Effect of NAT2 gene polymorphism on bladder cancer risk in Slovak population

Molecular Biology Reports

Volumn 38, Issue 2, 2011, Pages 1287-1293

  Klimčáková, Lucia ^a   Habalová, Viera ^a   Sivoňová, Monika ^b   Nagy, Vincent ^c   Šalagovič, Ján ^a   Židzik, Jozef ^a  

^a P J AFÁRIK UNIVERSITY   (Slovakia)

^b Faculty of Natural Sciences   (Slovakia)

^c L PASTEUR UNIVERSITY HOSPITAL   (Slovakia)

Author keywords

Bladder cancer; Cigarette smoking; NAT2; Polymorphism; Slovak population

Indexed keywords

ACETYLATION; AGE; AGED; ARTICLE; BLADDER CANCER; CANCER RISK; CANCER SUSCEPTIBILITY; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; FEMALE; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; N ACETYLTRANSFERASE 2 GENE; SEX DIFFERENCE; SLOVAKIA; SMOKING;

AMINES; ARYLAMINE N-ACETYLTRANSFERASE; ETHNIC GROUPS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK FACTORS; SEX FACTORS; SLOVAKIA; SMOKING; URINARY BLADDER NEOPLASMS;

EID: 79951578797     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-010-0228-6     Document Type: Article

References (36)

1. ECO/OEC European Cancer Observatory, Observatoire Européen du Cancer (2009) International Agency for Research on Cancer, Lyon. http://eu-cancer.iarc.fr
2. Silverman DT, Morrison AS, Devesa SS (1996) Bladder cancer. In: Schottenfeld D, Fraumeni JF Jr (eds) Cancer epidemiology and prevention. Oxford University Press, New York, pp 1156-1179
3. SS Hecht 1999 Tobacco smoke carcinogens and lung cancer J Natl Cancer Inst 91 1194 1210 1:CAS:528:DyaK1MXltVOhu7w%3D 10.1093/jnci/91.14.1194 10413421 (Pubitemid 29357186)
4. M Blum DM Grant W Mcbride M Heim UA Meyer 1990 Human arylamine N-acetyltransferase genes: isolation, chromosomal localization, and functional expression DNA Cell Biol 9 193 203 1:CAS:528:DyaK3cXls1Kns7w%3D 10.1089/dna.1990.9.193 2340091
5. I Cascorbi N Drakoulis J Brockmöller A Maurer K Sperling I Roots 1995 Arylamine N-acetyltransferase (NAT2) mutations and their allelic linkage in unrelated Caucasian individuals: correlation with phenotypic activity Am J Hum Genet 57 581 592 1:CAS:528:DyaK2MXotFemtrc%3D 7668286
6. RK Ross PA Jones MC Yu 1996 Bladder cancer epidemiology and pathogenesis Semin Oncol 23 536 545 1:STN:280:DyaK2s%2FkvFWgtA%3D%3D 8893866 (Pubitemid 26362215)
7. GM Lower Jr T Nilsson CE Nelson H Wolf TE Gamsky GT Bryan 1979 N-acetyltransferase phenotype and risk in urinary bladder cancer: approaches in molecular epidemiology. Preliminary results in Sweden and Denmark Environ Health Perspect 29 71 79 1:CAS:528:DyaE1MXktlOhs7w%3D 10.2307/3429048 510245 (Pubitemid 9190956)
8. PM Marcus P Vineis N Rothman 2000 NAT2 slow acetylation and bladder cancer risk: a meta-analysis of 22 case-control studies conducted in the general population Pharmacogenetics 10 115 122 1:CAS:528:DC%2BD3cXivVSjs7k%3D 10.1097/00008571-200003000-00003 10761999 (Pubitemid 30193073)
9. H Okkels T Sigsgaard H Wolf H Autrup 1997 Arylamine N-acetyltransferase 1 (NAT1) and 2 (NAT2) polymorphisms in susceptibility to bladder cancer: the influence of smoking Cancer Epidemiol Biomarkers Prev 6 225 231 1:CAS:528:DyaK2sXjtVais78%3D 9107426 (Pubitemid 27172886)
10. S Garte L Gaspari AK Alexandrie C Ambrosone H Autrup, et al. 2001 Metabolic gene polymorphism frequencies in control populations Cancer Epidemiol Biomarkers Prev 10 1239 1248 1:CAS:528:DC%2BD38XnsFSjsg%3D%3D 11751440 (Pubitemid 34027754)
11. LM Dong JD Potter E White CM Ulrich LR Cardon U Peters 2008 Genetic susceptibility to cancer: the role of polymorphisms in candidate genes JAMA 299 2423 2436 1:CAS:528:DC%2BD1cXmsFGitL4%3D 10.1001/jama.299.20.2423 18505952 (Pubitemid 351749241)
12. P Vineis H Bartsch N Caporaso AM Harrington FF Kadlubar, et al. 1994 Genetically based N-acetyltransferase metabolic polymorphism and low-level environmental exposure to carcinogens Nature 369 154 156 1:CAS:528: DyaK2cXktVejsbc%3D 10.1038/369154a0 7909916 (Pubitemid 24153439)
13. MC Yu PL Skipper K Taghizadeh SR Tannenbaum KK Chan, et al. 1994 Acetylator phenotype, aminobiphenyl-hemoglobin adduct levels, and bladder cancer risk in white, black and asian men in Los Angeles, California J Natl Cancer Inst 86 712 716 1:STN:280:DyaK2c3htVGmsQ%3D%3D 10.1093/jnci/86.9.712 8158701 (Pubitemid 24138978)
14. M Garcia-Closas N Malats D Silverman M Dosemeci M Kogevinas, et al. 2005 NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses Lancet 366 649 659 1:CAS:528:DC%2BD2MXosVajsb0%3D 10.1016/S0140-6736(05)67137-1 16112301 (Pubitemid 41176017)
15. PM Marcus RB Hayes P Vineis M Garcia-Closas NE Caporaso, et al. 2000 Cigarette smoking, N-acetyltransferase 2 acetylation status, and bladder cancer risk: a case-series meta-analysis of a gene-environment interaction Cancer Epidemiol Biomarkers Prev 9 461 467 1:CAS:528:DC%2BD3cXjslKgsrc%3D 10815690 (Pubitemid 30313888)
16. P Vineis D Marinelli H Autrup J Brockmöller I Cascorbi, et al. 2001 Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: a pooled analysis of genotype-based studies Cancer Epidemiol Biomarkers Prev 10 1249 1252 1:STN:280:DC%2BD38%2Fgt1SnsA%3D%3D 11751441 (Pubitemid 34027755)
17. J Green E Banks A Berrington S Darby H Deo R Newton 2000 N-acetyltransferase 2 and bladder cancer: an overview and consideration of the evidence for gene-environment interaction Br J Cancer 83 412 417 1:STN:280:DC%2BD3cznt1ahuw%3D%3D 10.1054/bjoc.2000.1265 10917561 (Pubitemid 30453586)
18. J Gu D Liang Y Wang C Lu X Wu 2005 Effects of N-acetyl transferase 1 and 2 polymorphisms on bladder cancer risk in Caucasians Mutat Res 581 97 104 1:CAS:528:DC%2BD2MXhslChtrY%3D 15725609 (Pubitemid 40255898)
19. RT Bryan SA Hussain ND James JA Jankowski MA Wallace 2005 Molecular pathways in bladder cancer: part 1 BJU Int 95 485 490 1:CAS:528: DC%2BD2MXis1Kgsr8%3D 10.1111/j.1464-410X.2005.05325.x 15705065 (Pubitemid 40311456)
20. E Kellen M Zeegers A Paulussen R Vlietinck EV Vlem, et al. 2007 Does occupational exposure to PAHs, diesel and aromatic amines interact with smoking and metabolic genetic polymorphisms to increase the risk of bladder cancer? The Belgian case control study on bladder cancer Cancer Lett 245 51 60 1:CAS:528:DC%2BD2sXht1emsA%3D%3D 10.1016/j.canlet.2005.12.025 16504378 (Pubitemid 46001500)
21. M Mcgrath D Michaud I De Vivo 2006 Polymorphisms in GSTT1, GSTM1, NAT1 and NAT2 genes and bladder cancer risk in men and women BMC Cancer 6 239 10.1186/1471-2407-6-239 17026750 (Pubitemid 44613106)
22. H Zhao J Lin JB Grossman LM Hernandez CP Dinney X Wu 2007 Dietary isothiocyanates, GSTM1, GSTT1, NAT2 polymorphisms and bladder cancer risk Int J Cancer 120 2208 2213 1:CAS:528:DC%2BD2sXkt1Oiu74%3D 10.1002/ijc.22549 17290402 (Pubitemid 46555860)
23. J Brockmöller I Cascorbi R Kerb I Roots 1996 Combined analysis of inherited polymorphisms in arylamine N-acetyltransferase 2, glutathione S-transferases M1 and T1, microsomal epoxide hydrolase, and cytochrome P450 enzymes as modulators of bladder cancer risk Cancer Res 56 3915 3925 8752158 (Pubitemid 26284739)
24. IF Filiadis I Georgiou Y Alamanos V Kranas X Giannakopoulos, et al. 1999 Genotypes of N-acetyltransferase-2 and risk of bladder cancer: a case-control study J Urol 161 1672 1675 1:STN:280:DyaK1M3isFWlsA%3D%3D 10.1016/S0022-5347(05) 69002-7 10210437 (Pubitemid 29420860)
25. SAJ Vaziri NC Hughes H Sampson G Darlington MAS Jewett DM Grant 2001 Variation in enzymes of arylamine procarcinogen biotransformation among bladder cancer patients and control subjects Pharmacogenetics 11 7 20 1:CAS:528:DC%2BD3MXhtFKhurc%3D 10.1097/00008571-200102000-00002 11207033 (Pubitemid 32108657)
26. Y Zang S Zhao MA Doll JC States DW Hein 2004 The T341C (Ile114Thr) polymorphism of N-acetyltransferase 2 yields slow acetylator phenotype by enhanced protein degradation Pharmacogenetics 14 717 723 1:CAS:528: DC%2BD2cXhtVais7%2FI 10.1097/00008571-200411000-00002 15564878 (Pubitemid 39552786)
27. E Schnakenberg M Lustig R Breuer R Werdin R Hübotter, et al. 2000 Gender-specific effects of NAT2 and GSTM1 in bladder cancer Clin Genet 57 270 277 1:STN:280:DC%2BD3cvls1OhtQ%3D%3D 10.1034/j.1399-0004.2000.570405.x 10845567 (Pubitemid 30235042)
28. Hein Heinx 2006 N-acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk Oncogene 25 1649 1658 10.1038/sj.onc.1209374
29. JA Taylor DM Umbach E Stephens T Castranio D Paulson, et al. 1998 The role of N-acetylation polymorphisms in smoking-associated bladder cancer: evidence of a gene-gene-exposure three-way interaction Cancer Res 58 3603 3610 1:CAS:528:DyaK1cXlsFajt7w%3D 9721868 (Pubitemid 28376558)
30. NP Lang FF Kadlubar 1991 Aromatic and heterocyclic amine metabolism and phenotyping in humans Prog Clin Biol Res 372 33 47 1:CAS:528:DyaK3sXhvVGit7w%3D 1956928
31. FF Kadlubar AF Badawi 1995 Genetic susceptibility and carcinogen-DNA adduct formation in human urinary bladder carcinogenesis Toxicol Lett 825 627 632 10.1016/0378-4274(95)03507-9 (Pubitemid 26057523)
32. DW Hein MA Doll AJ Fretland MA Leff SJ Webb, et al. 2000 Molecular genetics and epidemiology of the NAT1 and NAT2 acetylation polymorphisms Cancer Epidemiol Biomarkers Prev 9 29 42 1:CAS:528:DC%2BD3cXptVOmtA%3D%3D 10667461 (Pubitemid 30062907)
33. AF Badawi A Hirvonen DA Bell NP Lang FF Kadlubar 1995 Role of aromatic amine acetyltransferases, NAT1 and NAT2, in carcinogen-DNA adduct formation in the human urinary bladder Cancer Res 55 5230 5237 1:CAS:528:DyaK2MXpsVaru7w%3D 7585581
34. I Cascorbi I Roots J Brockmöller 2001 Association of NAT1 and NAT2 polymorphisms to urinary bladder cancer: significantly reduced risk in subjects with NAT1*10 Cancer Res 61 5051 5056 1:CAS:528:DC%2BD3MXltVequrk%3D 11431340 (Pubitemid 32681534)
35. DA Bell AF Badawi NP Lang KF Ilett FF Kadlubar A Hirvonen 1995 Polymorphism in the NAT1 polyadenylation signal: association of NAT1*10 allele with higher N-acetylation activity in bladder and colon tissue samples Cancer Res 55 5226 5229 1:CAS:528:DyaK2MXpsVaru78%3D 7585580
36. S Sanderson G Salanti J Higgins 2007 Joint effects of the N-Acetyltransferase 1 and 2 (NAT1 and NAT2) genes and smoking on bladder carcinogenesis: a literature-based systematic HuGE review and evidence synthesis Am J Epidemiol 166 741 751 10.1093/aje/kwm167 17675654 (Pubitemid 47428907)