β1-Adrenergic receptor autoantibodies mediate dilated cardiomyopathy by agonistically inducing cardiomyocyte apoptosis

Circulation

Volumn 116, Issue 4, 2007, Pages 399-410

  Jane Wit, Daniel ^a   Altuntas, Cengiz Z ^a   Johnson, Justin M ^a   Yong, Sandro ^a   Wickley, Peter J ^a   Clark, Pamela ^a   Wang, Qing ^a   Popović, Zoran B ^a   Penn, Marc S ^a   Damron, Derek S ^a   Perez, Dianne M ^a   Tuohy, Vincent K ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Antibodies; Apoptosis; Autoimmunity; Cardiomyopathy; Heart failure; Receptors, adrenergic, beta

Indexed keywords

ANTIGEN; AUTOANTIBODY; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR ANTIBODY; BETA 2 ADRENERGIC RECEPTOR; CALCIUM; CASPASE 3; CASPASE INHIBITOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; RECEPTOR ANTIBODY; UNCLASSIFIED DRUG;

ADRENERGIC RECEPTOR BLOCKING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; ENZYME ACTIVATION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; IMMUNOADSORPTION; IN VIVO STUDY; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PATHOGENESIS; PHARMACOLOGICAL BLOCKING; PREVENTIVE MEDICINE; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING;

ADRENERGIC BETA-AGONISTS; ANIMALS; APOPTOSIS; AUTOANTIBODIES; AUTOIMMUNE DISEASES; CARDIOMYOPATHY, DILATED; CELLS, CULTURED; HUMANS; MALE; MICE; MYOCYTES, CARDIAC; RECEPTORS, ADRENERGIC, BETA-1;

EID: 34547599139     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.106.683193     Document Type: Article

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