A myomesin mutation associated with hypertrophic cardiomyopathy deteriorates dimerisation properties

Biochemical and Biophysical Research Communications

Volumn 405, Issue 3, 2011, Pages 473-479

  Siegert, Romy ^a   Perrot, Andreas ^b   Keller, Sandro ^c   Behlke, Joachim ^a   Michalewska Włudarczyk, Aleksandra ^d   Wycisk, Anna ^d   Tendera, Michal ^d   Morano, Ingo ^a   Özcelik, Cemil ^b  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c France   (Germany)

^d MEDICAL UNIVERSITY OF SILESIA   (Poland)

Author keywords

Analytical ultracentrifugation; Hypertrophic cardiomyopathy; Mutation; Myomesin; Protein structure; Protein protein interaction

Indexed keywords

DIMER; MONOMER; MYOMESIN; PEPTIDE FRAGMENT;

ADULT; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DIMERIZATION; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; FEMALE; GENETIC ASSOCIATION; GENETIC SCREENING; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN STRUCTURE; SPECTROSCOPY; SURFACE PLASMON RESONANCE; THERMOSTABILITY; ULTRACENTRIFUGATION; WILD TYPE;

ADULT; CARDIOMYOPATHY, HYPERTROPHIC; FEMALE; HUMANS; MALE; MIDDLE AGED; MUSCLE PROTEINS; MUTATION, MISSENSE; PEDIGREE; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; SURFACE PLASMON RESONANCE;

EID: 79951561937     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.01.056     Document Type: Article

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