Pegylated interferon alpha targets Wnt signaling by inducing nuclear export of β-catenin

Journal of Hepatology

Volumn 54, Issue 3, 2011, Pages 506-512

  Thompson, Michael D ^a   Dar, Mohd Jamal ^a   Monga, Satdarshan P S ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Hepatocellular cancer; Interferon; Liver cancer; Proliferation; Ran binding protein 3 (RanBP3); Treatment; Wnt

Indexed keywords

BETA CATENIN; CYCLIN D1; GLUTAMATE AMMONIA LIGASE; JANUS KINASE; MESSENGER RNA; NUCLEAR PROTEIN; PEGINTERFERON; PEGYLATED INTERFERON ALPHA; PROTEIN RANBP3; STAT PROTEIN; T CELL FACTOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CYTOPLASM; DRUG EFFECT; DRUG TARGETING; GENE EXPRESSION; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; ANTIVIRAL AGENTS; BETA CATENIN; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; GENE KNOCKDOWN TECHNIQUES; HEP G2 CELLS; HEPATITIS C, CHRONIC; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERFERON-ALPHA; LIVER; LIVER NEOPLASMS; MICE; MICE, TRANSGENIC; MUTANT PROTEINS; NUCLEAR PROTEINS; NUCLEOCYTOPLASMIC TRANSPORT PROTEINS; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; WNT PROTEINS;

EID: 79951670840     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.07.020     Document Type: Article

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