Control and measurement of plasma pH in equilibrium dialysis: Influence on drug plasma protein binding

Drug Metabolism and Disposition

Volumn 39, Issue 3, 2011, Pages 551-557

  Curran, Ruth E ^a   Claxton, Christopher R J ^a   Hutchison, Laura ^a   Harradine, Paul J ^a   Martin, Iain J ^a   Littlewood, Peter ^a  

^a MSD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER; BUSPIRONE; CARBAMAZEPINE; CARBON DIOXIDE; CINOXACIN; CLOZAPINE; DIAZEPAM; DICLOFENAC; DILTIAZEM; FLUOXETINE; HALOPERIDOL; IMIPRAMINE; MIDAZOLAM; MILNACIPRAN; MIRTAZAPINE; NICARDIPINE; PAROXETINE; PROPRANOLOL; QUINIDINE; RISPERIDONE; SODIUM DIHYDROGEN PHOSPHATE; TRANYLCYPROMINE; TRIMIPRAMINE; VERAPAMIL; WARFARIN;

ARTICLE; ATMOSPHERE; BLOOD PH; DRUG PROTEIN BINDING; EQUILIBRIUM DIALYSIS; HUMAN; MOUSE; NONHUMAN; PH MEASUREMENT; PKA; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD PROTEINS; BUFFERS; CARBON DIOXIDE; DIALYSIS; DOGS; DRUG EVALUATION, PRECLINICAL; HUMANS; HYDROGEN-ION CONCENTRATION; MACACA FASCICULARIS; MICE; OSMOLAR CONCENTRATION; PHARMACEUTICAL PREPARATIONS; PHYSICOCHEMICAL PHENOMENA; PROTEIN BINDING; RATS; REPRODUCIBILITY OF RESULTS;

EID: 79951913810     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.110.036988     Document Type: Article

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