Inhibitory effect of memantine, an NMDA-receptor antagonist, on electoporation-induced inward currents in pituitary GH3 cells

Biochemical and Biophysical Research Communications

Volumn 405, Issue 3, 2011, Pages 508-513

  Wu, Sheng Nan ^a   Huang, Hsien Ching ^a   Yeh, Chia Chen ^a   Yang, Wei Hsin ^a   Lo, Yi Ching ^b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Electroporation; Ion current; Memantine; Pituitary cells

Indexed keywords

GLIBENCLAMIDE; MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; POTASSIUM CHANNEL; VOLTAGE GATED CALCIUM CHANNEL;

ARTICLE; CELL STRAIN GH3; CONTROLLED STUDY; ELECTROPORATION; HYPERPOLARIZATION; HYPOPHYSIS CELL; HYPOPHYSIS TUMOR; IC 50; INWARD CURRENT; ION CURRENT; NEUROENDOCRINE SYSTEM; POTASSIUM CURRENT; PRIORITY JOURNAL;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; ELECTROPORATION; MEMANTINE; MEMBRANE POTENTIALS; PITUITARY GLAND; RATS; RECEPTORS, N-METHYL-D-ASPARTATE;

EID: 79951580249     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.01.066     Document Type: Article

References (32)

1. Cheek E.R., Fast V.G. Nonlinear changes of transmembrane potential during electrical shocks: role of membrane electroporation. Circ. Res. 2004, 94:208-214.
2. Draghia-Akli R., Fiorotto M.L. A new plasmid-mediated approach to supplement somatotropin production in pigs. J. Anim. Sci. 2004, 82:E264-E269.
3. Dib-Hajj S.D., Choi J.S., Macala L.J., Tyrrell L., Black J.A., Cummins T.R., Waxman S.G. Transfection of rat or mouse neurons by biolistics or electroporation. Nat. Prot. 2009, 4:1118-1126.
4. Oliveira N.A., Cecchi C.R., Higuti E., Oliveira J.E., Jensen T.G., Bartolin P., Peroni C.N. Long-term human growth hormone expression and partial phenotypic correlation by plasmid-based gene therapy in an animal model of isolated growth hormone deficiency. J. Gene Med. 2010, 12:580-585.
5. Bonvallet R., Christé G. Membrane responses to large hyperpolarization in trabecles and single cells of frog atrium. Gen. Physiol. Biophys. 1988, 7:433-447.
6. Akuzawa-Tateyama M., Tateyama M., Ochi R. Low K+-induced hyperpolarizations trigger transient depolarizations and action potentials in rabbit ventricular myocytes. J. Physiol. 1998, 513:775-786.
7. Dyachok O., Zhabyeyev P., McDonald T.F. Electroporation-induced inward current in voltage-clamped guinea pig ventricular myocytes. J. Membrane Biol. 2010, 238:69-80.
8. Mobius H.J. Pharmacologic rationale for memantine in chronic cerebral hypoperfusion, especially vascular dementia. Alzheimer Dis. Assoc. Disord. 1999, 13:S172-S178. Suppl 3.
9. Muller W.E., Mutschler E., Riederer P. Noncompetitive NMDA receptor antagonists with fast open-channel blocking kinetics and strong voltage-dependency as potential therapeutic agents for Alzheimer's dementia. Pharmacopychiatry 1995, 28:113-124.
10. de Carvalho M., Printo S.C.J., Evangelista T., Ohana B., Printo A. A randomized, placebo-controlled trial of memantine for functional disability in amyotrophic lateral sclerosis, Amytroph. Lateral Scler. 2010, 11:456-460.
11. Lipton S.A. Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nat. Rev. Drug Discov. 2006, 5:160-170.
12. Netzer R., Bigalke H. Memantine reduces repetitive action potential firing in spinal cord nerve cell cultures. Eur. J. Pharmacol. 1990, 186:149-155.
13. Rammes G., Rupprecht R., Ferrari U., Zieglgansberger W., Parsons C.G. The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexane antagonize 5-HT3 receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner. Neurosci. Lett. 2001, 306:81-84.
14. Aracava Y., Pereira E.F., Maelicke A., Albuquerque E.X. Memantine blocks α7 nicotinic acetylcholine receptors more potently than N-methyl-D-aspartate receptors in rat hippocampal neurons. J. Pharmacol. Exp. Ther. 2005, 312:1195-1205.
15. Giustizieri M., Cucchiaroni M.L., Guatteo E., Bernardi G., Mercuri N.B., Berretta N. Memantine inhibits ATP-dependent K+ conductances in dopamine neurons of the rat substantia nigra pars compacta. J. Pharmacol. Exp. Ther. 2007, 322:721-729.
16. Komhuber J., Weller M., Schoppmeyer K., Riederer P. Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties. J. Neural Transm. Suppl. 1994, 43:91-104.
17. Wu S.N., Li H.F., Chiang H.T. Characterization of ATP-sensitive potassium channels functionally expressed in pituitary GH3 cells. J. Membrane Biol. 2000, 178:205-214.
18. Wu S.N., Jan C.R., Li H.F., Chiang H.T. Characterization of inhibition by risperidone of the inwardly rectifying K+ current in pituitary GH3 cells. Neuropsychopharmacology 2000, 23:676-689.
19. Huang M.H., Shen A.Y., Wang T.S., Wu H.M., Kang Y.F., Chen C.T., Hsu T.I., Chen B.S., Wu S.N. Inhibitory action of methadone and its metabolites on erg-mediated K+ current in GH3 pituitary tumor cells. Toxicology 2011, 280:1-9.
20. Wu S.N., Chang H.D. Diethyl pyrocarbonate, a histidine-modifying agent, directly stimulates activity of ATP-sensitive potassium channels in pituitary GH3 cells. Biochem. Pharmacol. 2006, 71:615-623.
21. Liu Y.C., Wang Y.J., Wu P.Y., Wu S.N. Tramadol-induced block of hyperpolarization-activated cation current in rat pituitary lactotrophs. Naunyn-Schmied. Arch. Pharmacol. 2009, 379:127-135.
22. Krassen H., Pliquett U., Neumann E. Nonlinear current-voltage relationship of the plasma membrane of single CHO cells. Bioelectrochemistry 2007, 70:71-77.
23. Jan C.R., Ho C.M., Wu S.N., Huang J.K., Tseng C.J. Mechanism of lanthanum inhibition of extracellular ATP-evoked calcium mobilization in MDCK cells. Life Sci 1998, 62:533-540.
24. Biagi B.A., Enyeart J.J. Gadolinium blocks low- and high-threshold calcium currents in pituitary cells. Am. J. Physiol. 1990, 259:C515-C520. (3 Pt 1).
25. Wu S.N., Li H.F., Jan C.R. Regulation of Ca2+-activated nonselective cationic currents in rat pituitary GH3 cells: involvement in L-type Ca2+ current. Brain Res. 1998, 812:133-141.
26. Wang M., Orwar O., Olofsson J., Weber S.G. Single-cell electoporation. Anal. Bioanal. Chem. 2010, 397:3235-3248.
27. Villalobos C., Garcia-Sancho J. Glutamate increases cytosolic calcium in GH3 pituitary cells acting via a high-affinity glutamate transporter. FASEB J. 1995, 9:815-819.
28. Lee M.C., Ting K.K., Adams S., Brew B.J., Chung R., Guillemin G.J. Characterization of the expression of NMDA receptors in human astrocytes. PLoS One 2010, 5:e14123.
29. Xia P., Chen H.S., Zhang D., Lipton S.A. Memantine preferentially blocks extrasynaptic over synaptic NMDA receptor currents in hippocampal autapses. J. Neurosci. 2010, 30:11246-11250.
30. Seeman P., Caruso C., Lasaga M. Memantine agonist action at dopamine D2high receptors. Synapse 2008, 62:149-153.
31. Liss B., Bruns R., Roeper J. Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons. EMBO J. 1999, 18:833-846.
32. Reichová N., Pazourek J., Polášková P., Havel J. Electrophoretic behavior of adamantane derivatives possessing antiviral activity and their determination by capillary zone electrophoresis with indirect detection. Electrophoresis 2002, 23:259-262.