A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Repeat-Dose Study of Two Intravenous Acetaminophen Dosing Regimens for the Treatment of Pain After Abdominal Laparoscopic Surgery

Clinical Therapeutics

Volumn 32, Issue 14, 2010, Pages 2348-2369

  Wininger, Steven J ^a   Miller, Howard ^b   Minkowitz, Harold S ^c   Royal, Mike A ^d   Ang, Robert Y ^d   Breitmeyer, James B ^d   Singla, Neil K ^e  

^a Precision Trials   (United States)

^b Woman's Hospital of Texas   (United States)

^c MEMORIAL HERMANN HOSPITAL   (United States)

^d Cadence Pharmaceuticals Inc   (United States)

^e HUNTINGTON MEMORIAL HOSPITAL   (United States)

Author keywords

Abdominal surgery; Analgesia; Intravenous acetaminophen; Laparoscopic surgery; Pain

Indexed keywords

ALANINE AMINOTRANSFERASE; AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; HYDROMORPHONE; MORPHINE; OFIRMEV; OXYCODONE; PARACETAMOL; PLACEBO; UNCLASSIFIED DRUG;

ABDOMINAL SURGERY; ABDOMINAL TENDERNESS; ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BACKACHE; CONSTIPATION; DIARRHEA; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG INFUSION; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; DYSPNEA; FEMALE; FEVER; FLATULENCE; HEADACHE; HUMAN; HYPERTENSION; INJECTION SITE PAIN; INSOMNIA; LABORATORY TEST; LAPAROSCOPIC SURGERY; MAJOR CLINICAL STUDY; MALE; MENTAL DISEASE; MIGRAINE; MULTICENTER STUDY; NAUSEA; PAIN ASSESSMENT; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; RASH; REPEATED DRUG DOSE; SIDE EFFECT; STOMACH EMPTYING; THORAX PAIN; UNITED STATES; UPPER ABDOMINAL PAIN; VISUAL ANALOG SCALE; VOMITING; XEROSTOMIA;

ABDOMEN; ACETAMINOPHEN; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANALGESICS, NON-NARCOTIC; ANALGESICS, OPIOID; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; INJECTIONS, INTRAVENOUS; LAPAROSCOPY; MALE; MIDDLE AGED; PAIN THRESHOLD; PAIN, POSTOPERATIVE; TREATMENT OUTCOME; UNITED STATES; YOUNG ADULT;

EID: 79951821257     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2010.12.011     Document Type: Article

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