Molecular Biology-Based Assessment of Vitamin E-Coated Dialyzer Effects on Oxidative Stress, Inflammation, and Vascular Remodeling

Artificial Organs

Volumn 35, Issue 2, 2011, Pages

  Calò, Lorenzo A ^a   Naso, Agostino ^b   D'Angelo, Angela ^b   Pagnin, Elisa ^a   Zanardo, Marco ^a   Puato, Massimo ^a   Rebeschini, Mirka ^b   Landini, Silvano ^c   Feriani, Mariano ^c   Perego, Angelo ^d   Malagoli, Andrea ^d   Zagatti, Riccardo ^a   Calzavara, Piergianni ^a   Cascone, Carmelo ^a   Davis, Paul A ^e  

^a Department of Clinical and Experimental Medicine ^*

^b UNIVERSITY HOSPITAL OF PADOVA   (Italy)

^c General Hospital of Mestre   (Italy)

^d Hospital of Monselice   (Italy)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Cardiovascular remodeling; Hemodialysis; Inflammation; Oxidative stress

Indexed keywords

CARDIOLOGY; DISEASES; ELECTROPHORESIS; ENZYME ACTIVITY; MOLECULAR BIOLOGY; OXIDATIVE STRESS; PATHOLOGY;

CARDIOVASCULAR DISEASE; CARDIOVASCULAR REMODELING; CAROTID INTIMA-MEDIA THICKNESS; END-STAGE RENAL DISEASE PATIENTS; HAEMODIALYSIS; HEME OXYGENASE-1; OXIDIZED LOW-DENSITY LIPOPROTEINS; PLASMINOGEN ACTIVATOR INHIBITOR-1; VASCULAR REMODELING; VITAMIN-E;

DIALYSIS;

ALPHA 2 GLOBULIN; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA TOCOPHEROL; ANTIOXIDANT; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CALCIUM; CALCIUM CARBONATE; CALCIUM CHANNEL BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROPOIETIN; FOLIC ACID; HEME OXYGENASE 1; HEMOGLOBIN; LANTHANUM CARBONATE; OXIDIZED LOW DENSITY LIPOPROTEIN; P22 PHOX; PHOSPHATE BINDING AGENT; PHOSPHORYLATED EXTRACELLULAR SIGNAL REGULATED KINASE 1; PHOSPHORYLATED EXTRACELLULAR SIGNAL REGULATED KINASE 2; PLASMINOGEN ACTIVATOR INHIBITOR 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SEVELAMER; SUPEROXIDE; UNCLASSIFIED DRUG; VITAMIN D;

ADULT; ANGIOGENESIS; ANTIOXIDANT ACTIVITY; ARTICLE; ARTIFICIAL KIDNEY; ATHEROGENESIS; BIOCOMPATIBILITY; BLOOD LEVEL; BLOOD VESSEL DIAMETER; CAROTID ARTERY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HEMODIALYSIS; HUMAN; HYPERTENSION; INFLAMMATION; INTIMA MEDIA THICKNESS; KIDNEY FAILURE; LYMPHOCYTE; MALE; MOLECULAR BIOLOGY; MONOCYTE; MONONUCLEAR CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; VASCULAR REMODELING; VITAMIN E COATED POLYSULFONE MEMBRANE; WESTERN BLOTTING;

EID: 79951634059     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2010.01125.x     Document Type: Article

References (36)

1. Luke RG. Chronic renal failure-a vasculopathic state. N Engl J Med 1998;339:841-3.
2. Locatelli F, Canaud B, Eckardt K, Stenvinkel P, Wanner C, Zoccali C. Oxidative stress in end-stage renal disease: an emerging threat to patient outcome. Nephrol Dial Transplant 2003;18:1272-80.
3. Massy ZA, Stenvinkel P, Drueke TB. The role of oxidative stress in chronic kidney disease. Semin Dial 2009;22:405-8.
4. Stenvinkel P, Heinburger O, Paultre F, etal. Strong associations between malnutrition, inflammation and atherosclerosis in chronic renal failure. Kidney Int 1999;55:1899-911.
5. Zimmermann J, Herrlinger S, Pruy A, Metzger T, Wanner C. Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int 1999;55:648-58.
6. Foley RN. Clinical epidemiology of cardiac disease in dialysis patients: left ventricular hypertrophy, ischemic heart disease, and cardiac failure. Semin Dial 2003;16:111-7.
7. Calò LA, Naso A, Pagnin E, etal. Vitamin E-coated dialyzers reduce oxidative stress related proteins and markers in hemodialysis-a molecular biological approach. Clin Nephrol 2004;62:355-61.
8. Westhuyzen J, Saltissi D, Stanbury V. Oxidative stress and erythrocyte integrity in end-stage renal failure patients hemodialysed using a vitamin E-modified membrane. Ann Clin Lab Sci 2003;33:3-10.
9. Sommerburg O, Sostmann K, Grune T, Ehrich JHH. Oxidative stress in hemodialysis patients treated with a dialysis membrane which has alpha-tocopherol bonded to its surface. Biofactors 1999;10:121-4.
10. Pertosa G, Grandaliano G, Soccio M, Martino C, Gesualdo L, Schena FP. Vitamin E-modified filters modulate Jun N-terminal kinase activation in peripheral blood mononuclear cells. Kidney Int 2002;62:602-10.
11. Griendling KK, Soresen D, Ushio-Fukai M. NAD(P)H oxidase. Role in cardiovascular biology and disease. Circ Res 2000;86:494-501.
12. Babior BM. NADPH oxidase: an update. Blood 1999;93:1464-76.
13. Dimova EY, Samoylenko A, Kietzmann T. Oxidative stress and hypoxia: implications for plasminogen activator inhibitor-1 expression. Antioxid Redox Signal 2004;6:777-91.
14. Maines MD. The heme oxygenase system: a regulator of second messenger gases. Annu Rev Pharmacol Toxicol 1997;37:517-54.
15. McCubrey JA, Lahair MM, Franklin RA. Reactive oxygen species-induced activation of the MAP kinase signaling pathways. Antioxid Redox Signal 2006;8:1775-89.
16. Harrison D, Griendling KK, Landmesser U, Hornig B, Drexler H. Role of oxidative stress in atherosclerosis. Am J Cardiol 2003;91:7-11.
17. Calò LA, Naso A, Carraro G, etal. Effect of haemodiafiltration with online regeneration of ultrafiltrate on oxidative stress in dialysis patients. Nephrol Dial Transplant 2007;22:1413-9.
18. Calò LA, Naso A, Davis PA, etal. Hemodiafiltration with on-line regeneration of ultrafiltrate: effect on HO-1 and iNOS and implication for oxidative stress and inflammation. Artif Organs 2011;35:183-7.
19. Calò LA, Pagnin E, Ceolotto G, etal. Silencing regulator of G protein signaling-2 (RGS-2) increases angiotensin II signaling: insights into hypertension from findings in Bartter's/Gitelman's syndromes. J Hypertens 2008;26:938-45.
20. Calò LA, Schiavo S, Davis PA, etal. Angiotensin II signaling via type 2 receptors in a human model of vascular hyporeactivity: implications for hypertension. J Hypertens 2010;28:111-8.
21. Touboul PJ, Hennerici MG, Meairs S, etal. Mannheim intima-media thickness consensus. Cerebrovasc Dis 2004;18:346-9.
22. Pauletto P, Palatini P, Da Ros S, etal. Factors underlying the increase in carotid intima-media thickness in borderline hypertensives. Arterioscler Thromb Vasc Biol 1999;19:1231-7.
23. Filiopoulos V, Hadjiyannakos D, Metaxaki P, etal. Inflammation and oxidative stress in patients on hemodiafiltration. Am J Nephrol 2008;28:949-57.
24. Walker RJ, Sutherland WH, De Jong SA. Effect of changing from a cellulose acetate to a polysulfone dialysis membrane on protein oxidation and inflammation markers. Clin Nephrol 2004;61:198-206.
25. Sasaki M. Development of vitamin E-modified polysulfone membrane dialyzers. J Artif Organs 2006;9:50-60.
26. Dhalla NS, Temsha RM, Netticadan T. Role of oxidative stress in cardiovascular diseases. J Hypertens 2000;18:655-73.
27. Takeda K, Ichiki T, Tokunou T, etal. Critical role of Rho-kinase and MEK-ERK pathways for angiotensin II-induced plasminogen activator inhibitor type-1 gene expression. Arterioscler Thromb Vasc Biol 2001;21:868-73.
28. Vaughan DE. PAI-1 and atherothrombosis. J Thromb Haemost 2005;3:1879-83.
29. Dichtl W, Stiko A, Eriksson P, etal. Oxidized LDL and lysophosphatidylcholine stimulate plasminogen activator inhibitor-1 expression in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 1999;19:3025-32.
30. Meisinger C, Baumert J, Khuseyinova N, Loewel H, Koenig W. Plasma oxidized low-density lipoprotein, a strong predictor for acute coronary heart disease events in apparently healthy, middle aged men from the general population. Circulation 2005;112:651-7.
31. Stocker R, Yamamoto Y, McDonagh AF, Glazer AN, Ames BN. Bilirubin is an antioxidant of possible physiological importance. Science 1987;235:1043-6.
32. Immenschuh S, Ramadori G. Gene regulation of heme oxygenase-1 as a therapeutic target. Biochem Pharmacol 2000;60:1121-8.
33. Kim S, Iwao H. Molecular and cellular mechanisms of Ang II-mediated cardiovascular and renal diseases. Pharmacol Rev 2000;52:11-34.
34. Benedetto FA, Mallamaci F, Tripepi G, Zoccali C. Prognostic value of ultrasonographic measurement of carotid intima media thickness in dialysis patients. J Am Soc Nephrol 2001;12:2458-64.
35. Kato A, Takita T, Maruyama Y, Kumagai H, Hishida A. Impact of carotid atherosclerosis on long-term mortality in chronic hemodialysis patients. Kidney Int 2003;64:1472-9.
36. Ekart R, Hojs R, Hojs-Fabjan T, Balon BP. Predictive value of carotid intima media thickness in hemodialysis patients. Artif Organs 2005;29:615-9.