Activation of the extracellular signal-regulated kinases 1 and 2 (ERK1/2) is needed for the TGFβ-induced chondrogenic and osteogenic differentiation of mesenchymal stem cells

Biochemical and Biophysical Research Communications

Volumn 405, Issue 4, 2011, Pages 564-569

  Arita, Nestor A ^a   Pelaez, Daniel ^a,b   Cheung, Herman S ^a,b  

^a University of Miami College of Engineering   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Chondrogenesis; MAPK; Mesenchymal stem cells; Osteogenesis

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; AGGRECAN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; CYTOKINE; DEXAMETHASONE; MITOGEN ACTIVATED PROTEIN KINASE 1; TRANSCRIPTION FACTOR SOX9; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3;

ARTICLE; BONE DEVELOPMENT; BONE MARROW; CELL CULTURE; CELL DIFFERENTIATION; CHONDROGENESIS; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

CELLS, CULTURED; CHONDROGENESIS; ENZYME ACTIVATION; HUMANS; MESENCHYMAL STEM CELLS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; OSTEOGENESIS; PHOSPHORYLATION; RECOMBINANT PROTEINS; TRANSFORMING GROWTH FACTOR BETA3;

EID: 79951948362     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.01.068     Document Type: Article

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