3D-QSAR studies of 2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors

Bulletin of the Korean Chemical Society

Volumn 32, Issue 2, 2011, Pages 645-650

  Ghasemi, Jahan B ^a   Pirhadi, Somayeh ^a   Ayati, Mahnaz ^a  

^a K N TOOSI UNIVERSITY OF TECHNOLOGY   (Iran)

Author keywords

All orientation search; Cholesteryl ester transfer protein inhibitors; CoMFA; CoMFA region focusing; CoMSIA

Indexed keywords

ALL ORIENTATION SEARCH; CHOLESTERYL ESTER TRANSFER PROTEINS; COMFA; COMFA REGION FOCUSING; COMSIA;

COMPUTATIONAL CHEMISTRY; DEGREES OF FREEDOM (MECHANICS); ESTERIFICATION; ESTERS; FOCUSING; PROTEINS; THREE DIMENSIONAL;

ENZYME INHIBITION;

EID: 79951892624     PISSN: 02532964     EISSN: 12295949     Source Type: Journal    
DOI: 10.5012/bkcs.2011.32.2.645     Document Type: Article

References (18)

1. Wolfe, M. L.; Rader, D. J. Circulation 2004, 110, 1338.
2. Barter, P. J.; Brewer, H. B. J.; Chapman, M. J.; Hennekens, C. H.; Rader, D. J.; Tall, A. R. Arterioscler. Thromb. Vasc. Biol. 2003, 23, 160.
3. Ruggeri, R. B. Cur. Top. Med. Chem. 2005, 5, 257.
4. Cuchel, M.; Rader, D. J. J. Am. Coll. Cardiol. 2007, 50, 1956.
5. Parini, P.; Rudel, L. L. I. Arterioscler. Thromb. Vasc. Biol. 2003, 23, 374.
6. Huang, Z.; Inazo, A.; Mohara, A.; Higashikata, T.; Mabuchi, H. Clin. Sci. 2002, 103, 587.
7. De Grooth, G. J.; Kuivenhoven, J. A.; Stalenhoef, A. F.; de Graaf, J.; Zwinderman, A. H.; Posma, J. L.; Van Tol, A.; Kastelein, J. J. Circulation 2002, 105, 2159.
8. Boekholdt, S. M.; Kuivenhoven, J. A.; Wareham, N. J.; Peters, R. J. G.; Jukema, J. W.; Luben, R.; Bingham, S. A.; Day, N. E.; Kastelein, J. J. P.; Khaw, K. T. Circulation 2004, 110, 1418.
9. Cramer, R. D., III.; Patterson, D. E.; Bunce, J. D. J. Am. Chem. Soc. 1988, 110, 5959.
10. Klebe, G.; Abraham, U.; Meitzner, T. J. Med. Chem. 1994, 37, 4130.
11. Harikrishnan, L. S.; Kamau, M. G.; Herpin, T. F.; Morton, G. C.; Liu, Y.; Cooper, C. B.; Salvati, M. E.; Qiao, J. X.; Wang, T. C.; Adam, L. P.; Taylor, D. S.; Chen, A. Y. A.; Yin, X.; Seethala, R.; Peterson, T. L.; Nirschl, D. S.; Miller, A. V.; Weigelt, C. A.; Appiah, K. K.; O'Connell, J. C.; Lawrence, R. M. Bioorg. Med. Chem. Lett. 2008, 18, 2640.
12. Wang, R. X.; Gao, Y.; Liu, L.; Lai, L. H. J. Mol. Model. 1998, 4, 276.
13. TM Manual, SYBYL 7.3, Tripos, St. Louis, MO.USA.
14. Baroni, M.; Costantino, G.; Cruciani, G.; Riganelli, D.; Valigi, R.; Clementi, S. Quant. Struct. Act. Relat. 1993, 12, 9.
15. Tropsha, A.; Cho, S. J. J. Med. Chem. 1995, 38, 1060.
16. Clark, R. D.; Fox, P. C. J. Comput- Aided. Mol. Des. 2004, 18, 563.
17. Clark, R. D. J. Comput -Aided. Mol . Des. 2003, 17, 265.
18. Baurin, N.; Vangrevelinghe, E.; Allory, L. M. J. Med. Chem. 2000, 43, 1109.