Iron loading-induced aggregation and reduction of iron incorporation in heteropolymeric ferritin containing a mutant light chain that causes neurodegeneration

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1812, Issue 4, 2011, Pages 544-548

  Muhoberac, Barry B ^a,c   Baraibar, Martin A ^b   Vidal, Ruben ^b  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Department of Chemistry and Chemical Biology ^*  (United States)

Author keywords

Ferritin; Hereditary ferritinopathy; Iron; Neurodegeneration; Pore

Indexed keywords

APOFERRITIN; FERRITIN; HETEROPOLYMERIC FERRITIN; IRON; PHENYLALANINE; POLYMER; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; HEAVY CHAIN; HEREDITARY FERRITINOPATHY; HUMAN; IRON OVERLOAD; LIGHT CHAIN; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN STRUCTURE; WILD TYPE;

APOFERRITINS; CHEMICAL PRECIPITATION; FERRITINS; HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM; HUMANS; IRON; MUTATION; NERVE DEGENERATION; POLYMERIZATION; SOLUBILITY;

EID: 79951671438     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2010.10.010     Document Type: Article

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