Luteolin suppresses growth and migration of human lung cancer cells

Molecular Biology Reports

Volumn 38, Issue 2, 2011, Pages 1115-1119

  Zhao, Yunxue ^a   Yang, Guotao ^b   Ren, Dongmei ^a   Zhang, Xiumei ^a   Yin, Qiuwei ^b   Sun, Xuefei ^b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Apoptosis; Cell cycle; Lung cancer; Luteolin; Migration; Stress fiber

Indexed keywords

LUTEOLIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL MIGRATION; CELL STRAIN; CELL STRAIN A549; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; LUNG CANCER; STRESS FIBER;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL MOVEMENT; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LUNG NEOPLASMS; LUTEOLIN; MEMBRANE POTENTIALS; MICE; MITOCHONDRIAL MEMBRANES;

EID: 79951581481     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-0208-x     Document Type: Article

References (24)

1. Y Lin R Shi X Wang HM Shen 2008 Luteolin, a flavonoid with potential for cancer prevention and therapy Curr Cancer Drug Targets 8 634 646 1:CAS:528:DC%2BD1cXhtlCgs7zJ 10.2174/156800908786241050 18991571
2. M López-Lázaro 2009 Distribution and biological activities of the flavonoid luteolin Mini Rev Med Chem 9 31 59 10.2174/138955709787001712 19149659
3. DM Ren Z Qu XN Wang, et al. 2008 Simultaneous determination of nine major active compounds in Dracocephalum rupestre by HPLC J Pharm Biomed Anal 48 1441 1445 1:CAS:528:DC%2BD1MXntlygtA%3D%3D 10.1016/j.jpba.2008.09.013 18930620
4. Y Zhou Y Zhao KM O'Boyle PV Murphy 2008 Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis Bioorg Med Chem Lett 18 954 957 1:CAS:528:DC%2BD1cXhsFWktL8%3D 10.1016/j.bmcl.2007.12.034 18166456 (Pubitemid 351193004)
5. Y Zhao Y Zhou KM O'Boyle PV Murphy 2008 Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis Bioorg Med Chem 16 6333 6337 1:CAS:528:DC%2BD1cXntlagtrk%3D 10.1016/j.bmc.2008.05.012 18504133 (Pubitemid 351783422)
6. Z Wang X Tang Y Li C Leu L Guo X Zheng D Zhu 2008 20- Hydroxyeicosatetraenoic acid inhibits the apoptotic responses in pulmonary artery smooth muscle cells Eur J Pharmacol 588 1 9 17 1:CAS:528: DC%2BD1cXmsFKlu78%3D 10.1016/j.ejphar.2008.03.045 18455723
7. Y Zhao J Li Y Xing J Wang C Lu X Xin M Geng 2008 N- acetylglucosaminyltransferase V mediates cell migration and invasion of mouse mammary tumor cells 4TO7 via RhoA and Rac1 signaling pathway Mol Cell Biochem 309 109 208 10.1007/s11010-007-9656-6
8. Hong L, Sun H, Lv X, Yang D, Zhang J, Shi Y (2009) Expression of periostin in the serum of NSCLC and its function on proliferation and migration of human lung adenocarcinoma cell line (A549) in vitro. Mol Biol Rep. doi: 10.1007/s11033-009-9721-1
9. P Zhang W Liu J Zhang H Guan W Chen X Cui Q Liu A Jiang 2010 Gene expression profiles in the PC-3 human prostate cancer cells induced by NKX3.1 Mol Biol Rep 37 3 1505 1512 1:CAS:528:DC%2BC3cXhtlajsLY%3D 10.1007/s11033-009- 9549-8 19462257
10. Jiang GX, Zhong XY, Cui YF, Liu W, Tai S, Wang ZD, Shi YG, Zhao SY, Li CL (2010) IL-6/STAT3/TFF3 signaling regulates human biliary epithelial cell migration and wound healing in vitro. Mol Biol Rep. doi: 10.1007/s11033-010- 0036-z
11. Zhang L, Huang H, Wu K, Wang M, Wu B (2009) Impact of BTG2 expression on proliferation and invasion of gastric cancer cells in vitro. Mol Biol Rep. doi: 10.1007/s11033-009-9777-y
12. F Casagrande JM Darbon 2001 Effects of structurally related flavonoids on cell cycle progression of human melanoma cells: regulation of cyclin-dependent kinases CDK2 and CDK1 Biochem Pharmacol 61 1205 1215 1:CAS:528: DC%2BD3MXivFegtb4%3D 10.1016/S0006-2952(01)00583-4 11322924 (Pubitemid 32375112)
13. HW Leung CH Wu CH Lin HZ Lee 2005 Luteolin induced DNA damage leading to human lung squamous carcinoma CH27 cell apoptosis Eur J Pharmacol 508 77 83 1:CAS:528:DC%2BD2MXmvFyqtQ%3D%3D 10.1016/j.ejphar.2004.12.032 15680256 (Pubitemid 40169904)
14. B Wu Q Zhang W Shen J Zhu 2008 Anti-proliferative and chemosensitizing effects of luteolin on human gastric cancer AGS cell line Mol Cell Biochem 313 125 132 1:CAS:528:DC%2BD1cXmtlSru74%3D 10.1007/s11010-008-9749-x 18398671
15. Q Zhang XH Zhao ZJ Wang 2008 Flavones and flavonols exert cytotoxic effects on a human oesophageal adenocarcinoma cell line (OE33) by causing G2/M arrest and inducing apoptosis Food Chem Toxicol 46 2042 2053 1:CAS:528:DC%2BD1cXlvVShs78%3D 10.1016/j.fct.2008.01.049 18331776
16. JF Tait 2008 Imaging of apoptosis J Nucl Med 49 1573 1576 10.2967/jnumed.108.052803 18794267
17. KW Hunter NP Crawford J Alsarraj 2008 Mechanisms of metastasis Breast Cancer Res 10 Suppl 1 S2 10.1186/bcr1988 19091006
18. Guo F, Liu Y, Li Y, Li G (2010) Inhibition of ADP-ribosylation factor-like 6 interacting protein 1 suppresses proliferation and reduces tumor cell invasion in CaSki human cervical cancer cells. Mol Biol Rep. doi: 10.1007/s11033-010-0037-y
19. Lee JS, Kim IS (2009) Leukotactin-1/CCL15 induces cell migration and differentiation of human eosinophilic leukemia EoL-1 cells through PKCdelta activation. Mol Biol Rep. doi: 10.1007/s11033-009-9687-z
20. D Palm K Lang B Brandt KS Zaenker F Entschladen 2005 In vitro and in vivo imaging of cell migration: two interdepending methods to unravel metastasis formation Semin Cancer Biol 15 396 404 10.1016/j.semcancer.2005.06.008 16054391 (Pubitemid 41140307)
21. D Vignjevic G Montagnac 2008 Reorganisation of the dendritic actin network during cancer cell migration and invasion Semin Cancer Biol 18 12 22 1:CAS:528:DC%2BD2sXhsVOks7fN 10.1016/j.semcancer.2007.08.001 17928234 (Pubitemid 350266367)
22. K Ren H Jin C Bian H He X Liu S Zhang Y Wang RG Shao 2008 MR-1 modulates proliferation and migration of human hepatoma HepG2 cells through myosin light chains-2 (MLC2)/focal adhesion kinase (FAK)/Akt signaling pathway J Biol Chem 283 35598 35605 1:CAS:528:DC%2BD1cXhsVylsrvE 10.1074/jbc.M802253200 18948272
23. Wang SY, Wang K, Xin Y, Lv DC (2009) Maggot excretions/secretions induces human microvascular endothelial cell migration through AKT1. Mol Biol Rep. doi: 10.1007/s11033-009-9806-x
24. Shi L, Zhao M, Luo Q, Ma YM, Zhong JL, Yuan XH, Huang CZ (2009) Overexpression of PIP5KL1 suppresses cell proliferation and migration in human gastric cancer cells. Mol Biol Rep. doi: 10.1007/s11033-009-9701-5