Specific immunoadsorption therapy using a tryptophan column in patients with refractory heart failure due to dilated cardiomyopathy

Journal of Clinical Apheresis

Volumn 26, Issue 1, 2011, Pages 1-8

  Nagatomo, Yuji ^a   Baba, Akiyasu ^b   Ito, Hiroyuki ^a   Naito, Kotaro ^c   Yoshizawa, Akihiro ^d   Kurita, Yasuo ^e   Nakamura, Iwao ^f   Monkawa, Toshiaki ^a   Matsubara, Takashi ^e   Wakabayashi, Yasuhisa ^b   Ogawa, Satoshi ^a   Akaishi, Makoto ^b   Yoshikawa, Tsutomu ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KITASATO INSTITUTE HOSPITAL   (Japan)

^c SAITAMA NATIONAL HOSPITAL   (Japan)

^d TOKYO DENTAL COLLEGE   (Japan)

^e Hiratsuka Municipal Hospital   (Japan)

^f Hino Municipal Hospital   (Japan)

Author keywords

adrenergic receptor; autoantibody; cytokine; muscarinic receptor

Indexed keywords

AUTOANTIBODY; BETA 1 ADRENERGIC RECEPTOR; BRAIN NATRIURETIC PEPTIDE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G3; INTERLEUKIN 6; MUSCARINIC M2 RECEPTOR; PROTEIN A; TRYPTOPHAN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; FEMALE; FOLLOW UP; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEMODYNAMICS; HUMAN; IMMUNOADSORPTION; MALE; MORBIDITY; MORTALITY; PATIENT SAFETY; SURVIVAL;

ADULT; AGED; AMINO ACID SEQUENCE; CARDIOMYOPATHY, DILATED; FEMALE; HEART FAILURE; HUMANS; IMMUNOGLOBULIN G; IMMUNOSORBENT TECHNIQUES; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NATRIURETIC PEPTIDE, BRAIN; TRYPTOPHAN; VENTRICULAR FUNCTION, LEFT;

EID: 79951737351     PISSN: 07332459     EISSN: 10981101     Source Type: Journal    
DOI: 10.1002/jca.20268     Document Type: Article

References (39)

1. Caforio AL, Grazzini M, Mann JM, Keeling PJ, Bottazzo GF, McKenna WJ, Schiaffino S,. Identification of alpha- and beta-cardiac myosin heavy chain isoforms as major autoantigens in dilated cardiomyopathy. Circulation 1992; 85: 1734-1742.
2. Schultheiss HP, Schulze K, Schauer R, Witzenbichler B, Strauer BE,. Antibody-mediated imbalance of myocardial energy metabolism. A causal factor of cardiac failure? Circ Res 1995; 76: 64-72.
3. Limas CJ, Goldenberg IF, Limas C,. Autoantibodies against beta-adrenoceptors in human idiopathic dilated cardiomyopathy. Circ Res 1989; 64: 97-103. (Pubitemid 19028507)
4. Magnusson Y, Wallukat G, Waagstein F, Hjalmarson A, Hoebeke J,. Autoimmunity in idiopathic dilated cardiomyopathy. Characterization of antibodies against the beta 1-adrenoceptor with positive chronotropic effect. Circulation 1994; 89: 2760-2767. (Pubitemid 24173697)
5. Iwata M, Yoshikawa T, Baba A, Anzai T, Nakamura I, Wainai Y, Takahashi T, Ogawa S,. Autoimmunity against the second extracellular loop of beta(1)-adrenergic receptors induces beta-adrenergic receptor desensitization and myocardial hypertrophy in vivo. Circ Res 2001; 88: 578-586. (Pubitemid 32275793)
6. Christ T, Wettwer E, Dobrev D, Adolph E, Knaut M, Wallukat G, Ravens U,. Autoantibodies against the beta1 adrenoceptor from patients with dilated cardiomyopathy prolong action potential duration and enhance contractility in isolated cardiomyocytes. J Mol Cell Cardiol 2001; 33: 1515-1525. (Pubitemid 32681669)
7. Jahns R, Boivin V, Hein L, Triebel S, Angermann CE, Ertl G, Lohse MJ,. Direct evidence for a beta 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy. J Clin Invest 2004; 113: 1419-1429. (Pubitemid 39071697)
8. Jane-wit D, Altuntas CZ, Johnson JM, Yong S, Wickley PJ, Clark P, Wang Q, Popovic ZB, Penn MS, Damron DS, Perez DM, Tuohy VK,. Beta 1-adrenergic receptor autoantibodies mediate dilated cardiomyopathy by agonistically inducing cardiomyocyte apoptosis. Circulation 2007; 116: 399-410. (Pubitemid 47196545)
9. Dorffel WV, Felix SB, Wallukat G, Brehme S, Bestvater K, Hofmann T, Kleber FX, Baumann G, Reinke P,. Short-term hemodynamic effects of immunoadsorption in dilated cardiomyopathy. Circulation 1997; 95: 1994-1997. (Pubitemid 27184263)
10. Felix SB, Staudt A, Dorffel WV, Stangl V, Merkel K, Pohl M, Docke WD, Morgera S, Neumayer HH, Wernecke KD, Wallukat G, Stangl K, Baumann G,. Hemodynamic effects of immunoadsorption and subsequent immunoglobulin substitution in dilated cardiomyopathy: three-month results from a randomized study. J Am Coll Cardiol 2000; 35: 1590-1598. (Pubitemid 30307505)
11. Muller J, Wallukat G, Dandel M, Bieda H, Brandes K, Spiegelsberger S, Nissen E, Kunze R, Hetzer R,. Immunoglobulin adsorption in patients with idiopathic dilated cardiomyopathy. Circulation 2000; 101: 385-391. (Pubitemid 30067394)
12. Knebel F, Bohm M, Staudt A, Borges AC, Tepper M, Jochmann N, Wernicke KD, Felix S, Baumann G,. Reduction of morbidity by immunoadsorption therapy in patients with dilated cardiomyopathy. Int J Cardiol 2004; 97: 517-520. (Pubitemid 39550704)
13. Dorffel WV, Wallukat G, Dorffel Y, Felix SB, Baumann G,. Immunoadsorption in idiopathic dilated cardiomyopathy, a 3-year follow-up. Int J Cardiol 2004; 97: 529-534. (Pubitemid 39550706)
14. Staudt A, Hummel A, Ruppert J, Dorr M, Trimpert C, Birkenmeier K, Krieg T, Staudt Y, Felix SB,. Immunoadsorption in dilated cardiomyopathy: 6-month results from a randomized study. Am Heart J 2006; 152: 712,e711- e716.
15. Bruggemann M, Williams GT, Bindon CI, Clark MR, Walker MR, Jefferis R, Waldmann H, Neuberger MS,. Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies. J Exp Med 1987; 166: 1351-1361. (Pubitemid 18051427)
16. Mulder AH, Stegeman CA, Kallenberg CG,. Activation of granulocytes by anti-neutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis: a predominant role for the IgG3 subclass of ANCA. Clin Exp Immunol 1995; 101: 227-232.
17. Warraich RS, Noutsias M, Kazak I, Seeberg B, Dunn MJ, Schultheiss HP, Yacoub MH, Kuhl U,. Immunoglobulin G3 cardiac myosin autoantibodies correlate with left ventricular dysfunction in patients with dilated cardiomyopathy: immunoglobulin G3 and clinical correlates. Am Heart J 2002; 143: 1076-1084. (Pubitemid 34666901)
18. Shibuya N, Sato T, Osame M, Takegami T, Doi S, Kawanami S,. Immunoadsorption therapy for myasthenia gravis. J Neurol Neurosurg Psychiatry 1994; 57: 578-581. (Pubitemid 24151250)
19. Hirata N, Kuriyama T, Yamawaki N,. Immusorba TR and PH. Ther Apher Dial 2003; 7: 85-90. (Pubitemid 36648049)
20. Iwata M, Yoshikawa T, Baba A, Anzai T, Mitamura H, Ogawa S,. Autoantibodies against the second extracellular loop of beta1-adrenergic receptors predict ventricular tachycardia and sudden death in patients with idiopathic dilated cardiomyopathy. J Am Coll Cardiol 2001; 37: 418-424.
21. Baba A, Yoshikawa T, Fukuda Y, Sugiyama T, Shimada M, Akaishi M, Tsuchimoto K, Ogawa S, Fu M,. Autoantibodies against M2-muscarinic acetylcholine receptors: new upstream targets in atrial fibrillation in patients with dilated cardiomyopathy. Eur Heart J 2004; 25: 1108-1115. (Pubitemid 38834068)
22. Christ T, Dobrev D, Wallukat G, Schuler S, Ravens U,. Acute hemodynamic effects during immunoadsorption in patients with dilated cardiomyopathy positive for beta 1-adrenoceptor autoantibodies. Methods Find Exp Clin Pharmacol 2001; 23: 141-144. (Pubitemid 32720611)
23. Cooper LT, Belohlavek M, Korinek J, Yoshifuku S, Sengupta PP, Burgstaler EA, Winters JL,. A pilot study to assess the use of protein a immunoadsorption for chronic dilated cardiomyopathy. J Clin Apher 2007; 22: 210-214. (Pubitemid 47320235)
24. McNamara DM, Rosenblum WD, Janosko KM, Trost MK, Villaneuva FS, Demetris AJ, Murali S, Feldman AM,. Intravenous immune globulin in the therapy of myocarditis and acute cardiomyopathy. Circulation 1997; 95: 2476-2478. (Pubitemid 27233111)
25. Staudt A, Dorr M, Staudt Y, Bohm M, Probst M, Empen K, Plotz S, Maschke HE, Hummel A, Baumann G, Felix SB,. Role of immunoglobulin G3 subclass in dilated cardiomyopathy: results from protein A immunoadsorption. Am Heart J 2005; 150: 729-736. (Pubitemid 41396508)
26. Braun N, Gutenberger S, Erley CM, Risler T,. Immunoglobulin and circulating immune complex kinetics during immunoadsorption onto protein A sepharose. Transfus Sci 1998; 19 Suppl: 25-31.
27. Staudt A, Bohm M, Knebel F, Grosse Y, Bischoff C, Hummel A, Dahm JB, Borges A, Jochmann N, Wernecke KD, Wallukat G, Baumann G, Felix SB,. Potential role of autoantibodies belonging to the immunoglobulin G-3 subclass in cardiac dysfunction among patients with dilated cardiomyopathy. Circulation 2002; 106: 2448-2453. (Pubitemid 35278800)
28. Magnusson Y, Marullo S, Hoyer S, Waagstein F, Andersson B, Vahlne A, Guillet JG, Strosberg AD, Hjalmarson A, Hoebeke J,. Mapping of a functional autoimmune epitope on the beta 1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy. J Clin Invest 1990; 86: 1658-1663. (Pubitemid 20372617)
29. Magnusson Y, Hjalmarson A, Hoebeke J,. Beta 1-adrenoceptor autoimmunity in cardiomyopathy. Int J Cardiol 1996; 54: 137-141.
30. Jahns R, Boivin V, Siegmund C, Inselmann G, Lohse MJ, Boege F,. Autoantibodies activating human beta1-adrenergic receptors are associated with reduced cardiac function in chronic heart failure. Circulation 1999; 99: 649-654. (Pubitemid 29077363)
31. Nagatomo Y, Yoshikawa T, Kohno T, Yoshizawa A, Baba A, Anzai T, Meguro T, Satoh T, Ogawa S,. A pilot study on the role of autoantibody targeting the beta1-adrenergic receptor in the response to beta-blocker therapy for congestive heart failure. J Card Fail 2009; 15: 224-232.
32. Stork S, Boivin V, Horf R, Hein L, Lohse MJ, Angermann CE, Jahns R,. Stimulating autoantibodies directed against the cardiac beta1-adrenergic receptor predict increased mortality in idiopathic cardiomyopathy. Am Heart J 2006; 152: 697-704. (Pubitemid 44396891)
33. Wallukat G, Muller J, Hetzer R,. Specific removal of beta1-adrenergic autoantibodies from patients with idiopathic dilated cardiomyopathy. N Engl J Med 2002; 347: 1806. (Pubitemid 35375628)
34. Mobini R, Staudt A, Felix SB, Baumann G, Wallukat G, Deinum J, Svensson H, Hjalmarson A, Fu M,. Hemodynamic improvement and removal of autoantibodies against beta1-adrenergic receptor by immunoadsorption therapy in dilated cardiomyopathy. J Autoimmun 2003; 20: 345-350. (Pubitemid 36677526)
35. Felix SB, Staudt A, Landsberger M, Grosse Y, Stangl V, Spielhagen T, Wallukat G, Wernecke KD, Baumann G, Stangl K,. Removal of cardiodepressant antibodies in dilated cardiomyopathy by immunoadsorption. J Am Coll Cardiol 2002; 39: 646-652. (Pubitemid 34158161)
36. Staudt A, Staudt Y, Dorr M, Bohm M, Knebel F, Hummel A, Wunderle L, Tiburcy M, Wernecke KD, Baumann G, Felix SB,. Potential role of humoral immunity in cardiac dysfunction of patients suffering from dilated cardiomyopathy. J Am Coll Cardiol 2004; 44: 829-836. (Pubitemid 39099581)
37. Baba A,. Autoantigen estimation and simple screening assay against cardiodepressant autoantibodies in patients with dilated cardiomyopathy. Ther Apher Dial 2008; 12: 109-116. (Pubitemid 351490243)
38. Oda S, Hirasawa H, Shiga H, Nakanishi K, Matsuda K, Nakamura M, Ikeda H, Sakai M,. Cytokine adsorptive property of various adsorbents in immunoadsorption columns and a newly developed adsorbent: an in vitro study. Blood Purif 2004; 22: 530-536. (Pubitemid 40069623)
39. Daniels LB, Maisel AS,. Natriuretic peptides. J Am Coll Cardiol 2007; 50: 2357-2368. (Pubitemid 50011582)