Individual Differences in Hyperlipidemia and Vitamin E Status in Response to Chronic Alcohol Self-Administration in Cynomolgus Monkeys

Alcoholism: Clinical and Experimental Research

Volumn 35, Issue 3, 2011, Pages 474-483

  Lebold, Katie M ^a   Grant, Kathleen A ^b   Freeman, Willard M ^c   Wiren, Kristine M ^b,d   Miller, Galen W ^a   Kiley, Caitlin ^b   Leonard, Scott W ^a   Traber, Maret G ^a  

^a OREGON STATE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

^d PORTLAND VA MEDICAL CENTER   (United States)

Author keywords

Tocopherol; Apolipoproteins; Chronic Ethanol Consumption; Cynomolgus Monkeys; Lipids; Liver; Oxidative Stress

Indexed keywords

ALCOHOL; ALPHA TOCOPHEROL; APOLIPOPROTEIN C3; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CHOLESTEROL; LIPID; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE PREDISPOSITION; FEMALE; HAPLORHINI; HYPERLIPIDEMIA; INFLAMMATION; LIPID METABOLISM; NONHUMAN; NUTRITIONAL STATUS; PRIORITY JOURNAL; TRIACYLGLYCEROL BLOOD LEVEL;

ALCOHOL DRINKING; ALCOHOLISM; ALPHA-TOCOPHEROL; ANIMALS; ETHANOL; FEMALE; HYPERLIPIDEMIAS; INDIVIDUALITY; MACACA FASCICULARIS; SELF ADMINISTRATION; VITAMIN E;

ANIMALIA; MACACA FASCICULARIS;

EID: 79951887453     PISSN: 01456008     EISSN: 15300277     Source Type: Journal    
DOI: 10.1111/j.1530-0277.2010.01364.x     Document Type: Article

References (47)

1. Achur RN, Freeman WM, Vrana KE (2010) Circulating cytokines as biomarkers of alcohol abuse and alcoholism. J Neuroimmune Pharmacol 5:83-91.
2. Ahuja JK, Goldman JD, Moshfegh AJ (2004) Current status of vitamin E nutriture. Ann N Y Acad Sci 1031:387-390.
3. Barden A, Zilkens RR, Croft K, Mori T, Burke V, Beilin LJ, Puddey IB (2007) A reduction in alcohol consumption is associated with reduced plasma F2-isoprostanes and urinary 20-HETE excretion in men. Free Radic Biol Med 42:1730-1735.
4. Bjorneboe A, Bjorneboe GE (1993) Antioxidant status and alcohol-related diseases. Alcohol Alcohol 28:111-116.
5. Bjorneboe GE, Bjorneboe A, Hagen BF, Morland J, Drevon CA (1987b) Reduced hepatic alpha-tocopherol content after long-term administration of ethanol to rats. Biochim Biophys Acta 918:236-241.
6. Bjorneboe GE, Johnsen J, Bjorneboe A, Bache-Wiig JE, Morland J, Drevon CA (1988a) Diminished serum concentration of vitamin E in alcoholics. Ann Nutr Metab 32:56-61.
7. Bjorneboe GE, Johnsen J, Bjorneboe A, Marklund SL, Skylv N, Hoiseth A, Bache-Wiig JE, Morland J, Drevon CA (1988b) Some aspects of antioxidant status in blood from alcoholics. Alcohol Clin Exp Res 12:806-810.
8. Bjorneboe GA, Johnsen J, Bjorneboe A, Morland J, Drevon CA (1987a) Effect of heavy alcohol consumption on serum concentrations of fat-soluble vitamins and selenium. Alcohol Alcohol Suppl 1:533-537.
9. Cederbaum AI (2001) Introduction-serial review: alcohol, oxidative stress and cell injury. Free Radic Biol Med 31:1524-1526.
10. Chang MK, Binder CJ, Torzewski M, Witztum JL (2002) C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: phosphorylcholine of oxidized phospholipids. Proc Natl Acad Sci U S A 99:13043-13048.
11. Crook MA (2010) Apolipoprotein H: its relevance to cardiovascular disease. Atherosclerosis 209:32-34.
12. Food and Nutrition, Board Institute of Medicine (2000) Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press, Washington, DC.
13. Freeman WM, Salzberg AC, Gonzales SW, Grant KA, Vrana KE (2010) Classification of alcohol abuse by plasma protein biomarkers. Biol Psychiatry 68:219-222.
14. Grant KA, Leng X, Green HL, Szeliga KT, Rogers LS, Gonzales SW (2008) Drinking typography established by scheduled induction predicts chronic heavy drinking in a monkey model of ethanol self-administration. Alcohol Clin Exp Res 32:1824-1838.
15. Grattagliano I, Vendemiale G, Errico F, Bolognino AE, Lillo F, Salerno MT, Altomare E (1997) Chronic ethanol intake induces oxidative alterations in rat testis. J Appl Toxicol 17:307-311.
16. Hartman TJ, Baer DJ, Graham LB, Stone WL, Gunter EW, Parker CE, Albert PS, Dorgan JF, Clevidence BA, Campbell WS, Tomer KB, Judd JT, Taylor PR (2005) Moderate alcohol consumption and levels of antioxidant vitamins and isoprostanes in postmenopausal women. Eur J Clin Nutr 59:161-168.
17. Imhof A, Froehlich M, Brenner H, Boeing H, Pepys MB, Koenig W (2001) Effect of alcohol consumption on systemic markers of inflammation. Lancet 357:763-767.
18. Ivester P, Roberts LJ 2nd, Young T, Stafforini D, Vivian J, Lees C, Young J, Daunais J, Friedman D, Rippe RA, Parsons CJ, Grant KA, Cunningham C (2007) Ethanol self-administration and alterations in the livers of the cynomolgus monkey, Macaca fascicularis. Alcohol Clin Exp Res 31:144-155.
19. Johansen D, Andersen PK, Jensen MK, Schnohr P, Gronbaek M (2003) Nonlinear relation between alcohol intake and high-density lipoprotein cholesterol level: results from the Copenhagen City Heart Study. Alcohol Clin Exp Res 27:1305-1309.
20. Johansson U, Johnsson F, Joelsson B, Berglund M, Akesson B (1986) Selenium status in patients with liver cirrhosis and alcoholism. Br J Nutr 55:227-233.
21. Lecomte E, Herbeth B, Paille F, Steinmetz J, Artur Y, Siest G (1996) Changes in serum apolipoprotein and lipoprotein profile induced by chronic alcohol consumption and withdrawal: determinant effect on heart disease? Clin Chem 42:1666-1675.
22. Lecomte E, Herbeth B, Pirollet P, Chancerelle Y, Arnaud J, Musse N, Paille F, Siest G, Artur Y (1994) Effect of alcohol consumption on blood antioxidant nutrients and oxidative stress indicators. Am J Clin Nutr 60:255-261.
23. Leonard SW, Gumpricht E, Devereaux MW, Sokol RJ, Traber MG (2005) Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration. J Lipid Res 46:1068-1075.
24. Lieber CS (1999) Microsomal ethanol-oxidizing system (MEOS): the first 30years (1968-1998)-a review. Alcohol Clin Exp Res 23:991-1007.
25. Maras JE, Bermudez OI, Qiao N, Bakun PJ, Boody-Alter EL, Tucker KL (2004) Intake of alpha-tocopherol is limited among US adults. J Am Diet Assoc 104:567-575.
26. Marmillot P, Munoz J, Patel S, Garige M, Rosse RB, Lakshman MR (2007) Long-term ethanol consumption impairs reverse cholesterol transport function of high-density lipoproteins by depleting high-density lipoprotein sphingomyelin both in rats and in humans. Metabolism 56:947-953.
27. McDonough KH (2003) Antioxidant nutrients and alcohol. Toxicology 189:89-97.
28. Nelson JS, Fitch CD, Fischer VW, Brown GO Jr, Chou AC (1981) Progressive neuropathologic lesions in vitamin E deficient rhesus monkeys. J Neuropathol Exp Neurol 40:166-185.
29. Odeleye OE, Eskelson CD, Watson RR, Mufti SI, Chvapil M (1991) Vitamin E reduction of lipid peroxidation products in rats fed cod liver oil and ethanol. Alcohol 8:273-277.
30. Onat A, Hergenc G, Sansoy V, Fobker M, Ceyhan K, Toprak S, Assmann G (2003) Apolipoprotein C-III, a strong discriminant of coronary risk in men and a determinant of the metabolic syndrome in both genders. Atherosclerosis 168:81-89.
31. Pepys MB, Hirschfield GM (2003) C-reactive protein: a critical update. J Clin Invest 111:1805-1812.
32. Podda M, Weber C, Traber MG, Packer L (1996) Simultaneous determination of tissue tocopherols, tocotrienols, ubiquinols, and ubiquinones. J Lipid Res 37:893-901.
33. Qian J, Atkinson J, Manor D (2006) Biochemical consequences of heritable mutations in the alpha-tocopherol transfer protein. Biochemistry 45:8236-8242.
34. Schultz M, Leist M, Petrzika M, Gassmann B, Brigelius-Flohé R (1995) Novel urinary metabolite of alpha-tocopherol, 2, 5, 7, 8-tetramethyl-2(2'-carboxyethyl)-6-hydroxychroman, as an indicator of an adequate vitamin E supply? Am J Clin Nutr 62:1527S-1534S.
35. Seitz HK, Kuhn B, von Hodenberg E, Fiehn W, Conradt C, Simanowski UA (1994) Increased messenger RNA levels for low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase in rat liver after long-term ethanol ingestion. Hepatology 20:487-493.
36. Situnayake RD, Crump BJ, Thurnham DI, Davies JA, Gearty J, Davis M (1990) Lipid peroxidation and hepatic antioxidants in alcoholic liver disease. Gut 31:1311-1317.
37. Sozio M, Crabb DW (2008) Alcohol and lipid metabolism. Am J Physiol Endocrinol Metab 295:E10-E16.
38. Takada D, Ezura Y, Ono S, Iino Y, Katayama Y, Xin Y, Wu LL, Larringa-Shum S, Stephenson SH, Hunt SC, Hopkins PN, Emi M (2003) Apolipoprotein H variant modifies plasma triglyceride phenotype in familial hypercholesterolemia: a molecular study in an eight-generation hyperlipidemic family. J Atheroscler Thromb 10:79-84.
39. Teare JP, Greenfield SM, Watson D, Punchard NA, Miller N, Rice-Evans CA, Thompson RP (1994) Lipid peroxidation in rats chronically fed ethanol. Gut 35:1644-1647.
40. Traber MG (2007) Vitamin E regulatory mechanisms. Annu Rev Nutr 27:347-362.
41. Traber MG, Burton GW, Hamilton RL (2004) Vitamin E trafficking. Ann N Y Acad Sci 1031:1-12.
42. Traber MG, Sokol RJ, Ringel SP, Neville HE, Thellman CA, Kayden HJ (1987) Lack of tocopherol in peripheral nerves of vitamin E-deficient patients with peripheral neuropathy. N Engl J Med 317:262-265.
43. Valls-Belles V, Torres Mdel C, Boix L, Muniz P, Gonzalez-Sanjose ML, Codoner-Franch P (2008) alpha-Tocopherol, MDA-HNE and 8-OHdG levels in liver and heart mitochondria of adriamycin-treated rats fed with alcohol-free beer. Toxicology 249:97-101.
44. Vignali DA (2000) Multiplexed particle-based flow cytometric assays. J Immunol Methods 243:243-255.
45. Vivian JA, Green HL, Young JE, Majerksy LS, Thomas BW, Shively CA, Tobin JR, Nader MA, Grant KA (2001) Induction and maintenance of ethanol self-administration in cynomolgus monkeys (Macaca fascicularis): long-term characterization of sex and individual differences. Alcohol Clin Exp Res 25:1087-1097.
46. You M, Fischer M, Deeg MA, Crabb DW (2002) Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP). J Biol Chem 277:29342-29347.
47. Zheng C, Khoo C, Furtado J, Sacks FM (2010) Apolipoprotein C-III and the metabolic basis for hypertriglyceridemia and the dense low-density lipoprotein phenotype. Circulation 121:1722-1734.