Thrombopoietin to replace megakaryocyte-derived growth factor: Impact on stem and progenitor cells during ex vivo expansion of CD34+ cells mobilized in peripheral blood

Transfusion

Volumn 51, Issue 2, 2011, Pages 313-318

  Duchez, Pascale ^a   Chevaleyre, Jean ^a   Vlaski, Marija ^a   Dazey, Bernard ^a   Bijou, Fontanet ^a   Lafarge, Xavier ^a   Milpied, Noãl ^a   Boiron, Jean Michel ^a   Ivanovic, Zoran ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD33 ANTIGEN; CD34 ANTIGEN; CD61 ANTIGEN; FIBRINOGEN RECEPTOR; GRANULOCYTE COLONY STIMULATING FACTOR; MEGAKARYOCYTE GROWTH AND DEVELOPMENT FACTOR; MICROSOMAL AMINOPEPTIDASE; STEM CELL FACTOR; THROMBOPOIETIN;

ARTICLE; BLOOD SUBSTITUTION; CONTROLLED STUDY; ENGRAFTMENT; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; MAJOR CLINICAL STUDY; MEGAKARYOCYTE; MYELOMA; NEUTROPENIA; PHENOTYPE; STEM CELL EXPANSION; STEM CELL MOBILIZATION;

ANIMALS; ANTIGENS, CD34; CELL DIVISION; CELLS, CULTURED; CULTURE MEDIA, SERUM-FREE; GRAFT SURVIVAL; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HEMATOPOIETIC STEM CELLS; HUMANS; IMMUNOPHENOTYPING; MICE; MICE, INBRED NOD; MICE, SCID; MULTIPLE MYELOMA; POLYETHYLENE GLYCOLS; STEM CELL FACTOR; THROMBOPOIETIN; TRANSPLANTATION, HETEROLOGOUS;

EID: 79951651573     PISSN: 00411132     EISSN: 15372995     Source Type: Journal    
DOI: 10.1111/j.1537-2995.2010.02860.x     Document Type: Article

References (21)

1. Reiffers J, Cailliot C, Dazey B, Attal M, Caraux J, Boiron JM,. Abrogation of post-myeloablative chemotherapy neutropenia by ex-vivo expanded autologous CD34-positive cells. Lancet 1999; 354: 1092-3. (Pubitemid 29452824)
2. Boiron J-M, Dazey B, Caillot C, Launay B, Attal M, Mazurier F, McNiece IK, Ivanovic Z, Caraux J, Marit G, Reiffers J,. The ex vivo expansion of CD34+ cells allows prediction of neutropenia abrogation after autologous transplantation without impairing the long term engraftment capacity. Transfusion 2006; 46: 1934-42. (Pubitemid 44631601)
3. Ivanovic Z, Duchez P, Dazey B, Hermitte F, Lamrissi-Garcia I, Mazurier F, Praloran V, Reiffers J, Vezon G, Boiron JM,. A clinical-scale expansion of mobilized CD34+ hematopoietic stem and progenitor cells by using a new serum-free medium. Transfusion 2006; 46: 126-31. (Pubitemid 43381795)
4. Hunt P, Li YS, Nichol JL, Hokom MM, Bogenberger JM, Swift SE, Skrine JD, Hornkohl AC, Lu H, Clogston C, Merewether LA, Johnson MJ, Parker V, Knudten A, Farese A, Hsu RY, Garcia A, Stead R, Bosselman RA, Bartley TD,. Purification and biologic characterization of plasma-derived megakaryocyte growth and development factor. Blood 1995; 86: 540-7.
5. Debili N, Wendling F, Katz A, Guichard J, Breton-Gorius J, Hunt P, Vainchenker W,. The Mpl-ligand or thrombopoietin or megakaryocyte growth and differentiative factor has both direct proliferative and differentiative activities on human megakaryocyte progenitors. Blood 1995; 86: 2516-25.
6. Abraham R, Basser RL,. Megakaryocyte growth and development factor: a review of early clinical studies. Oncologist 1997; 2: 311-8. (Pubitemid 27456317)
7. Jeanne M, Bouzgarrou R, Lafarge X, Fizet D, Dazey B, Vezon G, Ivanovic Z,. Comparison of CD34+ cell collection on the CS-3000+ and Amicus blood cell separators. Transfusion 2003; 43: 1423-7. (Pubitemid 37322503)
8. Ivanovic Z, Hermitte F, Brunet de la Grange P, Dazey B, Belloc F, Lacombe F, Vezon G, Praloran V,. Simultaneous maintenance of human cord blood SCID-repopulating cells and expansion of committed progenitors at low O2 concentration (3%). Stem Cells 2004; 22: 716-24. (Pubitemid 39166929)
9. Levac K, Karanu F, Bhatia M,. Identification of growth factor conditions that reduce ex vivo cord blood progenitor cell expansion but do not alter human repopulating cell function in vivo. Heamatologica 2005; 90: 166-72. (Pubitemid 40293276)
10. Ivanovic Z, Boiron JM,. Ex vivo expansion of hematopoietic stem cells: concept and clinical benefit. Transfus Clin Biol 2009; 16: 489-500.
11. Milpied NJ, Marit G, Dazey B, Boiron JM, Ivanovic Z, Foucaud C, Bijou F, Bouabdallah K, Schmitt A, Sauvezie M, Cailliot C, Reiffers J,. Ex vivo Expanded peripheral Blood stem Cells (EVEC) Compared with Un Manipulated Peripheral Blood Stem Cells (PBSC). Autologous Transplantation for Multiple Myeloma: a pair match analysis. 2009;114: 207. ASH Annual Meeting Abstracts, 51th ASH annual Meeting. New Orleans. December 2009.
12. Tura O, Barclay GR, Roddie H, Davies J, Turner ML,. Optimal ex vivo expansion of henutrophils from PBSC CD34+ cells by a combination of SCF, Flt3-L and G-CSF and its inhibition by further addition of TPO. J Transl Med 2007; 5: 1-11.
13. Huang H, Cantor AB,. Common features of megakaryocytes and hematopoietic stem cells: what's the connection? J Cell Biochem 2009; 107: 857-64.
14. Yoshida K, Kirito K, Yongzhen H, Ozawa K, Kaushansky K, Komatsu N,. Thrombopoietin (TPO) regulates HIF-1alpha levels through generation of mitochondrial reactive oxygen species. Int J Hematol 2008; 88: 43-51.
15. Yoshihara H, Arai F, Hosokawa K, Hagiwara T, Takubo K, Nakamura Y, Gomei Y, Iwasaki H, Matsuoka S, Miyamoto K, Miyazaki H, Takahashi T, Suda T,. Thrombopoietin/MPL signaling regulates hematopoietic stem cell quiescence and interaction with the osteoblastic niche. Cell Stem Cell 2007; 1: 685-97. (Pubitemid 350215333)
16. Arai F, Yoshihara H, Hosokawa K, Nakamura Y, Gomei Y, Iwasaki H, Suda T,. Niche regulation of hematopoietic stem cells in the endosteum. Ann N Y Acad Sci 2009; 1176: 36-46.
17. IvanoviÄ Z, Bartolozzi B, Bernabei PA, Cipolleschi MG, Rovida E, MilenkoviÄ P, Praloran V, Dello Sbarba P,. Incubation of murine bone marrow cells in hypoxia ensures the maintenance of marrow-repopulating ability together with the expansion of committed progenitors. Br J Haematol 2000; 108: 424-9. (Pubitemid 30143662)
18. IvanoviÄ Z, Dello Sbarba P, Trimoreau F, Faucher JL, Praloran V,. Primitive human HPCs are better maintained and expanded in vitro at 1 percent oxygen than at 20 percent. Transfusion 2000; 40: 1482-8. (Pubitemid 32049053)
19. Danet GH, Pan Y, Luongo JL, Bonnet DA, Simon MC,. Expansion of human SCID-repopulating cells under hypoxic conditions. J Clin Invest 2003; 112: 126-35. (Pubitemid 38056384)
20. Mostafa SS, Miller WM, Papoutsakis ET,. Oxygen tension influences the differentiation, maturation and apoptosis of human megakaryocytes. Br J Haematol 2000; 111: 879-89. (Pubitemid 32098927)
21. Ivanovic Z,. Hypoxia or in situ normoxia: the stem cell paradigm. J Cell Physiol 2009; 219: 271-7.