Purification and characterization of a mucin-binding mycelial lectin from Aspergillus nidulans with potent mitogenic activity

World Journal of Microbiology and Biotechnology

Volumn 27, Issue 3, 2011, Pages 547-554

  Singh, Ram Sarup ^a   Bhari, Ranjeeta ^a   Singh, Jatinder ^b   Tiwary, Ashok Kumar ^a  

^a PUNJABI UNIVERSITY   (India)

^b GURU NANAK DEV UNIVERSITY   (India)

Author keywords

Aspergillus nidulans; Haemagglutination; Lectin; Mitogenic potential; Mucin binding; Purification

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; ASPERGILLUS; PURIFICATION; UREA;

ASPERGILLUS NIDULANS; HAEMAGGLUTINATION; LECTIN; MITOGENIC; MUCIN-BINDING;

PROTEINS;

ASPERGILLUS; ASPERGILLUS SP.; EMERICELLA NIDULANS;

EID: 79951551612     PISSN: 09593993     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11274-010-0488-2     Document Type: Article

References (40)

1. Bhowal J, Guha AK, Chatterjee BP (2005) Purification and molecular characterization of a sialic acid specific lectin from phytopathogenic fungus Macrophomina phaseolina. Carbohydr Res 340: 1973-1982.
2. Candy L, Peumans WJ, Menu-Bouaouiche L, Astoul CH, van Damme J, van Damme EJM, Erard M, Rougé P (2001) The Gal/GalNAc-specific lectin from the phytopathogenic Basidiomycete Rhizoctonia solani is a member of the ricin-B family. Biochem Biophys Res Commun 282: 655-661.
3. Candy L, van Damme EJM, Peumans WJ, Menu-Bouaouiche L, Erard M, Rougé P (2003) Structural and functional characterization of the GalNAc/Gal-specific lectin from the phytopathogenic Ascomycete Sclerotinia sclerotiorum (Lib.) de Bary. Biochem Biophys Res Commun 308: 396-402.
4. Greene WC, Waldmann TA (1980) Inhibition of human lymphocyte proliferation by the non-mitogenic lectin wheat germ agglutinin. J Immunol 124: 2979-2987.
5. Greene WC, Fleisher TA, Waldmann TA (1981) Suppression of human T and B lymphocyte activation by Agaricus bisporus lectin. J Immunol 126: 580-586.
6. Hamilton AJ, Jeavons L, Youngchim S, Vanittankam N, Hay RJ (1998) Sialic acid-dependent recognition of laminin by Penicillium marneffei conidia. Infect Immun 66: 6024-6026.
7. Hedge JE, Hofreiter BT (1962) Estimation of carbohydrates. In: Whistler RL, BeMiller JN (eds) Carbohydrate chemistry, vol 17. Academic Press, New York, pp 17-22.
8. Ho JCK, Sze SCW, Shen WZ, Liu WK (2004) Mitogenic activity of edible mushroom lectins. Biochim Biophys Acta 1671: 9-17.
9. Ishimaru T, Bernard EM, Tamada S, Armstrong D (1996) The fucose-specific lectin (FSL) produced by Aspergillus fumigatus may promote attachment of conidia to mammalian cells. In: Abstracts of the IDSA 34th Annual Meeting, p 206.
10. Jung EC, Kim KD, Bae CH, Kim JC, Kim DK, Kim HH (2007) A mushroom lectin from Ascomycete Cordyceps militaris. Biochim Biophys Acta 1770: 833-838.
11. Khan F, Ahmad A, Khan MI (2007) Purification and characterization of a lectin from endophytic fungus Fusarium solani having complex sugar specificity. Arch Biochem Biophys 457: 243-251.
12. Kilpatrick DC (1991) Lectin interactions with human leukocytes: Mitogenecity, cell separation, clinical applications. In: Kilpatrick DC, van Driessche E, Bog TC (eds) Lectin reviews. Sigma Chemical Co, St Louis, pp 69-80.
13. Krickeberg H, Mauff G, Mertens T, Plum G, Heitmann K (1990) Lymphocyte proliferation in AIDS-related complex/Walter-Reed 5 patients: Response to herpes simplex virus and tuberculin antigen and mitogen during intravenous immunoglobulin treatment. Vox Sang 59: 38-43.
14. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
15. Liu QH, Wang HX, Ng TB (2006) First report of a xylose-specific lectin with potent hemagglutinating, antiproliferative and anti-mitogenic activities from a wild ascomycete mushroom. Biochim Biophys Acta 1760: 1914-1919.
16. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein estimation with Folin-phenol reagent. J Biol Chem 193: 265-275.
17. Mahajan RG, Patil SI, Mohan DRK, Shastry P (2002) Pleurotus eous mushroom lectin with mixed carbohydrate inhibition and antiproliferative activity on tumor cell lines. J Biochem Mol Biol Biophys 6: 341-345.
18. Mandal C, Mandal C (1990) Sialic acid binding lectins. Experientia 46: 433-441.
19. Matsumoto I, Osawa T (1972) The specific purification of various carbohydrate-binding hemagglutinins. Biochem Biophys Res Commun 46: 1810-1815.
20. Matsumura K, Higashida K, Ishida H, Hata Y, Yamamoto K, Shigeta M, Mizuno-Horikawa Y, Wang X, Miyoshi E, Gu J, Taniguchi N (2007) Carbohydrate-binding specificity of a fucose-specific lectin from Aspergillus oryzae: a novel probe for core fucose. J Biol Chem 282: 15700-15708.
21. Nelson DL, Cox MN (2001) Lehninger principles of biochemistry, 3rd edn. Worth Publishers, New York, pp 159-202.
22. Ngai PHK, Ng TB (2004) A mushroom (Ganoderma capense) lectin with spectacular thermostability, potent mitogenic activity on splenocytes and antiproliferative activity towards tumor cells. Biochem Biophys Res Commun 314: 988-993.
23. 2+ binding to the lima bean lectins. J Biol Chem 255: 870-873.
24. Rosen S, Ek B, Rask L, Tunlid A (1992) Purification and characterization of a surface lectin from nematode-trapping fungus Arthrobotrys oligospora. J Gen Microbiol 138: 2663-2672.
25. Singh RS, Tiwary AK, Kennedy JF (1999) Lectins: sources, activities and applications. Crit Rev Biotechnol 19: 145-178.
26. Singh RS, Tiwary AK, Bhari R (2008) Screening of Aspergillus species for occurrence of lectins and their characterization. J Basic Microbiol 48: 112-117.
27. Singh RS, Sharma S, Kaur G, Bhari R (2009a) Screening of Penicillium species for occurrence of lectins and their characterization. J Basic Microbiol 49: 471-476.
28. Singh RS, Thakur G, Bhari R (2009b) Optimization of culture conditions and characterization of a new lectin from Aspergillus niger. Ind J Microbiol 49: 219-222.
29. Singh RS, Bhari R, Kaur HP (2010a) Current trends of lectins from microfungi. Crit Rev Biotechnol. (Accepted).
30. Singh RS, Bhari R, Kaur HP (2010b) Mushroom lectins: current status and future perspectives. Crit Rev Biotechnol 30: 99-126.
31. Singh RS, Bhari R, Rai J (2010c) Further screening of Aspergillus species for occurrence of lectins and their partial characterization. J Basic Microbiol 50: 90-97.
32. Singh RS, Bhari R, Kaur HP, Vig M (2010d) Purification and characterization of a novel thermostable mycelial lectin from Aspergillus terricola. Appl Biochem Biotechnol. doi: 10. 1007/s2010-009-8906-3s.
33. Tiwary AK, Singh RS (1998) Lectins as tumor cell specific and drug targeting molecules. Res Bull Panjab Univ 48: 55-85.
34. Tiwary AK, Singh RS (1999) Lectins: novel drug targeting molecules. Ind J Pharm Sci 61: 259-267.
35. Tronchin G, Esnault K, Sanchez M, Larcher G, Marot-Leblond A, Bouchara J-P (2002) Purification and partial characterization of a 32-kilodalton sialic acid-specific lectin from Aspergillus fumigatus. Infect Immun 70: 6891-6895.
36. Wang JL, McClain DA, Edelman GM (1975) Modulation of lymphocyte mitogenesis. Proc Nat Acad Sci USA 72: 1917-1921.
37. Wang HX, Ng TB, Ooi VE (1998) Lectin activity in fruiting bodies of the edible mushroom Tricholoma mongolicum. Biochem Mol Biol Int 44: 135-141.
38. Wong JH, Wang H, Ng TB (2009) A hemagglutinin from the medicinal fungus Cordyceps militaris. Biosci Reports 29: 321-327.
39. Wu AM, Wu JH, Tsai MS, Hedge GV, Inamdar SR, Swamy BM, Herp A (2001) Carbohydrate specificity of a lectin isolated from the fungus Sclerotium rolfsii. Life Sci 69: 2039-2050.
40. Xiong C, Li W, Liu H, Zhang W, Dou J, Bai X, Du Y, Ma X (2006) A normal mucin-binding lectin from the sponge Craniella australiensis. Comp Biochem Physiol C Toxicol Pharmacol 143: 9-16.