Requirement for asparagine in the aquaporin NPA sequence signature motifs for cation exclusion

FEBS Journal

Volumn 278, Issue 5, 2011, Pages 740-748

  Wree, Dorothea ^a   Wu, Binghua ^a   Zeuthen, Thomas ^b   Beitz, Eric ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

aquaglyceroporin; aquaporin; potassium; proton; sodium

Indexed keywords

AQUAGLYCEROPORIN; AQUAPORIN; ARGININE; ASPARAGINE; GLYCEROL; METHYLAMINE; POTASSIUM ION; PROTON; SERINE; SODIUM ION; WATER;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BURKHOLDERIA CENOCEPACIA; CHANNEL GATING; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; ION PERMEABILITY; MOLECULAR CLONING; MUTATIONAL ANALYSIS; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN STRUCTURE; WATER PERMEABILITY; XENOPUS;

AMINO ACID MOTIFS; ANIMALS; AQUAGLYCEROPORINS; AQUAPORINS; ASPARAGINE; BLOTTING, WESTERN; BURKHOLDERIA CENOCEPACIA; CATIONS; ELECTROPHYSIOLOGY; GLYCEROL; METHYLAMINES; POTASSIUM; STRUCTURE-ACTIVITY RELATIONSHIP; WATER; XENOPUS;

BURKHOLDERIA CENOCEPACIA; MAMMALIA;

EID: 79951898533     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2010.07993.x     Document Type: Article

References (31)

1. Walz T, Fujiyoshi Y, &, Engel A, (2009) The AQP structure and functional implications. Handb Exp Pharmacol 190, 31-56.
2. Beitz E, Wu B, Holm LM, Schultz JE, &, Zeuthen T, (2006) Point mutations in the aromatic/arginine region in aquaporin 1 allow passage of urea, glycerol, ammonia, and protons. Proc Natl Acad Sci USA 103, 269-274. (Pubitemid 43122390)
3. Chen H, Wu Y, &, Voth GA, (2006) Origins of proton transport behavior from selectivity domain mutations of the aquaporin-1 channel. Biophys J 90, L73-L75.
4. Hub JS, &, de Groot BL, (2008) Mechanism of selectivity in aquaporins and aquaglyceroporins. Proc Natl Acad Sci USA 105, 1198-11203.
5. Wu B, Steinbronn C, Alsterfjord M, Zeuthen T, &, Beitz E, (2009) Concerted action of two cation filters in the aquaporin water channel. EMBO J 28, 2188-2194.
6. Chen H, Ilan B, Wu Y, Zhu F, Schulten K, &, Voth GA, (2007) Charge delocalization in proton channels, I: the aquaporin channels and proton blockage. Biophys J 92, 46-60. (Pubitemid 46048415)
7. Hansen M, Kun JFJ, Schultz JE, &, Beitz E, (2002) A single, bi-functional aquaglyceroporin in blood-stage Plasmodium falciparum malaria parasites. J Biol Chem 277, 4874-4882. (Pubitemid 34968523)
8. Uzcategui NL, Szallies A, Pavlovic-Djuranovic S, Palmada M, Figarella K, Boehmer C, Lang F, Beitz E, &, Duszenko M, (2004) Cloning, heterologous expression, and characterization of three aquaglyceroporins from Trypanosoma brucei. J Biol Chem 279, 42669-42676. (Pubitemid 39372152)
9. Beitz E, (2005) Aquaporins from pathogenic protozoan parasites: structure, function and potential for chemotherapy. Biol Cell 97, 373-383. (Pubitemid 40872346)
10. Zardoya R, (2005) Phylogeny and evolution of the major intrinsic protein family. Biol Cell 97, 397-414. (Pubitemid 40872348)
11. Ishibashi K, Koike S, Kondo S, Hara S, &, Tanaka Y, (2009) The role of a group III AQP, AQP11 in intracellular organelle homeostasis. J Med Invest 56, 312-317.
12. Holden MTG, Seth-Smith HMB, Crossman LC, Sebaihia M, Bentley SD, Cerdeño-Tárraga AM, Thomson NR, Bason N, Quail MA, Sharp S, et al. (2009) The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of cystic fibrosis patients. J Bacteriol 191, 261-277.
13. Fu D, Libson A, Miercke LJ, Weitzman C, Nollert P, Krucinski J, &, Stroud RM, (2000) Structure of a glycerol-conducting channel and the basis for its selectivity. Science 290, 481-486.
14. Pruitt KD, Tatusova T, &, Maglott DR, (2007) NCBI Reference Sequences: current status, policy and new initiatives. Nucleic Acids Res 35, D61-D65.
15. Schneider TD, &, Stephens RM, (1990) Sequence logos: a new way to display consensus sequences. Nucleic Acids Res 18, 6097-6100.
16. Beitz E, (2006) Subfamily logos: visualization of sequence deviations at alignment positions with high information content. BMC Bioinformatics 21, 313.
17. Lagrée V, Froger A, Deschamps S, Hubert JF, Delamarche C, Bonnec G, Thomas D, Gouranton J, &, Pellerin I, (1999) Switch from an aquaporin to a glycerol channel by two amino acids substitution. J Biol Chem 274, 6817-6819.
18. Jung JS, Preston GM, Smith BL, Guggino WB, &, Agre P, (1994) Molecular structure of the water channel through aquaporin CHIP. The hourglass model. J Biol Chem 269, 14648-14654.
19. Chrétien S, &, de Figueiredo M, (1999) A single mutation inside the NPA motif of aquaporin-1 found in a Colton-null phenotype. Blood 93, 4021-4023. (Pubitemid 29249854)
20. Luyten K, Albertyn J, Skibbe WF, Prior BA, Ramos J, Thevelein JM, &, Hohmann S, (1995) Fps1, a yeast member of the MIP family of channel proteins, is a facilitator for glycerol uptake and efflux and is inactive under osmotic stress. EMBO J 14, 1360-1371.
21. Preston GM, Carroll TP, Guggino WB, &, Agre P, (1992) Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science 256, 385-387.
22. Borgnia MJ, &, Agre P, (2001) Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli. Proc Natl Acad Sci USA 98, 2888-2893. (Pubitemid 32209579)
23. Marini AM, Vissers S, Urrestarazu A, &, André B, (1994) Cloning and expression of the MEP1 gene encoding an ammonium transporter in Saccharomyces cerevisiae. EMBO J 13, 3456-3463. (Pubitemid 24246181)
24. Richardson JS, &, Richardson DC, (1988) Amino acid preferences for specific locations at the ends of alpha helices. Science 240, 1648-1652.
25. Serrano L, &, Fersht AR, (1989) Capping and alpha-helix stability. Nature 342, 296-299.
26. Doig AJ, MacArthur MW, Stapley BJ, &, Thornton JM, (1997) Structures of N-termini of helices in proteins. Protein Sci 6, 147-155. (Pubitemid 27045254)
27. Aurora R, &, Rose GD, (1998) Helix capping. Protein Sci 7, 21-38. (Pubitemid 28133743)
28. Deber CM, Li Z, Joensson C, Glibowicka M, &, Xu GY, (1992) Transmembrane region of wild-type and mutant M13 coat proteins. Conformational role of beta-branched residues. J Biol Chem 267, 5296-5300.
29. Sarafianos SG, Das K, Clark AD Jr, Ding J, Boyer PL, Hughes SH, &, Arnold E, (1999) Lamivudine (3TC) resistance in HIV-1 reverse transcriptase involves steric hindrance with beta-branched amino acids. Proc Natl Acad Sci USA 96, 10027-10032. (Pubitemid 29422506)
30. Mulkidjanian AY, Galperin MY, Makarova KS, Wolf YI, &, Koonin EV, (2008) Evolutionary primacy of sodium bioenergetics. Biol Direct 3, 13.
31. 3-pore in Aquaporin TIP2;2 from wheat. EJB Lett 581, 5413-5417. (Pubitemid 350101516)