Two dileucine motifs mediate late endosomal/lysosomal targeting of transmembrane protein 192 (TMEM192) and a C-terminal cysteine residue is responsible for disulfide bond formation in TMEM192 homodimers

Biochemical Journal

Volumn 434, Issue 2, 2011, Pages 219-231

  Behnke, Jörg ^a   Eskelinen, Eeva Liisa ^b   Saftig, Paul ^a   Schröder, Bernd ^a  

^a UNIVERSITY OF KIEL   (Germany)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Dileucine motif; Disulfide bridge; Late endosome; Lysosomal targeting; Lysosome; Organellar proteomics; Transmembrane protein 192 (TMEM192)

Indexed keywords

CYSTEINE; HOMODIMER; LEUCINE; MEMBRANE PROTEIN; PROTEINASE; TRANSMEMBRANE PROTEIN 192; UNCLASSIFIED DRUG;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CHIMERA; CYTOSOL; DIMERIZATION; DISULFIDE BOND; ENDOSOME; LYSOSOME; LYSOSOME MEMBRANE; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN TARGETING; PROTEOMICS;

AMINO ACID MOTIFS; CYSTEINE; DIMERIZATION; DISULFIDES; ENDOSOMES; HUMANS; LEUCINE; LYSOSOMES; MEMBRANE PROTEINS; PROTEIN FOLDING; PROTEIN SORTING SIGNALS; PROTEIN STRUCTURE, TERTIARY;

EID: 79951524031     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20101396     Document Type: Article

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