Mechanisms of tumor growth retardation by modulation of pH regulation in the tumor-microenvironment of a murine T cell lymphoma

Biomedicine and Pharmacotherapy

Volumn 65, Issue 1, 2011, Pages 27-39

  Vishvakarma, Naveen Kumar ^a   Singh, Sukh Mahendra ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

Apoptosis; Pantoprazole; Tumor retardation

Indexed keywords

CAD PROTEIN; GAMMA INTERFERON; GLUCOSE TRANSPORTER; HEAT SHOCK PROTEIN 70; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 10; INTERLEUKIN 4; INTERLEUKIN 6; L SELECTIN; PANTOPRAZOLE; PROTEIN BCL 2; PROTEIN P53; PUMA PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING; SUPPRESSOR OF CYTOKINE SIGNALING 5; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; PROTEIN EXPRESSION; T CELL LYMPHOMA; TUMOR CELL; TUMOR GROWTH; TUMOR MICROENVIRONMENT;

2-PYRIDINYLMETHYLSULFINYLBENZIMIDAZOLES; ANIMALS; APOPTOSIS; ASCITIC FLUID; CELL SURVIVAL; DISEASE PROGRESSION; FEMALE; HYDROGEN-ION CONCENTRATION; LYMPHOMA, T-CELL; MICE; MICE, INBRED BALB C; PROTON PUMP INHIBITORS;

EID: 79951674887     PISSN: 07533322     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopha.2010.06.012     Document Type: Article

References (55)

1. Cairns R., Papandreou I., Denko N. Overcoming physiologic barriers to cancer treatment by molecularly targeting the tumor microenvironment. Mol Cancer Res 2006, 4:61-70.
2. Sennoune S.R., Martinez-Zaguilan R. Plasmalemmal vacuolar H+-ATPases in angiogenesis, diabetes and cancer. J Bioenerg Biomembr 2007, 39:427-433.
3. Chiche J., Ilc K., Laferriere J., Trottier E., Dayan F., Mazure N.M., et al. Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell growth by counteracting acidosis through the regulation of the intracellular pH. Cancer Res 2009, 69:358-368.
4. Brett S. Science review: the use of proton pump inhibitors for gastric acid suppression in critical illness. Crit Care 2005, 9:45-50.
5. Chen M., Zou X., Luo H., Cao J., Zhang X., Zhang B., et al. Effects and mechanisms of proton pump inhibitors as a novel chemosensitizer on human gastric adenocarcinoma (SGC7901) cells. Cell Biol Int 2009, 33:1008-1019.
6. Morimura T., Fujita K., Akita M., Nagashima M., Satomi A. The proton pump inhibitor inhibits cell growth and induces apoptosis in human hepatoblastoma. Pediatr Surg Int 2008, 24:1087-1094.
7. Scaringi L., Cornacchione P., Ayroldi E., Corazzi L., Capodicasa E., Rossi R., et al. Omeprazole induces apoptosis in jurkat cells. Int J Immunopathol Pharmacol 2004, 17:331-342.
8. De Milito A., Iessi E., Logozzi M., Lozupone F., Spada M., Marino M.L., et al. Proton pump inhibitors induce apoptosis of human B-cell tumors through a caspase-independent mechanism involving reactive oxygen species. Cancer Res 2007, 67:5408-5417.
9. Luciani F., Spada M., De Milito A., Molinari A., Rivoltini L., Montinaro A., et al. Effect of proton pump inhibitor pretreatment on resistance of solid tumors to cytotoxic drugs. J Natl Cancer Inst 2004, 96:1702-1713.
10. Basu D., Herlyn M. Defining microenvironments within mouse models that enhance tumor aggressiveness. Cancer Biol Ther 2009, 8:380-381.
11. Garcia Rodriguez L.A., Lagergren J., Lindblad M. Gastric acid suppression and risk of oesophageal and gastric adenocarcinoma: a nested case control study in the UK. Gut 2006, 55:1538-1544.
12. Viste A., Ovrebo K., Maartmann-Moe H., Waldum H. Lanzoprazole promotes gastric carcinogenesis in rats with duodenogastric reflux. Gastric Cancer 2004, 7:31-35.
13. Dammann H.G., Burkhardt F. Pantoprazole versus omeprazole: influence on meal-stimulated gastric acid secretion. Eur J Gastroenterol Hepatol 1999, 11:1277-1282.
14. Horn J. The proton-pump inhibitors: similarities and differences. Clin Ther 2000, 22(266-80). [discussion 5].
15. Nishioka K., Nagao T., Urushidani T. Correlation between acid secretion and proton pump activity during inhibition by the proton pump inhibitors omeprazole and pantoprazole. Biochem Pharmacol 1999, 58:1349-1359.
16. Cortes J.R., Rivas M.D., Molina-Infante J., Gonzalez-Nunez M.A., Perez G.M., Masa J.F., et al. Omeprazole inhibits IL-4 and IL-13 signaling signal transducer and activator of transcription 6 activation and reduces lung inflammation in murine asthma. J Allergy Clin Immunol 2009, 124(607-10). [10 e1].
17. Sulkowska M., Wincewicz A., Sulkowski S., Koda M., Kanczuga-Koda L. Relations of TGF-beta1 with HIF-1 alpha, GLUT-1 and longer survival of colorectal cancer patients. Pathology 2009, 41:254-260.
18. Bharti A.C., Singh S.M. Inhibition of macrophage nitric oxide production by gangliosides derived from a spontaneous T cell lymphoma: the involved mechanisms. Nitric Oxide 2003, 8:75-82.
19. Singh M.P., Singh G., Singh S.M. Paraneoplastic neurodegeneration in a murine host following progressive growth of a spontaneous T-Cell lymphoma: role of proinflammatory internal responses. Neuroimmunomodulation 2006, 13:122-132.
20. Gupta V., Singh S.M. Gender dimorphism in the myeloid differentiation of bone marrow precursor cells in a murine host bearing a T cell lymphoma. J Reprod Immunol 2007, 74:90-102.
21. Gupta V., Singh S.M. Sex dimorphism in antitumor response of chemotherapeutic drug cisplatin in a murine host-bearing a T-cell lymphoma. Anticancer Drugs 2008, 19:583-592.
22. Gupta V., Singh S.M. Gender dimorphism of macrophage response to GMCSF and IL-4 for differentiation into dendritic cells. Am J Reprod Immunol 2008, 60:43-54.
23. Singh V., Singh S.M. Progressive tumor growth-associated altered tumor microenvironment: implications in a tumor stage-dependent modulation in survival of a murine T cell lymphoma. J Cancer Res Clin Oncol 2009, 135:1015-1024.
24. Singh V., Singh S.M. A tumour stage-dependent evolution of drug resistant T cell lymphoma: role of soluble mediators of tumour and host origin. Leuk Res 2009, 33:700-709.
25. Singh V., Singh M.P., Singh S.M. Cell density-dependent alterations in tumorigenic potential of a murine T-cell lymphoma: implication in the evolution of multidrug resistance in tumor cells. Anticancer Drugs 2008, 19:793-804.
26. Singh V., Singh S.M. Effect of high cell density on the growth properties of tumor cells: a role in tumor cytotoxicity of chemotherapeutic drugs. Anticancer Drugs 2007, 18:1123-1132.
27. Shanker A., Singh S.M., Sodhi A. Impairment of T-cell functions with the progressive ascitic growth of a transplantable T-cell lymphoma of spontaneous origin. FEMS Immunol Med Microbiol 2000, 27:247-255.
28. Ben-Efraim S. One hundred years of cancer immunotherapy: a critical appraisal. Tumour Biol 1999, 20:1-24.
29. Singh M.P., Singh G., Singh S.M. Role of host's antitumor immunity in exercise-dependent regression of murine T-cell lymphoma. Comp Immunol Micro Infect Dis 2005, 28:231-248.
30. Zhang G., Gurtu V., Kain S.R., Yan G. Early detection of apoptosis using a fluorescent conjugate of annexin V. Biotechniques 1997, 23:525-531.
31. Sellins K.S., Cohen J.J. Gene induction by gamma-irradiation leads to DNA fragmentation in lymphocytes. J Immunol 1987, 139:3199-3206.
32. Osborn M. Immunofluorescence microscopy of cultured cells. Cell Biology: A laboratory handbook 1994, 347-360. Academic Press.
33. Ding A.H., Nathan C.F., Stuehr D.J. J Immunol. Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production 1988, 141:2407-2412.
34. Chaudhuri R.K., Mukherjee M., Sengupta D., Mazumder S. Limitation of glucose oxidase method of glucose estimation in jaundiced neonates. Indian J Exp Biol 2006, 44:254-255.
35. Somoza B., Guzman R., Cano V., Merino B., Ramos P., Diez-Fernandez C., et al. Induction of cardiac uncoupling protein-2 expression and adenosine 5'-monophosphate-activated protein kinase phosphorylation during early states of diet-induced obesity in mice. Endocrinology 2007, 148:924-931.
36. Golomzik A.I., Kovalenko K.P., Briantsev I.A.V. [Modification of Winkler's method for assay of dissolved oxygen in acid solutions]. Mikrobiologiia 1967, 36:355-360.
37. Casciari J.J., Sotirchos S.V., Sutherland R.M. Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration, and extracellular pH. J Cell Physiol 1992, 151:386-394.
38. Thibault R., De Coppet P., Bourreille A., Cuff M., Bonnet C., et al. Down-regulation of the monocarboxylate transporter 1 is involved in butyrate deficiency during intestinal inflammation. Gastroenterology 2007, 133:1916-1927.
39. Yamagata K., Tagami M., Yamori Y. Nitric oxide reduces astrocytic lactate production and induces neuronal vulnerability in stroke-prone spontaneously hypertensive rats. Glia 2008, 56:387-393.
40. Lopez-Lazaro M. HIF-1: hypoxia-inducible factor or dysoxia-inducible factor?. FASEB J 2006, 20:828-832.
41. Marin-Hernandez A., Gallardo-Perez J.C., Ralph S.J., Rodriguez-Enriquez S., Moreno-Sanchez R. HIF-1alpha modulates energy metabolism in cancer cells by inducing over-expression of specific glycolytic isoforms. Mini Rev Med Chem 2009, 9:1084-1101.
42. Nishi H., Nakada T., Hokamura M., Osakabe Y., Itokazu O., Huang L.E., et al. Hypoxia-inducible factor-1 transactivates transforming growth factor-beta3 in trophoblast. Endocrinology 2004, 145:4113-4118.
43. Watanabe H., Bohensky J., Freeman T., Srinivas V., Shapiro I.M. Hypoxic induction of UCP3 in the growth plate: UCP3 suppresses chondrocyte autophagy. J Cell Physiol 2008, 216:419-425.
44. Dunn L.K., Mohammad K.S., Fournier P.G., McKenna C.R., Davis H.W., Niewolna M., et al. Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment. PLoS One 2009, 4:e6896.
45. Park Y.H., Sohn S.K., Kim J.G., Lee M.H., Song H.S., Kim M.K., et al. Interaction between BCL2 and interleukin-10 gene polymorphisms alter outcomes of diffuse large B-cell lymphoma following rituximab plus CHOP chemotherapy. Clin Cancer Res 2009, 15:2107-2115.
46. Sanchez-Elsner T., Botella L.M., Velasco B., Corbi A., Attisano L., Bernabeu C. Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression. J Biol Chem 2001, 276:38527-38535.
47. Trisciuoglio D., Iervolino A., Zupi G., Del Bufalo D. Involvement of PI3K and MAPK signaling in bcl-2-induced vascular endothelial growth factor expression in melanoma cells. Mol Biol Cell 2005, 16:4153-4162.
48. Contasta I., Berghella A.M., Pellegrini P., Adorno D. Passage from normal mucosa to adenoma and colon cancer: alteration of normal sCD30 mechanisms regulating TH1/TH2 cell functions. Cancer Biother Radiopharm 2003, 18:549-557.
49. Klausen P., Pedersen L., Jurlander J., Baumann H. Oncostatin M and interleukin 6 inhibit cell cycle progression by prevention of p27kip1 degradation in HepG2 cells. Oncogene 2000, 19:3675-3683.
50. Hong J., Nakano Y., Yokomakura A., Ishihara K., Kim S., Kang Y.S., et al. Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells. J Pharmacol Exp Ther 2006, 319:672-681.
51. Wang P., Qiu W., Dudgeon C., Liu H., Huang C., Zambetti G.P., et al. PUMA is directly activated by NF-kappaB and contributes to TNF-alpha-induced apoptosis. Cell Death Differ 2009, 16:1192-1202.
52. Morita Y., Naka T., Kawazoe Y., Fujimoto M., Narazaki M., Nakagawa R., et al. Signals transducers and activators of transcription (STAT)-induced STAT inhibitor-1 (SSI-1)/suppressor of cytokine signaling-1 (SOCS-1) suppresses tumor necrosis factor alpha-induced cell death in fibroblasts. Proc Natl Acad Sci U S A 2000, 97:5405-5410.
53. Belanger S.D., St-Pierre Y. Role of selectins in the triggering, growth, and dissemination of T-lymphoma cells: implication of l-selectin in the growth of thymic lymphoma. Blood 2005, 105:4800-4806.
54. Kanegane H., Kasahara Y., Niida Y., Yachie A., Sughii S., Takatsu K., et al. Expression of l-selectin (CD62L) discriminates Th1- and Th2-like cytokine-producing memory CD4+ T cells. Immunology 1996, 87:186-190.
55. Sparrow R.L., Komodromou H., Tippett E., Georgakopoulos T., Xu W. Apoptotic lymphocytes and CD34+ cells in cryopreserved cord blood detected by the fluorescent vital dye SYTO 16 and correlation with loss of l-selectin (CD62L) expression. Bone Marrow Transplant 2006, 38:61-67.