메뉴 건너뛰기




Volumn 26, Issue 3, 2011, Pages 461-468

Hepatitis B virus genotype B results in better immediate, late and sustained responses to peginterferon-alfa in hepatitis-B-e-antigen-positive patients

Author keywords

HBV genotype; Hepatitis B virus; Peginterferon; Precore mutation

Indexed keywords

ALANINE AMINOTRANSFERASE; ENTECAVIR; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; PEGINTERFERON ALPHA2A; TELBIVUDINE;

EID: 79951660421     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/j.1440-1746.2010.06429.x     Document Type: Article
Times cited : (19)

References (41)
  • 2
    • 0027422748 scopus 로고
    • From hepatitis to hepatoma: lessons from type B viral hepatitis
    • Chen DS. From hepatitis to hepatoma: lessons from type B viral hepatitis. Science 1993; 262: 369-70.
    • (1993) Science , vol.262 , pp. 369-370
    • Chen, D.S.1
  • 3
    • 0030782535 scopus 로고    scopus 로고
    • Natural history of chronic hepatitis B virus infection: an immunopathological study
    • Chu CM, Liaw YF. Natural history of chronic hepatitis B virus infection: an immunopathological study. J. Gastroenterol. Hepatol. 1997; 12: S218-S22.
    • (1997) J. Gastroenterol. Hepatol. , vol.12
    • Chu, C.M.1    Liaw, Y.F.2
  • 4
    • 0033214863 scopus 로고    scopus 로고
    • Age, gender, and local geographic variations of viral etiology of hepatocellular carcinoma in a hyperendemic area for hepatitis B virus infection
    • Lee CM, Lu SN, Changchien CS etal. Age, gender, and local geographic variations of viral etiology of hepatocellular carcinoma in a hyperendemic area for hepatitis B virus infection. Cancer 1999; 86: 1143-50.
    • (1999) Cancer , vol.86 , pp. 1143-1150
    • Lee, C.M.1    Lu, S.N.2    Changchien, C.S.3
  • 5
    • 0022644109 scopus 로고
    • Clinical, virologic and histologic outcome following seroconversion from HBeAg to anti-HBe in chronic hepatitis type B
    • Fattovich G, Rugge M, Brollo L etal. Clinical, virologic and histologic outcome following seroconversion from HBeAg to anti-HBe in chronic hepatitis type B. Hepatology 1986; 6: 167-72.
    • (1986) Hepatology , vol.6 , pp. 167-172
    • Fattovich, G.1    Rugge, M.2    Brollo, L.3
  • 6
    • 0029893146 scopus 로고    scopus 로고
    • Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B
    • Niederau C, Heintges T, Lange S etal. Long-term follow-up of HBeAg-positive patients treated with interferon alfa for chronic hepatitis B. N. Engl. J. Med. 1996; 334: 1422-7.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1422-1427
    • Niederau, C.1    Heintges, T.2    Lange, S.3
  • 7
    • 0030696048 scopus 로고    scopus 로고
    • Long-term outcome of hepatitis B e antigen-positive patients with compensated cirrhosis treated with interferon alfa
    • Fattovich G, Giustina G, Realdi G etal. Long-term outcome of hepatitis B e antigen-positive patients with compensated cirrhosis treated with interferon alfa. Hepatology 1997; 26: 1338-42.
    • (1997) Hepatology , vol.26 , pp. 1338-1342
    • Fattovich, G.1    Giustina, G.2    Realdi, G.3
  • 8
    • 21244447705 scopus 로고    scopus 로고
    • Peginterferon alfa-2a, lamivudine and the combination for HBeAg-positive chronic hepatitis B
    • Lau GKK, Piratvisuth T, Luo KX etal. Peginterferon alfa-2a, lamivudine and the combination for HBeAg-positive chronic hepatitis B. N. Engl. J. Med. 2005; 352: 2682-95.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 2682-2695
    • Lau, G.K.K.1    Piratvisuth, T.2    Luo, K.X.3
  • 9
    • 19944428132 scopus 로고    scopus 로고
    • Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomized trial
    • Janssen HL, van Zonneveld M, Senturk H etal. Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomized trial. Lancet 2005; 365: 123-29.
    • (2005) Lancet , vol.365 , pp. 123-129
    • Janssen, H.L.1    van Zonneveld, M.2    Senturk, H.3
  • 10
    • 0024448926 scopus 로고
    • Which patients with chronic hepatitis B virus infection will respond to alpha-interferon therapy? A statistical analysis of predictive factors
    • Brook MG, Karayiannis P, Thomas HC. Which patients with chronic hepatitis B virus infection will respond to alpha-interferon therapy? A statistical analysis of predictive factors. Hepatology 1989; 10: 761-3.
    • (1989) Hepatology , vol.10 , pp. 761-763
    • Brook, M.G.1    Karayiannis, P.2    Thomas, H.C.3
  • 11
    • 0025347975 scopus 로고
    • A randomized, controlled trial of interferon alfa-2b alone and after prednisone withdrawal for the treatment of chronic hepatitis B. The Hepatitis Interventional Therapy Group
    • Perrillo RP, Schiff ER, Davis GL etal. A randomized, controlled trial of interferon alfa-2b alone and after prednisone withdrawal for the treatment of chronic hepatitis B. The Hepatitis Interventional Therapy Group. N. Engl. J.Med. 1990; 323: 295-301.
    • (1990) N. Engl. J.Med. , vol.323 , pp. 295-301
    • Perrillo, R.P.1    Schiff, E.R.2    Davis, G.L.3
  • 12
    • 0026602420 scopus 로고
    • A controlled trial of interferon with or without prednisone priming for chronic hepatitis B
    • Lok AS, Wu PC, Lai CL etal. A controlled trial of interferon with or without prednisone priming for chronic hepatitis B. Gastroenterology 1992; 102: 2091-7.
    • (1992) Gastroenterology , vol.102 , pp. 2091-2097
    • Lok, A.S.1    Wu, P.C.2    Lai, C.L.3
  • 13
    • 0037260187 scopus 로고    scopus 로고
    • Prevalence of clinical implications of hepatitis B virus genotypes in southern Taiwan
    • Lee CM, Chen CH, Lu SN etal. Prevalence of clinical implications of hepatitis B virus genotypes in southern Taiwan. Scand J. Gastroenterol. 2003; 38: 95-101.
    • (2003) Scand J. Gastroenterol. , vol.38 , pp. 95-101
    • Lee, C.M.1    Chen, C.H.2    Lu, S.N.3
  • 14
    • 84984535720 scopus 로고    scopus 로고
    • Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B
    • Kao JH, Chen PJ, Lai MY, Chen DS. Hepatitis B genotypes correlate with clinical outcomes in patients with chronic hepatitis B. Gastroenterology 2000; 118: 554-9.
    • (2000) Gastroenterology , vol.118 , pp. 554-559
    • Kao, J.H.1    Chen, P.J.2    Lai, M.Y.3    Chen, D.S.4
  • 15
    • 84983726628 scopus 로고    scopus 로고
    • Hepatitis B genotypes and the response to interferon therapy
    • Kao JH, Wu NH, Chen PJ, Lai MY, Chen DS. Hepatitis B genotypes and the response to interferon therapy. J. Hepatol. 2000; 33: 998-1002.
    • (2000) J. Hepatol. , vol.33 , pp. 998-1002
    • Kao, J.H.1    Wu, N.H.2    Chen, P.J.3    Lai, M.Y.4    Chen, D.S.5
  • 16
    • 0036896130 scopus 로고    scopus 로고
    • HBV genotype B is associated with better response to interferon therapy in HBeAg (+) chronic hepatitis than genotype C
    • Wai CT, Chu CJ, Hussain M, Lok ASF. HBV genotype B is associated with better response to interferon therapy in HBeAg (+) chronic hepatitis than genotype C. Hepatology 2002; 36: 1425-30.
    • (2002) Hepatology , vol.36 , pp. 1425-1430
    • Wai, C.T.1    Chu, C.J.2    Hussain, M.3    Lok, A.S.F.4
  • 17
    • 0024427902 scopus 로고
    • Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection
    • Carman WF, Jacyna MR, Hadziyannis S etal. Mutation preventing formation of hepatitis B e antigen in patients with chronic hepatitis B infection. Lancet 1989; 2: 588-91.
    • (1989) Lancet , vol.2 , pp. 588-591
    • Carman, W.F.1    Jacyna, M.R.2    Hadziyannis, S.3
  • 18
    • 0025729803 scopus 로고
    • Wild-type and e antigen-minus hepatitis B viruses and course of chronic hepatitis
    • Brunetto MR, Giarin MM, Oliveri F etal. Wild-type and e antigen-minus hepatitis B viruses and course of chronic hepatitis. Proc. Natl. Acad. Sci. U S A. 1991; 88: 4186-90.
    • (1991) Proc. Natl. Acad. Sci. U S A. , vol.88 , pp. 4186-4190
    • Brunetto, M.R.1    Giarin, M.M.2    Oliveri, F.3
  • 19
    • 0025012035 scopus 로고
    • Chronic active hepatitis with hepatitis B virus DNA and antibody against e antigen in the serum. Disturbed synthesis and secretion of e antigen from hepatocytes due to a point mutation in the precore region
    • Akahane Y, Yamanaka T, Suzuki H etal. Chronic active hepatitis with hepatitis B virus DNA and antibody against e antigen in the serum. Disturbed synthesis and secretion of e antigen from hepatocytes due to a point mutation in the precore region. Gastroenterology 1990; 99: 1113-9.
    • (1990) Gastroenterology , vol.99 , pp. 1113-1119
    • Akahane, Y.1    Yamanaka, T.2    Suzuki, H.3
  • 20
    • 0027992963 scopus 로고
    • Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen
    • Okamoto H, Tsuda F, Akahane Y etal. Hepatitis B virus with mutations in the core promoter for an e antigen-negative phenotype in carriers with antibody to e antigen. J. Virol. 1994; 68: 8102-10.
    • (1994) J. Virol. , vol.68 , pp. 8102-8110
    • Okamoto, H.1    Tsuda, F.2    Akahane, Y.3
  • 21
    • 0029817029 scopus 로고    scopus 로고
    • Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication
    • Buckwold VE, Xu Z, Chen M etal. Effects of a naturally occurring mutation in the hepatitis B virus basal core promoter on precore gene expression and viral replication. J. Virol. 1996; 70: 5845-51.
    • (1996) J. Virol. , vol.70 , pp. 5845-5851
    • Buckwold, V.E.1    Xu, Z.2    Chen, M.3
  • 22
    • 30744468144 scopus 로고    scopus 로고
    • Clinical significance of hepatitis B virus (HBV) genotypes and precore and core promoter mutations affecting HBV e antigen expression in Taiwan
    • Chen CH, Lee CM, Lu SN etal. Clinical significance of hepatitis B virus (HBV) genotypes and precore and core promoter mutations affecting HBV e antigen expression in Taiwan. J. Clin. Microbiol. 2005; 43: 6000-6.
    • (2005) J. Clin. Microbiol. , vol.43 , pp. 6000-6006
    • Chen, C.H.1    Lee, C.M.2    Lu, S.N.3
  • 23
    • 34447309567 scopus 로고    scopus 로고
    • Clinical significance and evolution of core promoter and precore mutations in HBeAg-positive patients with HBV genotype B and C: a longitudinal study
    • Chen CH, Lee CM, Hung CH etal. Clinical significance and evolution of core promoter and precore mutations in HBeAg-positive patients with HBV genotype B and C: a longitudinal study. Liver Int. 2007; 27: 806-15.
    • (2007) Liver Int. , vol.27 , pp. 806-815
    • Chen, C.H.1    Lee, C.M.2    Hung, C.H.3
  • 24
    • 0028888409 scopus 로고
    • Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance
    • Lok AS, Akarca US, Greene S. Predictive value of precore hepatitis B virus mutations in spontaneous and interferon-induced hepatitis B e antigen clearance. Hepatology 1995; 21: 19-24.
    • (1995) Hepatology , vol.21 , pp. 19-24
    • Lok, A.S.1    Akarca, U.S.2    Greene, S.3
  • 25
    • 0042388207 scopus 로고    scopus 로고
    • Low HBeAg serum levels correlate with the presence of the double A1762T/G1764A core promoter mutation and a positive response to interferon in patients with chronic hepatitis B virus infection
    • Marrone A, Zampino R, Luongo G, Utili R, Karayiannis P, Ruggiero G. Low HBeAg serum levels correlate with the presence of the double A1762T/G1764A core promoter mutation and a positive response to interferon in patients with chronic hepatitis B virus infection. Intervirology 2003; 46: 222-6.
    • (2003) Intervirology , vol.46 , pp. 222-226
    • Marrone, A.1    Zampino, R.2    Luongo, G.3    Utili, R.4    Karayiannis, P.5    Ruggiero, G.6
  • 26
    • 0033998982 scopus 로고    scopus 로고
    • Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B
    • Erhardt A, Reineke U, Blondin D etal. Mutations of the core promoter and response to interferon treatment in chronic replicative hepatitis B. Hepatology 2000; 31: 716-25.
    • (2000) Hepatology , vol.31 , pp. 716-725
    • Erhardt, A.1    Reineke, U.2    Blondin, D.3
  • 27
    • 0033045135 scopus 로고    scopus 로고
    • Hepatitis B virus genotype assignment using restriction fragment length polymorphism patterns
    • Mizokami M, Nakano T, Orito E etal. Hepatitis B virus genotype assignment using restriction fragment length polymorphism patterns. FEBS Lett. 1999; 450: 66-71.
    • (1999) FEBS Lett. , vol.450 , pp. 66-71
    • Mizokami, M.1    Nakano, T.2    Orito, E.3
  • 28
    • 70349240414 scopus 로고    scopus 로고
    • Chronic hepatitis B: update 2009
    • Lok ASF, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology 2009; 50: 1-36.
    • (2009) Hepatology , vol.50 , pp. 1-36
    • Lok, A.S.F.1    McMahon, B.J.2
  • 29
    • 51049107683 scopus 로고    scopus 로고
    • Asian-pacific consensus statement on the management of chronic hepatitis B: a 2008 update
    • Liaw YF, Leung N, Kao JH etal. Asian-pacific consensus statement on the management of chronic hepatitis B: a 2008 update. Hepatol. Int. 2008; 2: 263-83.
    • (2008) Hepatol. Int. , vol.2 , pp. 263-283
    • Liaw, Y.F.1    Leung, N.2    Kao, J.H.3
  • 30
    • 0038045171 scopus 로고    scopus 로고
    • Peginterferon alpha-2a (40 kDa): an advance in the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Cooksley WG, Piratvisuth T, Lee SD etal. Peginterferon alpha-2a (40 kDa): an advance in the treatment of hepatitis B e antigen-positive chronic hepatitis B. J. Viral. Hepat. 2003; 10: 298-305.
    • (2003) J. Viral. Hepat. , vol.10 , pp. 298-305
    • Cooksley, W.G.1    Piratvisuth, T.2    Lee, S.D.3
  • 31
    • 0033816667 scopus 로고    scopus 로고
    • Interferon-alpha therapy in chronic hepatitis B: early monitoring of hepatitis B e antigen may help to decide whether to stop or to prolong therapy
    • Heijtink RA, Janssen HL, Hop WC etal. Interferon-alpha therapy in chronic hepatitis B: early monitoring of hepatitis B e antigen may help to decide whether to stop or to prolong therapy. J. Viral. Hepat. 2000; 7: 382-6.
    • (2000) J. Viral. Hepat. , vol.7 , pp. 382-386
    • Heijtink, R.A.1    Janssen, H.L.2    Hop, W.C.3
  • 32
    • 0029806124 scopus 로고    scopus 로고
    • Use of quantitative assays for hepatitis B e antigen and IgM antibody to hepatitis B core antigen to monitor therapy in chronic hepatitis B
    • Hayashi PH, Beames MP, Kuhns MC, Hoofnagle JH, Di Bisceglie AM. Use of quantitative assays for hepatitis B e antigen and IgM antibody to hepatitis B core antigen to monitor therapy in chronic hepatitis B. Am. J. Gastroenterol. 1996; 91: 2323-8.
    • (1996) Am. J. Gastroenterol. , vol.91 , pp. 2323-2328
    • Hayashi, P.H.1    Beames, M.P.2    Kuhns, M.C.3    Hoofnagle, J.H.4    Di Bisceglie, A.M.5
  • 33
    • 39549114267 scopus 로고    scopus 로고
    • HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B
    • Fried MW, Piratvisuth T, Lau GK etal. HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a for HBeAg-positive chronic hepatitis B. Hepatology 2008; 47: 428-34.
    • (2008) Hepatology , vol.47 , pp. 428-434
    • Fried, M.W.1    Piratvisuth, T.2    Lau, G.K.3
  • 34
    • 77953282645 scopus 로고    scopus 로고
    • Comparison between quantitative hepatitis B surface antigen, hepatitis B e-antigen and hepatitis B virus DNA levels for predicting virological response to pegylated interferon-a-2b therapy in hepatitis B e-antigen-positive chronic hepatitis B
    • Tangkijvanich P, Komolmit P, Mahachai V, Sa-Nguanmoo P, Theamboonlers A, Poovorawan Y. Comparison between quantitative hepatitis B surface antigen, hepatitis B e-antigen and hepatitis B virus DNA levels for predicting virological response to pegylated interferon-a-2b therapy in hepatitis B e-antigen-positive chronic hepatitis B. Hepatol. Res. 2010; 40: 269-77.
    • (2010) Hepatol. Res. , vol.40 , pp. 269-277
    • Tangkijvanich, P.1    Komolmit, P.2    Mahachai, V.3    Sa-Nguanmoo, P.4    Theamboonlers, A.5    Poovorawan, Y.6
  • 35
    • 84911806946 scopus 로고    scopus 로고
    • Changes in serum hepatitis B e antigen (HBeAg) levels associated with the emergence of YMDD mutants in HBeAg non-seroconverted patients during lamivudine therapy
    • Yen YH, Lu SN, Chen CH etal. Changes in serum hepatitis B e antigen (HBeAg) levels associated with the emergence of YMDD mutants in HBeAg non-seroconverted patients during lamivudine therapy. Liver Int. 2007; 34: 1034-55.
    • (2007) Liver Int. , vol.34 , pp. 1034-1055
    • Yen, Y.H.1    Lu, S.N.2    Chen, C.H.3
  • 36
    • 28844435348 scopus 로고    scopus 로고
    • Comparison of sequence changes of precore and core promoter regions in HBeAg-positive chronic hepatitis B patients with and without HBeAg clearance in lamivudine therapy
    • Chen CH, Lee CM, Lu SN etal. Comparison of sequence changes of precore and core promoter regions in HBeAg-positive chronic hepatitis B patients with and without HBeAg clearance in lamivudine therapy. J. Hepatol. 2006; 44: 76-82.
    • (2006) J. Hepatol. , vol.44 , pp. 76-82
    • Chen, C.H.1    Lee, C.M.2    Lu, S.N.3
  • 37
    • 0027142488 scopus 로고
    • Long-term follow-up of chronic hepatitis B patients treated with interferon alfa
    • Lok AS, Chung HT, Liu VW, Ma OC. Long-term follow-up of chronic hepatitis B patients treated with interferon alfa. Gastroenterology 1993; 105: 1833-8.
    • (1993) Gastroenterology , vol.105 , pp. 1833-1838
    • Lok, A.S.1    Chung, H.T.2    Liu, V.W.3    Ma, O.C.4
  • 38
    • 0033027690 scopus 로고    scopus 로고
    • Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection
    • Lin SM, Sheen IS, Chien RN, Chu CM, Liaw YF. Long-term beneficial effect of interferon therapy in patients with chronic hepatitis B virus infection. Hepatology 1999; 29: 971-5.
    • (1999) Hepatology , vol.29 , pp. 971-975
    • Lin, S.M.1    Sheen, I.S.2    Chien, R.N.3    Chu, C.M.4    Liaw, Y.F.5
  • 39
    • 0030730879 scopus 로고    scopus 로고
    • Long-term follow-up of patients with chronic hepatitis B treated with interferon alfa
    • Lau DT, Everhart J, Kleiner DE etal. Long-term follow-up of patients with chronic hepatitis B treated with interferon alfa. Gastroenterology 1997; 113: 1660-7.
    • (1997) Gastroenterology , vol.113 , pp. 1660-1667
    • Lau, D.T.1    Everhart, J.2    Kleiner, D.E.3
  • 40
    • 48549107919 scopus 로고    scopus 로고
    • Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg-positive patients treated with peginterferon alpha-2b
    • Buster EH, Flink HJ, Cakaloglu Y etal. Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg-positive patients treated with peginterferon alpha-2b. Gastroenterology 2008; 135: 459-67.
    • (2008) Gastroenterology , vol.135 , pp. 459-467
    • Buster, E.H.1    Flink, H.J.2    Cakaloglu, Y.3
  • 41
    • 51049088452 scopus 로고    scopus 로고
    • Sustained response to peginterferon alfa-2a (40 kDa) with or without lamivudine in Asian patients with HBeAg-positive and HBeAg-negative chronic hepatitis B
    • Piratvisuth T, Lau G, Chao YC etal. Sustained response to peginterferon alfa-2a (40 kDa) with or without lamivudine in Asian patients with HBeAg-positive and HBeAg-negative chronic hepatitis B. Hepatol. Int. 2008; 2: 102-10.
    • (2008) Hepatol. Int. , vol.2 , pp. 102-110
    • Piratvisuth, T.1    Lau, G.2    Chao, Y.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.