Investigation of the initiation site and propagation of epileptiform discharges in hippocampal slices using microelectrode array

Progress in Biochemistry and Biophysics

Volumn 37, Issue 11, 2010, Pages 1240-1247

  Gong, Xin Wei ^a   Yang, Fan ^b   Liu, Jian Sheng ^b   Lu, Qin Chi ^b   Gong, Hai Qing ^a   Liang, Pei Ji ^a   Zhang, Pu Ming ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Epileptiform discharges; Hippocampal slice; Low Mg2+ epileptic model; Microelectrode array

Indexed keywords

RATTUS;

EID: 79951906550     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2010.00065     Document Type: Article

References (13)

1. McCormick D A, Contreras D. On the cellular and network bases of epileptic seizures. Annu Rev Physiol, 2001, 63: 815-846 (Pubitemid 32304338)
2. Andersen P, Bliss T, Skrede K. Lamellar organization of hippocampal excitatory pathways. Exp Brain Res, 1971, 13(2): 222-238
3. Dzhala V I, Staley K J. Transition from interictal to ictal activity in limbic networks in vitro. J Neurosci, 2003, 23(21): 7873-7880 (Pubitemid 37052355)
4. Colom L V, Saggau P. Spontaneous interictal-like activity originates in multiple areas of the CA2-CA3 region of hippocampal slices. J Neurophysiol, 1994, 71(4): 1574-1585 (Pubitemid 24121851)
5. Hill A J, Jones N A, Williams C M, et al. Development of multi-electrode array screening for anticonvulsants in acute rat brain slices. J Neurosci Methods, 2010, 185(2): 246-256
6. 2+ -induced epileptiform activity in the intact corticohippocampal formation of the newborn mouse in vitro. Brain Res, 2006, 1077(1): 170-177
7. 2+ induced epileptiform activity in rat hippocampal and entorhinal cortex slices during adolescence. Dev Brain Res, 1995, 87(2): 145-152
8. Kass R, Ventura V, Cai C. Statistical smoothing of neuronal data. Network: Comput Neural Syst, 2003, 14(1): 5-16
9. Wittner L, Miles R. Factors defining a pacemaker region for synchrony in the hippocampus. J Physiol (Lond), 2007, 584 (3): 867-883 (Pubitemid 350031928)
10. Andersen P, Morris R, Amaral D, et al. The Hippocampus Book. New York: Oxford University Press, 2007: 9-36
11. Derchansky M, Rokni D, Rick J T, et al. Bidirectional multisite seizure propagation in the intact isolated hippocampus: The multifocality of the seizure "focus". Neurobiol Dis, 2006, 23 (2): 312-328 (Pubitemid 44080842)
12. Cohen I, Miles R. Contributions of intrinsic and synaptic activities to the generation of neuronal discharges in in vitro hippocampus. The Journal of Physiology, 2000, 524(2): 485-502 (Pubitemid 30229513)
13. Holsheimer J, Lopes S. Propagation velocity of epileptiform activity in the hippocampus. Experimental Brain Research, 1989, 77 (1): 69-78 (Pubitemid 19220538)