Changes in helper lymphocyte chemokine receptor expression and elevation of IP-10 during acute respiratory syncytial virus infection in infants

Pediatric Allergy and Immunology

Volumn 22, Issue 2, 2011, Pages 229-234

  Roe, Michael F E ^a   Bloxham, David M ^a   Cowburn, Andrew S ^a   O'Donnell, Diarmuid R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Apoptosis; Bronchiolitis; Lymphocyte; Respiratory syncytial virus; Virus

Indexed keywords

CHEMOKINE RECEPTOR; CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CXCR3; DNA; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 2 RECEPTOR ALPHA; THYMUS AND ACTIVATION REGULATED CHEMOKINE;

ARTICLE; BLOOD SAMPLING; BRONCHIOLITIS; CELL POPULATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HELPER CELL; HUMAN; INFANT; MALE; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; RESPIRATORY SYNCYTIAL VIRUS INFECTION; TH1 CELL; TH2 CELL;

APOPTOSIS; BRONCHIOLITIS; CHEMOKINE CCL17; CHEMOKINE CXCL10; DNA; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; LYMPHOCYTE COUNT; MALE; RECEPTORS, CCR4; RECEPTORS, CXCR3; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH2 CELLS;

EID: 79951798707     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2010.01032.x     Document Type: Article

References (22)

1. Sigurs N, Gustafsson PM, Bjarnason R, et al. Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am J Respir Crit Care Med 2005: 171: 137-41.
2. Martinez FD. Respiratory syncytial virus bronchiolitis and the pathogenesis of childhood asthma. Pediatr Infect Dis J 2003: 22: S76-82.
3. Rhodes A, Wort SJ, Thomas H, Collinson P, Bennett ED. Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients. Crit Care 2006: 10: R60.
4. Bont L, Heijnen CJ, Kavelaars A, et al. Peripheral blood cytokine responses and disease severity in respiratory syncytial virus bronchiolitis. Eur Respir J 1999: 14: 144-9.
5. Legg JP, Hussain IR, Warner JA, Johnston SL, Warner JO. Type 1 and type 2 cytokine imbalance in acute respiratory syncytial virus bronchiolitis. Am J Respir Crit Care Med 2003: 168: 633-9.
6. Kim CH, Rott L, Kunkel EJ, et al. Rules of chemokine receptor association with T cell polarization in vivo. J Clin Invest 2001: 108: 1331-9.
7. Luster AD. Chemokines--chemotactic cytokines that mediate inflammation. N Engl J Med 1998: 338: 436-45.
8. Bont L, Kimpen JL. Immunological mechanisms of severe respiratory syncytial virus bronchiolitis. Intensive Care Med 2002: 28: 616-21.
9. McNamara PS, Flanagan BF, Hart CA, Smyth RL. Production of chemokines in the lungs of infants with severe respiratory syncytial virus bronchiolitis. J Infect Dis 2005: 191: 1225-32.
10. Culley FJ, Pennycook AM, Tregoning JS, Hussell T, Openshaw PJ. Differential chemokine expression following respiratory virus infection reflects Th1- or Th2-biased immunopathology. J Virol 2006: 80: 4521-7.
11. Wong CK, Lam CW, Wu AK, et al. Plasma inflammatory cytokines and chemokines in severe acute respiratory syndrome. Clin Exp Immunol 2004: 136: 95-103.
12. Ng PC, Lam CW, Li AM, et al. Chemokine response in children with SARS. Arch Dis Child 2005: 90: 422-3.
13. Bussfeld D, Kaufmann A, Meyer RG, Gemsa D, Sprenger H. Differential mononuclear leukocyte attracting chemokine production after stimulation with active and inactivated influenza A virus. Cell Immunol 1998: 186: 1-7.
14. Everard ML, Swarbrick A, Wrightham M, et al. Analysis of cells obtained by bronchial lavage of infants with respiratory syncytial virus infection. Arch Dis Child 1994: 71: 428-32.
15. Jiang Y, Xu J, Zhou C, et al. Characterization of cytokine/chemokine profiles of severe acute respiratory syndrome. Am J Respir Crit Care Med 2005: 171: 850-7.
16. Tasker RC, Roe MF, Bloxham DM, White DK, Ross-Russell RI, O'Donnell DR. The neuroendocrine stress response and severity of acute respiratory syncytial virus bronchiolitis in infancy. Intensive Care Med 2004: 30: 2257-62.
17. Roe MF, Bloxham DM, White DK, Ross-Russell RI, Tasker RT, O'Donnell DR. Lymphocyte apoptosis in acute respiratory syncytial virus bronchiolitis. Clin Exp Immunol 2004: 137: 139-45.
18. Lichtenstein AV, Melkonyan HS, Tomei LD, Umansky SR. Circulating nucleic acids and apoptosis. Ann N Y Acad Sci 2001: 945: 239-49
19. Mcinnes E, Sopp P, Howard CJ, Taylor G. Phenotypic analysis of local cellular responses in calves infected with bovine respiratory syncytial virus. Immunology 1999: 96: 396-403.
20. Akdis M, Trautmann A, Klunker S, et al. T helper (Th) 2 predominance in atopic diseases is due to preferential apoptosis of circulating memory/effector Th1 cells. FASEB J 2003: 17: 1026-35.
21. Warner JO. The early life origins of asthma and related allergic disorders. Arch Dis Child 2004: 89: 97-102.
22. Kurashima K, Fujimura M, Myou S, et al. Effects of oral steroids on blood CXCR3+ and CCR4+ T cells in patients with bronchial asthma. Am J Respir Crit Care Med 2001: 164: 754-8.