-
1
-
-
78149347499
-
-
eds, 1975-2007. Bethesda, MD: National Cancer Institute. November, Accessed July 15, 2010
-
Altekruse SF, Kosary CL, Krapcho M, et al, eds. SEER Cancer Statistics Review, 1975-2007. Bethesda, MD: National Cancer Institute. November 2009. http://seer.cancer.gov/csr/1975_2007/. Accessed July 15, 2010.
-
(2009)
SEER Cancer Statistics Review
-
-
Altekruse, S.F.1
Kosary, C.L.2
Krapcho, M.3
-
2
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast tumours. Nature. 2000;406(6797):747-752.
-
(2000)
Nature
, vol.406
, Issue.6797
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
3
-
-
33847063053
-
The triple negative paradox: Primary tumor chemosensitivity of breast cancer subtypes
-
Carey LA, Dees EC, Sawyer L, et al. The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypes. Clin Cancer Res. 2007; 13(8):2329-2334.
-
(2007)
Clin Cancer Res
, vol.13
, Issue.8
, pp. 2329-2334
-
-
Carey, L.A.1
Dees, E.C.2
Sawyer, L.3
-
4
-
-
0023665111
-
5 kd phosphoprotein and phosphatidylinositol kinase activity
-
Kaplan DR, Whitman M, Schaffhausen B, et al. Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity. Cell. 1987;50(7): 1021-1029.
-
(1987)
Cell
, vol.50
, Issue.7
, pp. 1021-1029
-
-
Kaplan, D.R.1
Whitman, M.2
Schaffhausen, B.3
-
5
-
-
11144358645
-
3CA gene in human cancers
-
Samuels Y, Wang Z, Bardelli A, et al. High frequency of mutations of the PIK3CA gene in human cancers. Science. 2004;304(5670):554.
-
(2004)
Science
, vol.304
, Issue.5670
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
-
6
-
-
68249093818
-
Targeting the phosphoinositide 3-kinase pathway in cancer
-
Liu P, Cheng H, Roberts TM, Zhao JJ. Targeting the phosphoinositide 3-kinase pathway in cancer. Nat Rev Drug Discov. 2009;8(8):627-644.
-
(2009)
Nat Rev Drug Discov
, vol.8
, Issue.8
, pp. 627-644
-
-
Liu, P.1
Cheng, H.2
Roberts, T.M.3
Zhao, J.J.4
-
7
-
-
28244479028
-
3CA mutations are oncogenic in mammary epithelial cells
-
Isakoff SJ, Engelman JA, Irie HY, et al. Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells. Cancer Res. 2005; 65(23):10992-11000.
-
(2005)
Cancer Res
, vol.65
, Issue.23
, pp. 10992-11000
-
-
Isakoff, S.J.1
Engelman, J.A.2
Irie, H.Y.3
-
8
-
-
77953422867
-
3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer
-
Loi S, Haibe-Kains B, Majjaj S, et al. PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer. Proc Natl Acad Sci USA. 2010; 107(22):10208-10213.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.22
, pp. 10208-10213
-
-
Loi, S.1
Haibe-Kains, B.2
Majjaj, S.3
-
10
-
-
48649083369
-
85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers
-
85alpha and p110beta are essential for androgen receptor transactivation and tumor progression in prostate cancers. Oncogene. 2008;27(33):4569-4579.
-
(2008)
Oncogene
, vol.27
, Issue.33
, pp. 4569-4579
-
-
Zhu, Q.1
Youn, H.2
Tang, J.3
-
12
-
-
84855277725
-
A meta-analysis of gene expression profiling studies identifies clinically relevant oncogenic pathways in basal-like breast cancer
-
(Poster 106)
-
Ignatiadis M, Bedard P, Haibe-Kains B, et al. A meta-analysis of gene expression profiling studies identifies clinically relevant oncogenic pathways in basal-like breast cancer. San Antonio Breast Cancer Symposium (Poster 106). 2009.
-
(2009)
San Antonio Breast Cancer Symposium
-
-
Ignatiadis, M.1
Bedard, P.2
Haibe-Kains, B.3
-
13
-
-
0037352170
-
3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: A target for cancer chemotherapy
-
Chang F, Lee JT, Navolanic PM, et al. Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy. Leukemia. 2003;17(3):590-603.
-
(2003)
Leukemia
, vol.17
, Issue.3
, pp. 590-603
-
-
Chang, F.1
Lee, J.T.2
Navolanic, P.M.3
-
14
-
-
70349878470
-
3K signalling in colorectal cancer cell lines
-
Balmanno K, Chell SD, Gillings AS, Hayat S, Cook SJ. Intrinsic resistance to the MEK1/2 inhibitor AZD6244 (ARRY-142886) is associated with weak ERK1/2 signalling and/or strong PI3K signalling in colorectal cancer cell lines. International Journal of Cancer. 2009;125(10):2332-2341.
-
(2009)
International Journal of Cancer
, vol.125
, Issue.10
, pp. 2332-2341
-
-
Balmanno, K.1
Chell, S.D.2
Gillings, A.S.3
Hayat, S.4
Cook, S.J.5
-
15
-
-
51349164790
-
3K -dependent feedback loop in human cancer
-
Carracedo A, Ma L, Teruya-Feldstein J, et al. Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K -dependent feedback loop in human cancer. The Journal of Clinical Investigation. 2008;118(9):3065-3074.
-
(2008)
The Journal of Clinical Investigation
, vol.118
, Issue.9
, pp. 3065-3074
-
-
Carracedo, A.1
Ma, L.2
Teruya-Feldstein, J.3
-
16
-
-
85056021994
-
2 therapy [abstract 522]
-
Loi S, Haibe-Kains B, Brown DN, et al. Correlation of molecular and clinically distinct phenotypes in HER2-overexpressing breast cancer (HER2+ BC) with estrogen receptor status (ER) status: implications for anti-HER2 therapy [abstract 522]. J Clin Oncol. 2010;28 (suppl):7s.
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL.
-
-
Loi, S.1
Haibe-Kains, B.2
Brown, D.N.3
-
17
-
-
68049085887
-
In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models
-
Hoeflich KP, O'Brien C, Boyd Z, et al. In vivo antitumor activity of MEK and phosphatidylinositol 3-kinase inhibitors in basal-like breast cancer models. Clin Cancer Res. 2009;15(14):4649-4664.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.14
, pp. 4649-4664
-
-
Hoeflich, K.P.1
O'Brien, C.2
Boyd, Z.3
-
18
-
-
73549121061
-
Effects of combined inhibition of MEK and mTOR on downstream signaling and tumor growth in pancreatic cancer xenograft models
-
Chang Q, Chen E, Hedley DW. Effects of combined inhibition of MEK and mTOR on downstream signaling and tumor growth in pancreatic cancer xenograft models. Cancer Biology & Therapy. 2009;8(20):1893-1901.
-
(2009)
Cancer Biology & Therapy
, vol.8
, Issue.20
, pp. 1893-1901
-
-
Chang, Q.1
Chen, E.2
Hedley, D.W.3
-
20
-
-
77955460676
-
Firms combine experimental cancer drugs to speed development
-
Sheridan C. Firms combine experimental cancer drugs to speed development. Nature Biotechnology. 2010;28(8):765-766.
-
(2010)
Nature Biotechnology
, vol.28
, Issue.8
, pp. 765-766
-
-
Sheridan, C.1
-
21
-
-
77951206427
-
Triple-negative breast cancer: Molecular features, pathogenesis, treatment and current lines of research
-
Bosch A, Eroles P, Zaragoza R, Vina JR, Lluch A. Triple-negative breast cancer: molecular features, pathogenesis, treatment and current lines of research. Cancer Treatment Reviews. 2010;36(3):206-215.
-
(2010)
Cancer Treatment Reviews
, vol.36
, Issue.3
, pp. 206-215
-
-
Bosch, A.1
Eroles, P.2
Zaragoza, R.3
Vina, J.R.4
Lluch, A.5
-
22
-
-
77955019276
-
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: A proof-of-concept trial
-
Tutt A, Robson M, Garber JE, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial. Lancet. 2010;376(9737): 235-244.
-
(2010)
Lancet
, vol.376
, Issue.9737
, pp. 235-244
-
-
Tutt, A.1
Robson, M.2
Garber, J.E.3
|