Change in glucose metabolism measured by 18F-FDG PET/CT as a predictor of histopathologic response to neoadjuvant treatment in rectal cancer

Abdominal Imaging

Volumn 36, Issue 1, 2011, Pages 38-45

  Guerra, Luca ^a   Niespolo, Rita ^a   Di Pisa, Giuseppe ^a   Ippolito, Davide ^a   De Ponti, Elena ^a   Terrevazzi, Sara ^a   Bovo, Giorgio ^a   Sironi, Sandro ^a   Gardani, Gianstefano ^a   Messa, Cristina ^a,b  

^a SAN GERARDO HOSPITAL   (Italy)

^b INSTITUTE OF MOLECULAR BIOIMAGING AND PHYSIOLOGY   (Italy)

Author keywords

Glucose metabolism; Neoadjuvant therapy; PET CT; Rectal cancer; SUV; Therapy response

Indexed keywords

FLUORODEOXYGLUCOSE F 18;

ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CLINICAL ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; FEMALE; GLUCOSE METABOLISM; HISTOPATHOLOGY; HUMAN; MALE; OUTCOME ASSESSMENT; POSITRON EMISSION TOMOGRAPHY; PREDICTION; PRIORITY JOURNAL; RECTUM CANCER; SENSITIVITY AND SPECIFICITY; TUMOR REGRESSION;

ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; BLOOD GLUCOSE; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; OBSERVER VARIATION; POSITRON-EMISSION TOMOGRAPHY; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RADIOPHARMACEUTICALS; RECTAL NEOPLASMS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 79951676749     PISSN: 09428925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00261-009-9594-8     Document Type: Article

References (30)

1. E Kapiteijn CAM Marijnen ID Nagtegaal, et al. 2001 Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer N Engl J Med 345 638 646 1:STN:280:DC%2BD3Mvps1ektw%3D%3D 10.1056/NEJMoa010580 11547717
2. R Sauer H Becker W Hohenberger, et al. 2004 Preoperative versus postoperative chemoradiotherapy for rectal cancer N Engl J Med 351 1731 1740 1:CAS:528:DC%2BD2cXovFSksbo%3D 10.1056/NEJMoa040694 15496622 (Pubitemid 39383208)
3. JF Bosset L Collette G Calais, et al. 2006 Chemotherapy with preoperative radiotherapy in rectal cancer N Engl J Med 355 1114 1123 1:CAS:528: DC%2BD28XpsFKkur8%3D 10.1056/NEJMoa060829 16971718 (Pubitemid 44394918)
4. BD Minsky AM Cohen N Kemeny, et al. 1992 Enhancement of radiation-induced downstaging of rectal cancer by fluorouracil and high-dose leucovorin chemotherapy J Clin Oncol 10 79 84 1:STN:280:DyaK38%2Fpt1SksQ%3D%3D 1727928
5. C Rodel GG Grabenbauer C Schick T Papadopoulos W Hohenberger R Sauer 2000 Preoperative radiation with concurrent 5-fluorouracil for locally advanced T4-primary rectal cancer Strahlenther Onkol 176 161 167 1:STN:280: DC%2BD3c3nt1alug%3D%3D 10.1007/s000660050051 10812388 (Pubitemid 30212059)
6. JG Guillem DB Chessin AM Cohen, et al. 2005 Long-term oncologic outcome following preoperative combined modality therapy and total mesorectal excision of locally advanced rectal cancer Ann Surg 241 829 836 10.1097/01.sla. 0000161980.46459.96 15849519 (discussion 36-38) (Pubitemid 40604929)
7. A Jemal RC Tiwari T Murray, et al. 2004 Cancer statistics, 2004 CA Cancer J Clin 54 8 29 10.3322/canjclin.54.1.8 14974761 (Pubitemid 38443417)
8. H Amthauer T Denecke B Rau, et al. 2004 Response prediction by FDG-PET after neoadjuvant radiochemotherapy and combined regional hyperthermia of rectal cancer: correlation with endorectal ultrasound and histopathology Eur J Med Mol Imaging 31 811 819 10.1007/s00259-003-1453-1 (Pubitemid 38758350)
9. KT Hoffmann B Rau P Wust 2002 Restaging of locally advanced carcinoma of the rectum with MR imaging after preoperative radio-chemotherapy plus regional hyperthermia Strahlenther Onkol 178 386 392 10.1007/s00066-002-0938-3 12163993 (Pubitemid 34665786)
10. T Deneke B Rau KT Hoffmann 2005 Comparison of CT, MRI and FDG-PET in response prediction of patients with locally advanced rectal cancer after multimodal preoperative therapy: is there a benefit in using functional imaging? Eur Radiol 15 1658 1666 10.1007/s00330-005-2658-4 (Pubitemid 41102362)
11. CC Chen RC Lee JK Lin LW Wang SH Yang 2005 How accurate is magnetic resonance imaging in restaging rectal cancer in patients receiving preoperative combined chemoradiotherapy? Dis Colon Rectum 48 722 728 10.1007/s10350-004-0851- 1 15747073 (Pubitemid 40880719)
12. B Rau M Hunerbein C Barth, et al. 1999 Accuracy of endorectal ultrasound after preoperative radiochemotherapy in locally advanced rectal cancer Surg Endosc 13 980 984 1:STN:280:DyaK1MvlslGitQ%3D%3D 10.1007/s004649901151 10526031 (Pubitemid 29471358)
13. WA Weber K Ott HJ Dittler, et al. 2001 Prediction of response to preoperative chemotherapy in adenocarcinomas of the esophagogastric junction by metabolic imaging J Clin Oncol 19 3058 3065 1:STN:280:DC%2BD3MzksFGhsQ%3D%3D 11408502 (Pubitemid 32565444)
14. K Ott U Fink K Becker, et al. 2003 Prediction of response to preoperative chemotherapy in gastric carcinoma by metabolic imaging: results of a prospective trial J Clin Oncol 21 4604 4610 1:CAS:528:DC%2BD2cXpsVWqurg%3D 10.1200/JCO.2003.06.574 14673049 (Pubitemid 46594034)
15. K Ott W Weber F Lordick, et al. 2006 Metabolic imaging predicts response, survival, and recurrence in adenocarcinoma of the esophagogastric junction J Clin Oncol 24 4692 4698 10.1200/JCO.2006.06.7801 16966684 (Pubitemid 46646244)
16. BL Brucher W Weber M Bauer, et al. 2001 Neoadjuvant therapy of esophageal squamous cell carcinoma: response evaluation by positron emission tomography Ann Surg 233 300 309 1:STN:280:DC%2BD3M7ps1emug%3D%3D 10.1097/00000658- 200103000-00002 11224616 (Pubitemid 32187807)
17. V Kalff C Duong EG Drummond, et al. 2006 Findings on 18FFDG PET scans after neoadjuvant chemoradiation provides prognostic stratification in patients with locally advanced rectal carcinoma subsequently treated by radical surgery J Nucl Med 47 14 22 16391182 (Pubitemid 46768507)
18. GL Cascini A Avallone P Delrio, et al. 2006 18F-FDG PET is an early predictor of pathologic tumor response to preoperative radiochemotherapy in locally advanced rectal cancer J Nucl Med 47 1241 1248 1:CAS:528: DC%2BD28XptVWqu74%3D 16883000 (Pubitemid 47544874)
19. C Capirci D Rubello F Chierichetti, et al. 2006 Long-term prognostic value of 18F-FDG PET in patients with locally advanced rectal cancer previously treated with neoadjuvant radiochemotherapy AJR 187 202 208 10.2214/AJR.05.0902
20. C Capirci L Rampin AP Erba, et al. 2007 Sequential FDG-PET/CT reliably predicts response of locally advanced rectal cancer to neo-adjuvant chemo-radiation therapy Eur J Nucl Med Mol Imaging 34 1583 1593 1:CAS:528:DC%2BD2sXhtVOit7bE 10.1007/s00259-007-0426-1 17503039 (Pubitemid 47476915)
21. FA Calvo M Domper R Matute, et al. 2004 18F-FDG positron emission tomography staging and restaging in rectal cancer treated with preoperative chemoradiation Int J Radiat Oncol Biol Phys 58 528 535 10.1016/j.ijrobp.2003.09. 058 14751524 (Pubitemid 38142480)
22. R Rosenberg K Herrmann R Gertler, et al. 2009 The predictive value of metabolic response to preoperative radiochemotherapy in locally advanced rectal cancer measured by PET/CT Int J Colorectal Dis 24 191 200 10.1007/s00384-008- 0616-8 19050900
23. AM Mandard F Dalibard JC Mandard, et al. 1994 Pathologic assessment of tumor regression after preoperative CRT of esophageal carcinoma. Clinicopathologic correlations Cancer 73 2680 2686 1:STN:280: DyaK2c3ltFOjsA%3D%3D 10.1002/1097-0142(19940601)73:11<2680::AID- CNCR2820731105>3.0.CO;2-C 8194005 (Pubitemid 24166250)
24. Z Wang Z Zhou C Wang, et al. 2005 Microscopic spread of low rectal cancer in regions of the mesorectum: detailed pathological assessment with whole-mount sections Int J Colorectal Dis 20 231 237 1:CAS:528:DC%2BD28XhtF2is70%3D 10.1007/s00384-004-0674-5 15614503 (Pubitemid 40553001)
25. FM Vecchio V Valentini BD Minsky 2005 The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer Int J Radiat Oncol Biol Phys 62 752 760 10.1016/j.ijrobp.2004.11.017 15936556 (Pubitemid 40779765)
26. Sobin L, Gospodarowicz M, Wittekind C (eds) (2009) International union against cancer: TNM classification of malignant tumors, 7th edn. New York: Wiley/Blackwell
27. M Mohiuddin WF Regine J Marks, et al. 1998 High-dose preoperative radiation and the challenge of a sphincter-preservation surgery for cancer of the distal 2 cm of the rectum Int J Radiat Oncol Biol Phys 40 569 574 1:STN:280:DyaK1c7ks1Sisw%3D%3D 10.1016/S0360-3016(97)00842-0 9486606 (Pubitemid 28104226)
28. V Valentini C Coco N Cellini 2001 Ten years of preoperative chemoradiation for extraperitoneal T3 rectal cancer. Acute toxicity, tumor response and sphincter preservation in three consecutive studies Int J Radiat Oncol Biol Phys 51 371 383 1:STN:280:DC%2BD3Mrit1SktQ%3D%3D 11567811 (Pubitemid 32884284)
29. PF Kao YH Chou CW Lai 2008 Diffuse FDG uptake in acute prostatitis Clin Nucl Med 33 308 310 10.1097/RLU.0b013e3181662f8b 18356681 (Pubitemid 351450699)
30. K Becker JD Mueller C Schumacher, et al. 2003 Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy Cancer 98 1521 1530 10.1002/cncr.11660 14508841 (Pubitemid 37151509)