MnTMPyP, a superoxide dismutase/catalase mimetic, decreases inflammatory indices in ischemic acute kidney injury

Inflammation Research

Volumn 60, Issue 3, 2011, Pages 299-307

  Mortensen, Jordan ^a   Shames, Brian ^a,b   Johnson, Christopher P ^a,b   Nilakantan, Vani ^a,b  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

^b AURORA HEALTH CARE   (United States)

Author keywords

Inflammatory cytokines; Ischemia reperfusion; Kidney; MnTMPyP; Reactive oxygen; TNF

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTIINFLAMMATORY AGENT; CATALASE; CREATININE; INTERLEUKIN 13; INTERLEUKIN 2; INTERLEUKIN 4; SUPEROXIDE DISMUTASE; TETRAKIS(1 METHYL 4 PYRIDYL)PORPHYRIN MANGANESE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFICACY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY ARTERY; KIDNEY ISCHEMIA; KIDNEY PROXIMAL TUBULE; MACROPHAGE; MALE; NONHUMAN; RAT; REPERFUSION INJURY; SWINE;

ACUTE KIDNEY INJURY; ADENOSINE TRIPHOSPHATE; ANIMALS; CATALASE; CELLS, CULTURED; CYTOKINES; INFLAMMATION; KIDNEY; KIDNEY TUBULES; MALE; METALLOPORPHYRINS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; REPERFUSION INJURY; SUPEROXIDE DISMUTASE; SWINE;

EID: 79951727139     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-010-0268-3     Document Type: Article

References (35)

1. PK Chatterjee Z Todorovic A Sivarajah H Mota-Filipe PA Brown KN Stewart, et al. 2004 Differential effects of caspase inhibitors on the renal dysfunction and injury caused by ischemia-reperfusion of the rat kidney Eur J Pharmacol 503 173 183 1:CAS:528:DC%2BD2cXovFansro%3D 10.1016/j.ejphar.2004.09.025 15496312 (Pubitemid 39445956)
2. PC Dagher 2004 Apoptosis in ischemic renal injury: roles of GTP depletion and p53 Kidney Int 66 506 509 1:CAS:528:DC%2BD2cXmvVegs7o%3D 10.1111/j.1523-1755.2004.761-7.x 15253698 (Pubitemid 38981987)
3. A Djamali A Vidyasagar M Adulla D Hullett S Reese 2009 Nox-2 is a modulator of fibrogenesis in kidney allografts Am J Transplant 9 74 82 1:CAS:528:DC%2BD1MXitlWnurs%3D 10.1111/j.1600-6143.2008.02463.x 18976289
4. N Lameire 2005 The pathophysiology of acute renal failure Crit Care Clin 21 197 210 10.1016/j.ccc.2005.01.001 15781157 (Pubitemid 40386749)
5. W Lieberthal JS Koh JS Levine 1998 Necrosis and apoptosis in acute renal failure Semin Nephrol 18 505 518 1:CAS:528:DyaK1cXmt1Gkuro%3D 9754603 (Pubitemid 28430754)
6. W Lieberthal JS Levine 1996 Mechanisms of apoptosis and its potential role in renal tubular epithelial cell injury Am J Physiol 271 F477 F488 1:CAS:528:DyaK28XmtFejt7g%3D 8853409
7. MC Avunduk T Yurdakul E Erdemli A Yavuz 2003 Prevention of renal damage by alpha tocopherol in ischemia and reperfusion models of rats Urol Res 31 280 285 1:CAS:528:DC%2BD3sXmsFykt7g%3D 10.1007/s00240-003-0329-y 12844243 (Pubitemid 37122174)
8. R Baliga N Ueda PD Walker SV Shah 1999 Oxidant mechanisms in toxic acute renal failure Drug Metab Rev 31 971 997 1:CAS:528:DyaK1MXnvFCitrc%3D 10.1081/DMR-100101947 10575556
9. ML Barnard SJ Snyder TD Engerson JF Turrens 1993 Antioxidant enzyme status of ischemic and postischemic liver and ischemic kidney in rats Free Radic Biol Med 15 227 232 1:CAS:528:DyaK2cXitFCht7k%3D 10.1016/0891-5849(93)90064-2 8375697 (Pubitemid 23218827)
10. PK Chatterjee S Cuzzocrea PA Brown K Zacharowski KN Stewart H Mota-Filipe, et al. 2000 Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat Kidney Int 58 658 673 1:CAS:528:DC%2BD3cXlvFagsrg%3D 10.1046/j.1523-1755.2000.00212.x 10916089 (Pubitemid 30620015)
11. PK Chatterjee NS Patel EO Kvale PA Brown KN Stewart H Mota-Filipe, et al. 2004 EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney Am J Nephrol 24 165 177 1:CAS:528: DC%2BD2cXivVSjs7k%3D 10.1159/000076547 14752229 (Pubitemid 38456627)
12. V Nilakantan H Liang CJ Maenpaa CP Johnson 2008 Differential patterns of peroxynitrite mediated apoptosis in proximal tubular epithelial cells following ATP depletion recovery Apoptosis 13 621 633 1:CAS:528:DC%2BD1cXkslGqtL4%3D 10.1007/s10495-008-0196-7 18357533
13. JM Thurman D Ljubanovic CL Edelstein GS Gilkeson VM Holers 2003 Lack of a functional alternative complement pathway ameliorates ischemic acute renal failure in mice J Immunol 170 1517 1523 1:CAS:528:DC%2BD3sXnvVOruw%3D%3D 12538716 (Pubitemid 36139523)
14. KK Donnahoo DR Meldrum R Shenkar CS Chung E Abraham AH Harken 2000 Early renal ischemia, with or without reperfusion, activates NFkappaB and increases TNF-alpha bioactivity in the kidney J Urol 163 1328 1332 1:CAS:528: DC%2BD3cXisVSrurs%3D 10.1016/S0022-5347(05)67772-5 10737538 (Pubitemid 30169434)
15. KK Donnahoo X Meng A Ayala MP Cain AH Harken DR Meldrum 1999 Early kidney TNF-alpha expression mediates neutrophil infiltration and injury after renal ischemia-reperfusion Am J Physiol 277 R922 R929 1:CAS:528:DyaK1MXmt1Gis7c%3D 10484513
16. KK Donnahoo BD Shames AH Harken DR Meldrum 1999 Review article: the role of tumor necrosis factor in renal ischemia-reperfusion injury J Urol 162 196 203 1:CAS:528:DyaK1MXktFenu7w%3D 10.1097/00005392-199907000-00068 10379787 (Pubitemid 29420927)
17. DE Choi JY Jeong BJ Lim KR Na YT Shin KW Lee 2009 Pretreatment with the tumor nerosis factor-alpha blocker etanercept attenuated ischemia-reperfusion renal injury Transplant Proc 41 3590 3596 1:CAS:528:DC%2BD1MXhsVajsb3P 10.1016/j.transproceed.2009.05.042 19917350
18. SK Jo SA Sung WY Cho KJ Go HK Kim 2006 Macrophages contribute to the initiation of ischaemic acute renal failure in rats Nephrol Dial Transplant 21 1231 1239 1:CAS:528:DC%2BD28XjslKru78%3D 10.1093/ndt/gfk047 16410269
19. SA Sung SK Jo WY Cho NH Won HK Kim 2007 Reduction of renal fibrosis as a result of liposome encapsulated clodronate induced macrophage depletion after unilateral ureteral obstruction in rats Nephron Exp Nephrol 105 e1 e9 10.1159/000096859 17106213 (Pubitemid 46006571)
20. HL Liang G Hilton J Mortensen K Regner CP Johnson V Nilakantan 2009 MnTMPyP, a cell-permeant SOD mimetic, reduces oxidative stress and apoptosis following renal ischemia-reperfusion Am J Physiol Renal Physiol 296 F266 F276 1:CAS:528:DC%2BD1MXitVejtbs%3D 10.1152/ajprenal.90533.2008 19091787
21. CJ Maenpaa BD Shames SK Van Why CP Johnson V Nilakantan 2008 Oxidant-mediated apoptosis in proximal tubular epithelial cells following ATP depletion and recovery Free Radic Biol Med 44 518 526 1:CAS:528: DC%2BD1cXhsFykur4%3D 10.1016/j.freeradbiomed.2007.10.040 17997382
22. T Wang B Liu L Qin B Wilson JS Hong 2004 Protective effect of the SOD/catalase mimetic MnTMPyP on inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuronal-glial cultures J Neuroimmunol 147 68 72 1:CAS:528:DC%2BD2cXltVOntQ%3D%3D 10.1016/j.jneuroim.2003.10.040 14741430 (Pubitemid 38114949)
23. V Nilakantan X Zhou G Hilton Y Shi JE Baker AK Khanna, et al. 2006 Antagonizing reactive oxygen by treatment with a manganese (III) metalloporphyrin-based superoxide dismutase mimetic in cardiac transplants J Thorac Cardiovasc Surg 131 898 906 1:CAS:528:DC%2BD28XksVyhsrg%3D 10.1016/j.jtcvs.2005.11.015 16580450
24. HL Liang J Arsenault J Mortensen F Park CP Johnson V Nilakantan 2009 Partial attenuation of cytotoxicity and apoptosis by SOD1 in ischemic renal epithelial cells Apoptosis 14 1176 1189 1:CAS:528:DC%2BD1MXhtV2htrbF 10.1007/s10495-009-0393-z 19685188
25. SK Jo DR Cha WY Cho HK Kim KH Chang SY Yun, et al. 2002 Inflammatory cytokines and lipopolysaccharide induce Fas-mediated apoptosis in renal tubular cells Nephron 91 406 415 1:CAS:528:DC%2BD38XlsFOguro%3D 10.1159/000064280 12119470 (Pubitemid 34765238)
26. D Kaminska B Tyran O Mazanowska J Rabczynski P Szyber D Patrzalek, et al. 2007 Cytokine gene expression in kidney allograft biopsies after donor brain death and ischemia-reperfusion injury using in situ reverse-transcription polymerase chain reaction analysis Transplantation 84 1118 1124 1:CAS:528:DC%2BD2sXht1ykurfF 10.1097/01.tp.0000287190.86654.74 17998866 (Pubitemid 350125353)
27. MP Nair MR Nampoory KV Johny JN Costandi M Abdulhalim W El-Reshaid, et al. 2001 Induction immunosuppression with interleukin-2 receptor antibodies (basiliximab and daclizumab) in renal transplant recipients Transplant Proc 33 2767 2769 1:CAS:528:DC%2BD3MXlslGmt7Y%3D 10.1016/S0041-1345(01)02184-4 11498153 (Pubitemid 32725883)
28. H Wu B Zhu Y Shimoishi Y Murata Y Nakamura 2009 (-)-Epigallocatechin-3- gallate induces up-regulation of Th1 and Th2 cytokine genes in Jurkat T cells Arch Biochem Biophys 483 99 105 1:CAS:528:DC%2BD1MXitFSmtrY%3D 10.1016/j.abb.2008.12.010 19135025
29. XD Shen B Ke Y Zhai F Gao S Tsuchihashi CR Lassman, et al. 2007 Absence of toll-like receptor 4 (TLR4) signaling in the donor organ reduces ischemia and reperfusion injury in a murine liver transplantation model Liver Transpl 13 1435 1443 10.1002/lt.21251 17902130 (Pubitemid 47629578)
30. E Vannier LC Miller CA Dinarello 1992 Coordinated antiinflammatory effects of interleukin 4: interleukin 4 suppresses interleukin 1 production but up-regulates gene expression and synthesis of interleukin 1 receptor antagonist Proc Natl Acad Sci USA 89 4076 4080 1:CAS:528:DyaK38XisFersrs%3D 10.1073/pnas.89.9.4076 1533284
31. P Sharma R Chakraborty L Wang B Min ML Tremblay T Kawahara, et al. 2008 Redox regulation of interleukin-4 signaling Immunity 29 551 564 1:CAS:528:DC%2BD1cXhtlWntb7I 10.1016/j.immuni.2008.07.019 18957266
32. T Koken M Serteser A Kahraman G Akbulut ON Dilek 2004 Which is more effective in the prevention of renal ischemia-reperfusion-induced oxidative injury in the early period in mice: interleukin (IL)-10 or anti-IL-12? Clin Biochem 37 50 55 10.1016/j.clinbiochem.2003.10.001 14675562 (Pubitemid 37522125)
33. J Deng Y Kohda H Chiao Y Wang X Hu SM Hewitt, et al. 2001 Interleukin-10 inhibits ischemic and cisplatin-induced acute renal injury Kidney Int 60 2118 2128 1:CAS:528:DC%2BD3MXpt1Kjsrc%3D 10.1046/j.1523-1755.2001.00043.x 11737586 (Pubitemid 33070455)
34. D Nandi MK Mishra A Basu B Bishayi 2009 Protective effects of interleukin-6 in lipopolysaccharide (LPS)-induced experimental endotoxemia are linked to alteration in hepatic anti-oxidant enzymes and endogenous cytokines Immunobiology 215 443 451 10.1016/j.imbio.2009.08.003 19773091
35. SJ Yu DJ Oh SH Yu 2008 The investigation of macrophage infiltration in the early phase of ischemic acute renal failure in mice Korean J Intern Med 23 64 71 1:CAS:528:DC%2BD1cXotFaksrg%3D 10.3904/kjim.2008.23.2.64 18646508 (Pubitemid 351890857)