A comparison of postprocedural wound care treatments: Do antibiotic-based ointments improve outcomes?

Journal of the American Academy of Dermatology

Volumn 64, Issue 3 SUPPL. 1, 2011, Pages

  Draelos, Zoe D ^a   Rizer, Ronald L ^b   Trookman, Nathan S ^c  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Thomas J Stephens and Associates   (United States)

^c Dermatologic Surgery Unit   (United States)

Author keywords

Aquaphor; bacitracin zinc; dermatologic procedures; polymyxin B sulfate; Polysporin; seborrheic keratoses; superficial wounds; wound care; wound healing

Indexed keywords

AHO; AQUAPHOR HEALING OINTMENT; BACITRACIN ZINC PLUS POLYMYXIN B; POLY BAC; UNCLASSIFIED DRUG; WOUND HEALING PROMOTING AGENT;

ADULT; ADVERSE OUTCOME; AGED; ANTIBIOTIC RESISTANCE; APPLICATION SITE BURNING; APPLICATION SITE EDEMA; APPLICATION SITE ERYTHEMA; APPLICATION SITE IRRITATION; APPLICATION SITE PAIN; APPLICATION SITE PIGMENTATION CHANGE; APPLICATION SITE PRURITUS; APPLICATION SITE SCABBING; ARTICLE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG SAFETY; FEMALE; HUMAN; INTERMETHOD COMPARISON; MALE; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEBORRHEIC KERATOSIS; SKIN ALLERGY; SKIN BURNING SENSATION; SKIN INJURY; SKIN IRRITATION; SKIN SURGERY; SKIN TIGHTNESS; TREATMENT OUTCOME; WOUND CARE; WOUND HEALING;

BACITRACIN; DERMATITIS, ALLERGIC CONTACT; DOUBLE-BLIND METHOD; DRUG RESISTANCE, MICROBIAL; HUMANS; KERATOSIS, SEBORRHEIC; OINTMENTS; PETROLATUM; POLYMYXIN B; SKIN IRRITANCY TESTS; TREATMENT OUTCOME; WOUND HEALING;

EID: 79951553758     PISSN: 01909622     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaad.2010.11.010     Document Type: Article

References (34)

1. C.J. Weber Update on antimicrobial resistance Dermatol Nurs 18 2006 15 18
2. J.Q. Del Rosso, and J.J. Leyden Status report on antibiotic resistance: implications for the dermatologist Dermatol Clin 25 2007 127 132 v (Pubitemid 46566394)
3. C.K. Field, and M.D. Kerstein Overview of wound healing in a moist environment Am J Surg 167 Suppl 1994 2S 6S
4. V.M. Sheth, and S. Weitzul Postoperative topical antimicrobial use Dermatitis 19 2008 181 189
5. C.T. Spann, S.C. Taylor, and J.M. Weinberg Topical antimicrobial agents in dermatology Dis Mon 50 2004 407 421
6. M.J. Messingham, and C.J. Arpey Update on the use of antibiotics in cutaneous surgery Dermatol Surg 31 2005 1068 1078 (Pubitemid 44796346)
7. G.B. Forbes Staphylococcal infection of operation wounds with special reference to topical antibiotic prophylaxis Lancet 2 1961 505 509
8. C. Heisterkamp III, J. Vernick, R.L. Simmons, and T. Motsumoto Topical antibiotics in war wounds: a re-evaluation Mil Med 134 1969 13 18
9. R.G. Geronemus, P.M. Mertz, and W.H. Eaglstein Wound healing: the effects of topical antimicrobial agents Arch Dermatol 115 1979 1311 1314 (Pubitemid 10156827)
10. J.H. Langford, P. Artemi, and S.I. Benrimoj Topical antimicrobial prophylaxis in minor wounds Ann Pharmacother 31 1997 559 563 (Pubitemid 27203952)
11. J.Q. Del Rosso, and G.K. Kim Topical antibiotics: therapeutic value or ecologic mischief? Dermatol Ther 22 2009 398 406
12. D.C. Whitaker, D.J. Grande, and S.S. Johnson Wound infection rate in dermatologic surgery J Dermatol Surg Oncol 14 1988 525 528
13. D.P. Smack, A.C. Harrington, C. Dunn, R.S. Howard, A.J. Szkutnik, and S.J. Krivda Infection and allergy incidence in ambulatory surgery patients using white petrolatum vs bacitracin ointment: a randomized controlled trial JAMA 276 1996 972 977 (Pubitemid 26318227)
14. R.M. Campbell, C.S. Perlis, E. Fisher, and H.M. Gloster Jr. Gentamicin ointment versus petrolatum for management of auricular wounds Dermatol Surg 31 2005 664 669 (Pubitemid 43093422)
15. K.A. Gehrig, and E.M. Warshaw Allergic contact dermatitis to topical antibiotics: epidemiology, responsible allergens, and management J Am Acad Dermatol 58 2008 1 21 (Pubitemid 350298144)
16. H. Möller Eczematous contact allergy to oxytetracycline and polymyxin B Contact Dermatitis 2 1976 289 290
17. M.M. Jiaravuthisan, and J.G. DeKoven Contact dermatitis to polymyxin B Contact Dermatitis 59 2008 314 316
18. J.L. Ross, A.M. Snelling, E. Carnegie, P. Coates, W.J. Cunliffe, and V. Bettoli Antibiotic-resistant acne: lessons from Europe Br J Dermatol 148 2003 467 478 (Pubitemid 36461325)
19. E.A. Eady, M. Gloor, and J.J. Leyden Propionibacterium acnes resistance: a worldwide problem Dermatology 206 2003 54 56 (Pubitemid 36164666)
20. Anonymous Recent trends in antimicrobial resistance among Streptococcus pneumoniae and Staphylococcus aureus isolates: the French experience Euro Surveill 13 2008 1 6
21. Food and Drug Administration, Health and Human Services Skin protectant drug products for over-the-counter human use; final monograph: final rule Fed Regist 68 2003 33362 33381
22. B. Gupta, P. Arora, V.S. Singh, and S.K. Bhargava Topical amiloride ointment accelerates healing of mechanical skin ulcers in albino rabbits and patients Methods Find Exp Clin Pharmacol 28 2006 101 107
23. E. Moisidis, T. Heath, C. Boorer, K. Ho, and A.K. Deva A prospective, blinded, randomized, controlled clinical trial of topical negative pressure use in skin grafting Plast Reconstr Surg 114 2004 917 922 (Pubitemid 40362106)
24. M. Rendon, L. Cardona, and A. Benitez The safety and efficacy of trolamine/sodium alginate topical emulsion in postlaser resurfacing wounds J Drugs Dermatol 5 Suppl 2008 S23 S28
25. A.J. Dixon, M.P. Dixon, and J.B. Dixon Randomized clinical trial of the effect of applying ointment to surgical wounds before occlusive dressing Br J Surg 93 2006 937 943 (Pubitemid 44214843)
26. M.D. Pratt, D.V. Belsito, V.A. DeLeo, J.F. Fowler Jr., A.F. Fransway, and H.I. Maibach North American Contact Dermatitis Group patch-test results, 2001-2002 study period Dermatitis 15 2004 176 183 (Pubitemid 40250266)
27. K.A. Zug, E.M. Warshaw, J.F. Fowler Jr., H.I. Maibach, D.L. Belsito, and M.D. Pratt Patch-test results of the North American Contact Dermatitis Group 2005-2006 Dermatitis 20 2009 149 160
28. A.E. Aiello, E.L. Larson, and S.B. Levy Consumer antibacterial soaps: effective or just risky? Clin Infect Dis 45 Suppl 2007 S137 S147
29. J.E. Sebben Sterile technique and the prevention of wound infection in office surgery-part II J Dermatol Surg Oncol 15 1989 38 48 (Pubitemid 19050622)
30. H. Rosengren, and A. Dixon Antibacterial prophylaxis in dermatologic surgery: an evidence-based review Am J Clin Dermatol 11 2010 35 44
31. G.A. Kannon, and A.B. Garrett Moist wound healing with occlusive dressings: a clinical review Dermatol Surg 21 1995 583 590
32. P.M. Mertz, and L.G. Ovington Wound healing microbiology Dermatol Clin 11 1993 739 747 (Pubitemid 23313918)
33. H.C. Polk Jr., C.J. Simpson, B.P. Simmons, and J.W. Alexander Guidelines for prevention of surgical wound infection Arch Surg 118 1983 1213 1217 (Pubitemid 13005838)
34. B. Kim, and W. James Postoperative use of topical antimicrobials Dermatitis 20 2009 174