-
1
-
-
67649870457
-
The Tbx2+ primary myocardium of the atrioventricular canal forms the atrioventricular node and the base of the left ventricle
-
Aanhaanen W.T., Brons J.F., Domínguez J.N., et al. The Tbx2+ primary myocardium of the atrioventricular canal forms the atrioventricular node and the base of the left ventricle. Circ Res 2009, 104:1267-1274.
-
(2009)
Circ Res
, vol.104
, pp. 1267-1274
-
-
Aanhaanen, W.T.1
Brons, J.F.2
Domínguez, J.N.3
-
2
-
-
44949102430
-
Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system
-
Bakker M.L., Boukens B.J., Mommersteeg M.T., et al. Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system. Circ Res 2008, 102:1340-1349.
-
(2008)
Circ Res
, vol.102
, pp. 1340-1349
-
-
Bakker, M.L.1
Boukens, B.J.2
Mommersteeg, M.T.3
-
3
-
-
0030986873
-
Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome
-
Bamshad M., Lin R.C., Law D.J., et al. Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome. Nat Genet 1997, 16:311-315.
-
(1997)
Nat Genet
, vol.16
, pp. 311-315
-
-
Bamshad, M.1
Lin, R.C.2
Law, D.J.3
-
4
-
-
8444245525
-
A phylogenetically conserved cis-regulatory module in the Msx2 promoter is sufficient for BMP-dependent transcription in murine and Drosophila embryos
-
Brugger S.M., Merrill A.E., Torres-Vazquez J., et al. A phylogenetically conserved cis-regulatory module in the Msx2 promoter is sufficient for BMP-dependent transcription in murine and Drosophila embryos. Development 2004, 131:5153-5165.
-
(2004)
Development
, vol.131
, pp. 5153-5165
-
-
Brugger, S.M.1
Merrill, A.E.2
Torres-Vazquez, J.3
-
5
-
-
17944378083
-
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease
-
Bruneau B.G., Nemer G., Schmitt J.P., et al. A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease. Cell 2001, 106:709-721.
-
(2001)
Cell
, vol.106
, pp. 709-721
-
-
Bruneau, B.G.1
Nemer, G.2
Schmitt, J.P.3
-
6
-
-
33644680809
-
Building the mammalian heart from two sources of myocardial cells
-
Buckingham M., Meilhac S., Zaffran S. Building the mammalian heart from two sources of myocardial cells. Nat Rev Genet 2005, 6:826-835.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 826-835
-
-
Buckingham, M.1
Meilhac, S.2
Zaffran, S.3
-
7
-
-
21044454606
-
T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis
-
Cai C.L., Zhou W., Yang L., et al. T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development 2005, 132:2475-2487.
-
(2005)
Development
, vol.132
, pp. 2475-2487
-
-
Cai, C.L.1
Zhou, W.2
Yang, L.3
-
8
-
-
41149162273
-
Foxn4 directly regulates tbx2b expression and atrioventricular canal formation
-
Chi N.C., Shaw R.M., De Val S., et al. Foxn4 directly regulates tbx2b expression and atrioventricular canal formation. Genes Dev 2008, 22:734-739.
-
(2008)
Genes Dev
, vol.22
, pp. 734-739
-
-
Chi, N.C.1
Shaw, R.M.2
De Val, S.3
-
9
-
-
21044459960
-
Architectural plan for the heart: early patterning and delineation of the chambers and the nodes
-
Christoffels V.M., Burch J.B., Moorman A.F. Architectural plan for the heart: early patterning and delineation of the chambers and the nodes. Trends Cardiovasc Med 2004, 14:301-307.
-
(2004)
Trends Cardiovasc Med
, vol.14
, pp. 301-307
-
-
Christoffels, V.M.1
Burch, J.B.2
Moorman, A.F.3
-
10
-
-
1842561719
-
T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers
-
Christoffels V.M., Hoogaars W.M., Tessari A., Clout D.E., Moorman A.F., Campione M. T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers. Dev Dyn 2004, 229:763-770.
-
(2004)
Dev Dyn
, vol.229
, pp. 763-770
-
-
Christoffels, V.M.1
Hoogaars, W.M.2
Tessari, A.3
Clout, D.E.4
Moorman, A.F.5
Campione, M.6
-
11
-
-
67649503019
-
Tbx1 regulates the BMP-Smad1 pathway in a transcription independent manner
-
Fulcoli F.G., Huynh T., Scambler P.J., Baldini A. Tbx1 regulates the BMP-Smad1 pathway in a transcription independent manner. PLoS One 2009, 4:e6049.
-
(2009)
PLoS One
, vol.4
-
-
Fulcoli, F.G.1
Huynh, T.2
Scambler, P.J.3
Baldini, A.4
-
12
-
-
0037093383
-
Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation
-
Habets P.E., Moorman A.F., Clout D.E., et al. Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation. Genes Dev 2002, 16:1234-1246.
-
(2002)
Genes Dev
, vol.16
, pp. 1234-1246
-
-
Habets, P.E.1
Moorman, A.F.2
Clout, D.E.3
-
13
-
-
8444252934
-
Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development
-
Harrelson Z., Kelly R.G., Goldin S.N., et al. Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development. Development 2004, 131:5041-5052.
-
(2004)
Development
, vol.131
, pp. 5041-5052
-
-
Harrelson, Z.1
Kelly, R.G.2
Goldin, S.N.3
-
14
-
-
33947522170
-
T-box factors determine cardiac design
-
Hoogaars W.M., Barnett P., Moorman A.F., Christoffels V.M. T-box factors determine cardiac design. Cell Mol Life Sci 2007, 64:646-660.
-
(2007)
Cell Mol Life Sci
, vol.64
, pp. 646-660
-
-
Hoogaars, W.M.1
Barnett, P.2
Moorman, A.F.3
Christoffels, V.M.4
-
15
-
-
43549088089
-
TBX3 and its splice variant TBX3 + exon 2a are functionally similar
-
Hoogaars W.M., Barnett P., Rodriguez M., et al. TBX3 and its splice variant TBX3 + exon 2a are functionally similar. Pigment Cell Melanoma Res 2008, 21:379-387.
-
(2008)
Pigment Cell Melanoma Res
, vol.21
, pp. 379-387
-
-
Hoogaars, W.M.1
Barnett, P.2
Rodriguez, M.3
-
16
-
-
34247590280
-
Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria
-
Hoogaars W.M., Engel A., Brons J.F., et al. Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria. Genes Dev 2007, 21:1098-1112.
-
(2007)
Genes Dev
, vol.21
, pp. 1098-1112
-
-
Hoogaars, W.M.1
Engel, A.2
Brons, J.F.3
-
17
-
-
2442513900
-
The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart
-
Hoogaars W.M., Tessari A., Moorman A.F., et al. The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart. Cardiovasc Res 2004, 62:489-499.
-
(2004)
Cardiovasc Res
, vol.62
, pp. 489-499
-
-
Hoogaars, W.M.1
Tessari, A.2
Moorman, A.F.3
-
18
-
-
34547738523
-
Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy
-
Kirk E.P., Sunde M., Costa M.W., et al. Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. Am J Hum Genet 2007, 81:280-291.
-
(2007)
Am J Hum Genet
, vol.81
, pp. 280-291
-
-
Kirk, E.P.1
Sunde, M.2
Costa, M.W.3
-
19
-
-
36749013666
-
Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis
-
Klaus A., Saga Y., Taketo M.M., Tzahor E., Birchmeier W. Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis. Proc Natl Acad Sci U S A 2007, 104:18531-18536.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 18531-18536
-
-
Klaus, A.1
Saga, Y.2
Taketo, M.M.3
Tzahor, E.4
Birchmeier, W.5
-
20
-
-
33947309902
-
Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2
-
Kokubo H., Tomita-Miyagawa S., Hamada Y., Saga Y. Hesr1 and Hesr2 regulate atrioventricular boundary formation in the developing heart through the repression of Tbx2. Development 2007, 134:747-755.
-
(2007)
Development
, vol.134
, pp. 747-755
-
-
Kokubo, H.1
Tomita-Miyagawa, S.2
Hamada, Y.3
Saga, Y.4
-
21
-
-
1842413728
-
Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family
-
Li Q.Y., Newbury-Ecob R.A., Terrett J.A., et al. Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. Nat Genet 1997, 15:21-29.
-
(1997)
Nat Genet
, vol.15
, pp. 21-29
-
-
Li, Q.Y.1
Newbury-Ecob, R.A.2
Terrett, J.A.3
-
22
-
-
31144440253
-
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning
-
Ma L., Lu M.F., Schwartz R.J., Martin J.F. Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning. Development 2005, 132:5601-5611.
-
(2005)
Development
, vol.132
, pp. 5601-5611
-
-
Ma, L.1
Lu, M.F.2
Schwartz, R.J.3
Martin, J.F.4
-
23
-
-
77952201846
-
The BMP pathway acts to directly regulate Tbx20 in the developing heart
-
Mandel E.M., Kaltenbrun E., Callis T.E., et al. The BMP pathway acts to directly regulate Tbx20 in the developing heart. Development 2010, 137:1919-1929.
-
(2010)
Development
, vol.137
, pp. 1919-1929
-
-
Mandel, E.M.1
Kaltenbrun, E.2
Callis, T.E.3
-
24
-
-
33644852924
-
Novel TBX3 mutation data in families with Ulnar-Mammary syndrome indicate a genotype-phenotype relationship: mutations that do not disrupt the T-domain are associated with less severe limb defects
-
Meneghini V., Odent S., Platonova N., Egeo A., Merlo G.R. Novel TBX3 mutation data in families with Ulnar-Mammary syndrome indicate a genotype-phenotype relationship: mutations that do not disrupt the T-domain are associated with less severe limb defects. Eur J Med Genet 2006, 49:151-158.
-
(2006)
Eur J Med Genet
, vol.49
, pp. 151-158
-
-
Meneghini, V.1
Odent, S.2
Platonova, N.3
Egeo, A.4
Merlo, G.R.5
-
25
-
-
33847020703
-
Molecular pathway for the localized formation of the sinoatrial node
-
Mommersteeg M.T., Hoogaars W.M., Prall O.W., et al. Molecular pathway for the localized formation of the sinoatrial node. Circ Res 2007, 100:354-362.
-
(2007)
Circ Res
, vol.100
, pp. 354-362
-
-
Mommersteeg, M.T.1
Hoogaars, W.M.2
Prall, O.W.3
-
26
-
-
3543053797
-
Spatio-temporal activation of Smad1 and Smad5 in vivo: monitoring transcriptional activity of Smad proteins
-
Monteiro R.M., de Sousa Lopes S.M., Korchynskyi O., et al. Spatio-temporal activation of Smad1 and Smad5 in vivo: monitoring transcriptional activity of Smad proteins. J Cell Sci 2004, 117:4653-4663.
-
(2004)
J Cell Sci
, vol.117
, pp. 4653-4663
-
-
Monteiro, R.M.1
de Sousa Lopes, S.M.2
Korchynskyi, O.3
-
27
-
-
28844496577
-
T-box genes in vertebrate development
-
Naiche L.A., Harrelson Z., Kelly R.G., Papaioannou V.E. T-box genes in vertebrate development. Annu Rev Genet 2005, 39:219-239.
-
(2005)
Annu Rev Genet
, vol.39
, pp. 219-239
-
-
Naiche, L.A.1
Harrelson, Z.2
Kelly, R.G.3
Papaioannou, V.E.4
-
28
-
-
11244281377
-
T-box genes and heart development: putting the "T" in heart
-
Plageman T.F., Yutzey K.E. T-box genes and heart development: putting the "T" in heart. Dev Dyn 2005, 232:11-20.
-
(2005)
Dev Dyn
, vol.232
, pp. 11-20
-
-
Plageman, T.F.1
Yutzey, K.E.2
-
29
-
-
33847344204
-
An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation
-
Prall O.W., Menon M.K., Solloway M.J., et al. An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation. Cell 2007, 128:947-959.
-
(2007)
Cell
, vol.128
, pp. 947-959
-
-
Prall, O.W.1
Menon, M.K.2
Solloway, M.J.3
-
30
-
-
70649083092
-
Recent advances in BMP receptor signaling
-
Sieber C., Kopf J., Hiepen C., Knaus P. Recent advances in BMP receptor signaling. Cytokine Growth Factor Rev 2009, 20:343-355.
-
(2009)
Cytokine Growth Factor Rev
, vol.20
, pp. 343-355
-
-
Sieber, C.1
Kopf, J.2
Hiepen, C.3
Knaus, P.4
-
31
-
-
21644480925
-
Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2
-
Singh M.K., Christoffels V.M., Dias J.M., et al. Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2. Development 2005, 132:2697-2707.
-
(2005)
Development
, vol.132
, pp. 2697-2707
-
-
Singh, M.K.1
Christoffels, V.M.2
Dias, J.M.3
-
32
-
-
70149115439
-
Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal
-
Singh R., Horsthuis T., Farin H.F., et al. Tbx20 interacts with smads to confine tbx2 expression to the atrioventricular canal. Circ Res 2009, 105:442-452.
-
(2009)
Circ Res
, vol.105
, pp. 442-452
-
-
Singh, R.1
Horsthuis, T.2
Farin, H.F.3
-
33
-
-
33748621746
-
Making or breaking the heart: from lineage determination to morphogenesis
-
Srivastava D. Making or breaking the heart: from lineage determination to morphogenesis. Cell 2006, 126:1037-1048.
-
(2006)
Cell
, vol.126
, pp. 1037-1048
-
-
Srivastava, D.1
-
34
-
-
0141615095
-
Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart
-
Stennard F.A., Costa M.W., Elliott D.A., et al. Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. Dev Biol 2003, 262:206-224.
-
(2003)
Dev Biol
, vol.262
, pp. 206-224
-
-
Stennard, F.A.1
Costa, M.W.2
Elliott, D.A.3
-
35
-
-
21044446280
-
Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation
-
Stennard F.A., Costa M.W., Lai D., et al. Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development 2005, 132:2451-2462.
-
(2005)
Development
, vol.132
, pp. 2451-2462
-
-
Stennard, F.A.1
Costa, M.W.2
Lai, D.3
-
36
-
-
28844438924
-
T-box transcription factors and their roles in regulatory hierarchies in the developing heart
-
Stennard F.A., Harvey R.P. T-box transcription factors and their roles in regulatory hierarchies in the developing heart. Development 2005, 132:4897-4910.
-
(2005)
Development
, vol.132
, pp. 4897-4910
-
-
Stennard, F.A.1
Harvey, R.P.2
-
37
-
-
21044452772
-
Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development
-
Takeuchi J.K., Mileikovskaia M., Koshiba-Takeuchi K., et al. Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. Development 2005, 132:2463-2474.
-
(2005)
Development
, vol.132
, pp. 2463-2474
-
-
Takeuchi, J.K.1
Mileikovskaia, M.2
Koshiba-Takeuchi, K.3
-
38
-
-
0034445182
-
Molecular determinants of atrial and ventricular septal defects and patent ductus arteriosus
-
Vaughan C.J., Basson C.T. Molecular determinants of atrial and ventricular septal defects and patent ductus arteriosus. Am J Med Genet 2000, 97:304-309.
-
(2000)
Am J Med Genet
, vol.97
, pp. 304-309
-
-
Vaughan, C.J.1
Basson, C.T.2
-
39
-
-
0034551683
-
Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2
-
Yamada M., Revelli J.P., Eichele G., et al. Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. Dev Biol 2000, 228:95-105.
-
(2000)
Dev Biol
, vol.228
, pp. 95-105
-
-
Yamada, M.1
Revelli, J.P.2
Eichele, G.3
-
40
-
-
0029850112
-
Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development
-
Zhang H., Bradley A. Mice deficient for BMP2 are nonviable and have defects in amnion/chorion and cardiac development. Development 1996, 122:2977-2986.
-
(1996)
Development
, vol.122
, pp. 2977-2986
-
-
Zhang, H.1
Bradley, A.2
|