-
1
-
-
77952367661
-
Comprehen-sive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition
-
Carvajal-Carmona LG, Churchman M, Bonilla C, Walther A, Lefevre JH, Kerr D, Dunlop M, Houlston R, Bodmer WF, Tomlinson I. Comprehen-sive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition. Proc Natl Acad Sci USA (2010); 107: 7858-7862
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 7858-7862
-
-
Carvajal-Carmona, L.G.1
Churchman, M.2
Bonilla, C.3
Walther, A.4
Lefevre, J.H.5
Kerr, D.6
Dunlop, M.7
Houlston, R.8
Bodmer, W.F.9
Tomlinson, I.10
-
2
-
-
42449136232
-
Allelic imbalance in BRCA1 and BRCA2 gene expression is associated with an increased breast cancer risk
-
DOI 10.1093/hmg/ddn022
-
Chen X, Weaver J, Bove BA, Vanderveer LA, Weil SC, Miron A, Daly MB, Godwin AK (2008) Allelic imbalance in BRCA1 and BRCA2 gene expression is associated with an increased breast cancer risk. Hum Mol Genet 17: 1336-1348 (Pubitemid 351566970)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.9
, pp. 1336-1348
-
-
Chen, X.1
Weaver, J.2
Bove, B.A.3
Vanderveer, L.A.4
Weil, S.C.5
Miron, A.6
Daly, M.B.7
Godwin, A.K.8
-
3
-
-
0036843938
-
Detection of regulatory variation in mouse genes
-
DOI 10.1038/ng992
-
Cowles CR, Hirschhorn JN, Altshuler D, Lander ES (2002) Detection of regulatory variation in mouse genes. Nat Genet 32: 432-437 (Pubitemid 35266121)
-
(2002)
Nature Genetics
, vol.32
, Issue.3
, pp. 432-437
-
-
Cowles, C.R.1
Hirschhorn, J.N.2
Altshuler, D.3
Lander, E.S.4
-
4
-
-
4944240144
-
Genetic predisposition to colorectal cancer
-
DOI 10.1038/nrc1453
-
de la Chapelle A (2004) Genetic predisposition to colorectal cancer. Nat Rev Cancer 4: 769-780 (Pubitemid 39331149)
-
(2004)
Nature Reviews Cancer
, vol.4
, Issue.10
, pp. 769-780
-
-
De La Chapelle, A.1
-
5
-
-
67449152486
-
Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients
-
Guda K, Natale L, Lutterbaugh J, Wiesner GL, Lewis S, Tanner SM, Tomsic J, Valle L, de la Chapelle A, Elston RC, Willis J, Markowitz SD (2009) Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients. Cancer Res 69: 4959-4961
-
(2009)
Cancer Res
, vol.69
, pp. 4959-4961
-
-
Guda, K.1
Natale, L.2
Lutterbaugh, J.3
Wiesner, G.L.4
Lewis, S.5
Tanner, S.M.6
Tomsic, J.7
Valle, L.8
De La Chapelle, A.9
Elston, R.C.10
Willis, J.11
Markowitz, S.D.12
-
7
-
-
33744907495
-
Evidence of linkage to chromosome 9q22.33 in colorectal cancer kindreds from the United Kingdom
-
DOI 10.1158/0008-5472.CAN-05-4074
-
Kemp ZE, Carvajal-Carmona LG, Barclay E, Gorman M, Martin L, Wood W, Rowan A, Donohue C, Spain S, Jaeger E, Evans DG, Maher ER, Bishop T, Thomas H, Houlston R, Tomlinson I (2006) Evidence of linkage to chromosome 9q22.33 in colorectal cancer kindreds from the United Kingdom. Cancer Res 66: 5003-5006 (Pubitemid 43844919)
-
(2006)
Cancer Research
, vol.66
, Issue.10
, pp. 5003-5006
-
-
Kemp, Z.E.1
Carvajal-Carmona, L.G.2
Barclay, E.3
Gorman, M.4
Martin, L.5
Wood, W.6
Rowan, A.7
Donohue, C.8
Spain, S.9
Jaeger, E.10
Evans, D.G.11
Maher, E.R.12
Bishop, T.13
Thomas, H.14
Houlston, R.15
Tomlinson, I.16
-
8
-
-
0038079807
-
Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor α, NFKB1, and peroxisome proliferator-activated receptor γ with colorectal cancer
-
Landi S, Moreno V, Gioia-Patricola L, Guino E, Navarro M, de Oca J, Capella G, Canzian F (2003) Association of common polymorphisms in inflammatory genes interleukin (IL)6, IL8, tumor necrosis factor alpha, NFKB1, and peroxisome proliferator-activated receptor gamma with colorectal cancer. Cancer Res 63: 3560-3566 (Pubitemid 36793036)
-
(2003)
Cancer Research
, vol.63
, Issue.13
, pp. 3560-3566
-
-
Landi, S.1
Moreno, V.2
Gioia-Patricola, L.3
Guino, E.4
Navarro, M.5
De Oca, J.6
Capella, G.7
Canzian, F.8
-
9
-
-
67650924286
-
Review of the Lynch syndrome: History, molecular genetics, screening, differential diagnosis, and medicolegal ramifications
-
Lynch HT, Lynch PM, Lanspa SJ, Snyder CL, Lynch JF, Boland CR (2009) Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications. Clin Genet 76: 1-18
-
(2009)
Clin Genet
, vol.76
, pp. 1-18
-
-
Lynch, H.T.1
Lynch, P.M.2
Lanspa, S.J.3
Snyder, C.L.4
Lynch, J.F.5
Boland, C.R.6
-
10
-
-
1442356678
-
TGFBR1*6A and cancer: A meta-analysis of 12 case-control studies
-
Pasche B, Kaklamani V, Hou N, Young T, Rademaker A, Peterlongo P, Ellis N, Offit K, Caldes T, Reiss M, Zheng T (2004) TGFBR1*6A and cancer: a meta-analysis of 12 case-control studies. J Clin Oncol 22: 756-758
-
(2004)
J Clin Oncol
, vol.22
, pp. 756-758
-
-
Pasche, B.1
Kaklamani, V.2
Hou, N.3
Young, T.4
Rademaker, A.5
Peterlongo, P.6
Ellis, N.7
Offit, K.8
Caldes, T.9
Reiss, M.10
Zheng, T.11
-
11
-
-
77957805183
-
Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs
-
Pasche B, Wisinski KB, Sadim M, Kaklamani V, Pennison MJ, Zeng Q, Bellam N, Zimmerman J, Yi N, Zhang K, Baron J, Stram DO, Hayes MG (2010) Constitutively decreased TGFBR1 allelic expression is a common finding in colorectal cancer and is associated with three TGFBR1 SNPs. J Exp Clin Cancer Res 29: 57
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 57
-
-
Pasche, B.1
Wisinski, K.B.2
Sadim, M.3
Kaklamani, V.4
Pennison, M.J.5
Zeng, Q.6
Bellam, N.7
Zimmerman, J.8
Yi, N.9
Zhang, K.10
Baron, J.11
Stram, D.O.12
Hayes, M.G.13
-
12
-
-
19444364509
-
Statins and the risk of colorectal cancer
-
DOI 10.1056/NEJMoa043792
-
Poynter JN, Gruber SB, Higgins PD, Almog R, Bonner JD, Rennert HS, Low M, Greenson JK, Rennert G (2005) Statins and the risk of colorectal cancer. N Engl J Med 352: 2184-2192 (Pubitemid 40727085)
-
(2005)
New England Journal of Medicine
, vol.352
, Issue.21
, pp. 2184-2192
-
-
Poynter, J.N.1
Gruber, S.B.2
Higgins, P.D.R.3
Almog, R.4
Bonner, J.D.5
Rennert, H.S.6
Low, M.7
Greenson, J.K.8
Rennert, G.9
-
13
-
-
34249314024
-
Downregulation of Death-Associated Protein Kinase 1 (DAPK1) in Chronic Lymphocytic Leukemia
-
DOI 10.1016/j.cell.2007.03.043, PII S0092867407005120
-
Raval A, Tanner SM, Byrd JC, Angerman EB, Perko JD, Chen SS, Hackanson B, Grever MR, Lucas DM, Matkovic JJ, Lin TS, Kipps TJ, Murray F, Weisenburger D, Sanger W, Lynch J, Watson P, Jansen M, Yoshinaga Y, Rosenquist R, de Jong PJ, Coggill P, Beck S, Lynch H, de la Chapelle A, Plass C (2007) Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia. Cell 129: 879-890 (Pubitemid 46813150)
-
(2007)
Cell
, vol.129
, Issue.5
, pp. 879-890
-
-
Raval, A.1
Tanner, S.M.2
Byrd, J.C.3
Angerman, E.B.4
Perko, J.D.5
Chen, S.-S.6
Hackanson, B.7
Grever, M.R.8
Lucas, D.M.9
Matkovic, J.J.10
Lin, T.S.11
Kipps, T.J.12
Murray, F.13
Weisenburger, D.14
Sanger, W.15
Lynch, J.16
Watson, P.17
Jansen, M.18
Yoshinaga, Y.19
Rosenquist, R.20
De Jong, P.J.21
Coggill, P.22
Beck, S.23
Lynch, H.24
De La Chapelle, A.25
Plass, C.26
more..
-
14
-
-
33746905921
-
Linkage analysis in a large Swedish family supports the presence of a susceptibility locus for adenoma and colorectal cancer on chromosome 9q22.32-31.1
-
Skoglund J, Djureinovic T, Zhou XL, Vandrovcova J, Renkonen E, Iselius L, Bisgaard ML, Peltomaki P, Lindblom A (2006) Linkage analysis in a large Swedish family supports the presence of a susceptibility locus for adenoma and colorectal cancer on chromosome 9q22.32-31.1. J Med Genet 43: e7
-
(2006)
J Med Genet
, vol.43
-
-
Skoglund, J.1
Djureinovic, T.2
Zhou, X.L.3
Vandrovcova, J.4
Renkonen, E.5
Iselius, L.6
Bisgaard, M.L.7
Peltomaki, P.8
Lindblom, A.9
-
15
-
-
34250759902
-
Lack of an association between the TGFBR1*6A variant and colorectal cancer risk
-
DOI 10.1158/1078-0432.CCR-06-2865
-
Skoglund J, Song B, Dalen J, Dedorson S, Edler D, Hjern F, Holm J, Lenander C, Lindforss U, Lundqvist N, Olivecrona H, Olsson L, Pahlman L, Rutegard J, Smedh K, Tornqvist A, Houlston RS, Lindblom A (2007) Lack of an association between the TGFBR1*6A variant and colorectal cancer risk. Clin Cancer Res 13: 3748-3752 (Pubitemid 46955140)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.12
, pp. 3748-3752
-
-
Skoglund, J.1
Song, B.2
Dalen, J.3
Dedorson, S.4
Edler, D.5
Hjern, F.6
Holm, J.7
Lenander, C.8
Lindforss, U.9
Lundqvist, N.10
Olivecrona, H.11
Olsson, L.12
Pahlman, L.13
Rutegard, J.14
Smedh, K.15
Tornqvist, A.16
Houlston, R.S.17
Lindblom, A.18
-
16
-
-
77957799874
-
Allele-specific expression of TGFBR1 in colon cancer patients
-
Tomsic J, Guda K, Liyanarachchi S, Hampel H, Natale L, Markowitz SD, Tanner SM, de la Chapelle A. Allele-specific expression of TGFBR1 in colon cancer patients. Carcinogenesis (2010); 31(10): 1800-1804
-
(2010)
Carcinogenesis
, vol.31
, Issue.10
, pp. 1800-1804
-
-
Tomsic, J.1
Guda, K.2
Liyanarachchi, S.3
Hampel, H.4
Natale, L.5
Markowitz, S.D.6
Tanner, S.M.7
De La Chapelle, A.8
-
17
-
-
51149099981
-
Germline allele-specific expression ofTGFBR1 confers an increased risk of colorectal cancer
-
Valle L, Serena-Acedo T, Liyanarachchi S, Hampel H, Comeras I, Li Z, Zeng Q, Zhang HT, Pennison MJ, Sadim M, Pasche B, Tanner SM, de la Chapelle A (2008) Germline allele-specific expression ofTGFBR1 confers an increased risk of colorectal cancer. Science 321: 1361-1365
-
(2008)
Science
, vol.321
, pp. 1361-1365
-
-
Valle, L.1
Serena-Acedo, T.2
Liyanarachchi, S.3
Hampel, H.4
Comeras, I.5
Li, Z.6
Zeng, Q.7
Zhang, H.T.8
Pennison, M.J.9
Sadim, M.10
Pasche, B.11
Tanner, S.M.12
De La Chapelle, A.13
-
18
-
-
0242363139
-
A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2
-
DOI 10.1073/pnas.2132286100
-
Wiesner GL, Daley D, Lewis S, Ticknor C, Platzer P, Lutterbaugh J, MacMillen M, Baliner B, Willis J, Elston RC, Markowitz SD (2003) A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2. Proc Natl Acad Sci USA 100: 12961-12965 (Pubitemid 37340008)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.22
, pp. 12961-12965
-
-
Wiesner, G.L.1
Daley, D.2
Lewis, S.3
Ticknor, C.4
Platzer, P.5
Lutterbaugh, J.6
MacMillen, M.7
Baliner, B.8
Willis, J.9
Elston, R.C.10
Markowitz, S.D.11
-
19
-
-
34047129806
-
Extreme context specificity in differential allelic expression
-
DOI 10.1093/hmg/ddl488
-
Wilkins JM, Southam L, Price AJ, Mustafa Z, Carr A, Loughlin J (2007) Extreme context specificity in differential allelic expression. Hum Mol Genet 16: 537-546 (Pubitemid 46522616)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.5
, pp. 537-546
-
-
Wilkins, J.M.1
Southam, L.2
Price, A.J.3
Mustafa, Z.4
Carr, A.5
Loughlin, J.6
-
20
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
DOI 10.1126/science.1145720
-
Wood LD, Parsons DW, Jones S, Lin J, Sjoblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, Nikolsky Y, Karchin R, Wilson PA, Kaminker JS, Zhang Z, Croshaw R, Willis J, Dawson D, Shipitsin M, Willson JK, Sukumar S, Polyak K, Park BH, Pethiyagoda CL, Pant PV, Ballinger DG, Sparks AB, Hartigan J, Smith DR, Suh E, Papadopoulos N, Buckhaults P, Markowitz SD, Parmigiani G, Kinzler KW, Velculescu VE, Vogelstein B (2007) The genomic landscapes of human breast and colorectal cancers. Science 318: 1108-1113 (Pubitemid 350134889)
-
(2007)
Science
, vol.318
, Issue.5853
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
Lin, J.4
Sjoblom, T.5
Leary, R.J.6
Shen, D.7
Boca, S.M.8
Barber, T.9
Ptak, J.10
Silliman, N.11
Szabo, S.12
Dezso, Z.13
Ustyanksky, V.14
Nikolskaya, T.15
Nikolsky, Y.16
Karchin, R.17
Wilson, P.A.18
Kaminker, J.S.19
Zhang, Z.20
Croshaw, R.21
Willis, J.22
Dawson, D.23
Shipitsin, M.24
Willson, J.K.V.25
Sukumar, S.26
Polyak, K.27
Ben, H.P.28
Pethiyagoda, C.L.29
Pant, P.V.K.30
Ballinger, D.G.31
Sparks, A.B.32
Hartigan, J.33
Smith, D.R.34
Suh, E.35
Papadopoulos, N.36
Buckhaults, P.37
Markowitz, S.D.38
Parmigiani, G.39
Kinzler, K.W.40
Velculescu, V.E.41
Vogelstein, B.42
more..
-
21
-
-
0036334007
-
Small changes in expression affect predisposition to tumorigenesis
-
Yan H, Dobbie Z, Gruber SB, Markowitz S, Romans K, Giardiello FM, Kinzler KW, Vogelstein B (2002) Small changes in expression affect predisposition to tumorigenesis. Nat Genet 30: 25-26
-
(2002)
Nat Genet
, vol.30
, pp. 25-26
-
-
Yan, H.1
Dobbie, Z.2
Gruber, S.B.3
Markowitz, S.4
Romans, K.5
Giardiello, F.M.6
Kinzler, K.W.7
Vogelstein, B.8
-
22
-
-
58349120416
-
Tgfbr1 haploinsufficiency is a potent modifier ofcolorectal cancer development
-
Zeng Q, Phukan S, Xu Y, Sadim M, Rosman DS, Pennison M, Liao J, Yang GY, Huang CC, Valle L, Di Cristofano A, de la Chapelle A, Pasche B (2009) Tgfbr1 haploinsufficiency is a potent modifier ofcolorectal cancer development. Cancer Res 69: 678-686
-
(2009)
Cancer Res
, vol.69
, pp. 678-686
-
-
Zeng, Q.1
Phukan, S.2
Xu, Y.3
Sadim, M.4
Rosman, D.S.5
Pennison, M.6
Liao, J.7
Yang, G.Y.8
Huang, C.C.9
Valle, L.10
Di Cristofano, A.11
De La Chapelle, A.12
Pasche, B.13
|