Novel allelic variants in the canine Cyclooxgenase-2 (Cox-2) promoter are associated with renal dysplasia in dogs

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Whiteley, Mary H ^a   Bell, Jerold S ^b   Rothman, Debby A ^c  

^a DOGenes Inc   (Canada)

^b TUFTS UNIVERSITY   (United States)

^c American Lhasa Apso Club   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; CIS ACTING ELEMENT; CYCLOOXYGENASE 2; CYTOSINE; DNA; GUANINE; THYMINE; TRANSCRIPTION FACTOR SP1;

ALLELE; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; BREED DIFFERENCE; CONTROLLED STUDY; DISEASE SEVERITY; DOG; ENVIRONMENTAL FACTOR; GENE DELETION; GENE EXPRESSION; GENE INSERTION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; INHERITANCE; KIDNEY DYSPLASIA; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PEDIGREE ANALYSIS; PROMOTER REGION; REGULATORY SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSLATION INITIATION; ANIMAL; ANIMAL DISEASE; BREEDING; DNA SEQUENCE; DOG DISEASE; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; KIDNEY DISEASE; METABOLISM; MUTATION; PEDIGREE; SPECIES DIFFERENCE;

CANIS FAMILIARIS; MUS;

ALLELES; ANIMALS; BINDING SITES; BREEDING; CYCLOOXYGENASE 2; DOG DISEASES; DOGS; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; KIDNEY DISEASES; MUTATION; PEDIGREE; PROMOTER REGIONS, GENETIC; SEQUENCE ANALYSIS, DNA; SEQUENCE DELETION; SP1 TRANSCRIPTION FACTOR; SPECIES SPECIFICITY;

EID: 79951565644     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016684     Document Type: Article

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