258-66. (Pubitemid 44313456)
8. Esaki T, Hayashi T, Muto E, Kuzuya M, Iguchi A. Expression of inducible nitric oxide synthase in T lymphocytes and macrophages of cholesterol-fed rabbits. Atherosclerosis 1997;128:39-47.
9. Hayashi T, Ignarro LJ, Fukuto JM, Chaudhuri G. Basal release of nitric oxide from aortic rings is greater in female rabbits than in male rabbits. Proc Natl Acad Sci USA 1992;89:11259-63.
10. Hayashi T, Esaki T, Muto E, Kano H, Iguchi A. Endothelium-dependent relaxation of rabbit atherosclerotic aorta was not restored by control of hyperlipidemia - the possible role of peroxynitrite. Atherosclerosis 1999;147:349-67.
11. Hayashi T, Esaki T, Muto E, Kano H, Asai Y, Thakur NK, et al. Dehydroepiandrosterone retards atherosclerosis formation through the conversion to estrogen - the possible role of nitric oxide. Arterioscler Thromb Vasc Biol 2000;20:782-92. (Pubitemid 30151694)
12. Hayashi T, Sumi D, Matsui-Hirai H, Fukatsu A, Arockia Rani PJ, et al. Sarpogrelate HCl, a selective 5-HT2A antagonist, retards the progression of atherosclerosis through a novel mechanism. Atherosclerosis 2003;168:23-31. (Pubitemid 36559597)
13. Hayashi T, Sumi D, Juliet PA, Matsui-Hirai H, Asai-Tanaka Y, Kano H, et al. Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits. Cardiovasc Res 2004;61:339-51. (Pubitemid 38091774)
14. Hayashi T, Matsui-Hirai H, Fukatsu A, Sumi D, Kano-Hayashi H, Rani PJA, et al. Selective iNOS inhibitor, ONO1714 successfully retards the development of high-cholesterol diet induced atherosclerosis by novel mechanism. Atherosclerosis 2006;187:316-24.
15. Jia G, Cheng G, Gangahar DM, Agrawal DK. Insulin-like growth factor-1 and TNF-alpha regulate autophagy through c-jun N-terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells. Immunol Cell Biol 2006;84:448-54. (Pubitemid 44286038)
16. Kawachi S, Takeda N, Sasaki A, Kokubo Y, Takami K, Sarui H, et al. Circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 are associated with early carotid atherosclerosis. Arterioscler Thromb Vasc Biol 2005;25:617-21. (Pubitemid 40315687)
17. Kurosu H, Yamamoto M, Clark JD, Pastor JV, Nandi A, Gurnani P, et al. Suppression of aging in mice by the hormone Klotho. Science 2005;309(5742):1829- 33. (Pubitemid 41325087)
18. Lee CY, Bazer FW, Etherton TD, Simmen FA. Ontogeny of insulin-like growth factors (IGF-I and IGF-II) and IGF-binding proteins in porcine serum during fetal and postnatal development. Endocrinology 1991;128:2336-44.
19. Li M, Chiu JF, Gagne J, Fukagawa NK. Age-related differences in insulin-like growth factor-1 receptor signaling regulates Akt/FOXO3a and ERK/Fos pathways in vascular smooth muscle cells. J Cell Physiol 2008;217:377-87.
20. Lipid Research Clinics Program Manual of Laboratory Operations. vol. 1, ed. 2. US Dept. of Health, Education and Welfare, Publ. No. (NIH). Washington, DC, US. Govt. Printing Office, pp. 76-628, 1982.
21. Martin RM, Gunnell D, Whitley E, Nicolaides A, Griffin M, Georgiou N, et al. Associations of insulin-like growth factor (IGF)-I, IGF-II, IGF binding protein (IGFBP)-2 and IGFBP-3 with ultrasound measures of atherosclerosis and plaque stability in an older adult population. J Clin Endocrinol Metab 2008;93:1331-8. (Pubitemid 351519729)
22. Miyauchi H, Minamino T, Tateno K, Kunieda T, Toko H, Komuro I. Akt negatively regulates the in vitro lifespan of human endothelial cells via a p53/p21-dependent pathway. EMBO J 2004;23:212-20. (Pubitemid 38165761)
23. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 1999;14(340):115-26. (Pubitemid 29054847)
24. Weiner BH, Ockene IS, Hoogasian JJ. Inhibition of atherosclerosis by cod-liver oil in a hyperlipidemic swine model. N Engl J Med 1986;315:841-5.