Relative influence of testosterone and insulin in the regulation of prostatic cell proliferation and growth

Steroids

Volumn 76, Issue 4, 2011, Pages 416-423

  Vikram, A ^a   Kushwaha, S ^a   Jena, G B ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

Author keywords

Androgens; Diabetes; Insulin; Prostate; Testosterone

Indexed keywords

CASPASE 3; CYCLINE; HORMONE RECEPTOR BLOCKING AGENT; INSULIN; INSULIN RECEPTOR; TESTOSTERONE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CASTRATION; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; HORMONE ACTION; MALE; NONHUMAN; ORGAN WEIGHT; PROSTATE; PROSTATE VENTRAL LOBE; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STREPTOZOCIN DIABETES;

ANIMALS; CASTRATION; CELL PROLIFERATION; DIABETES MELLITUS, EXPERIMENTAL; INSULIN; MALE; ORGAN SIZE; PEPTIDES; PROSTATE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, INSULIN; SIGNAL TRANSDUCTION; STREPTOZOCIN; TESTIS; TESTOSTERONE;

RATTUS;

EID: 79951511000     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2010.12.014     Document Type: Article

References (60)

1. P.C. Marker, A.A. Donjacour, R. Dahiya, and G.R. Cunha Hormonal, cellular, and molecular control of prostatic development Dev Biol 253 2003 165 174 (Pubitemid 36259879)
2. X. Cai, R. Haleem, S. Oram, J. Cyriac, F. Jiang, and J.T. Grayhack High fat diet increases the weight of rat ventral prostate Prostate 49 2001 1 8 (Pubitemid 32807942)
3. E.L. Escobar, M.C. Gomes-Marcondes, and H.F. Carvalho Dietary fatty acid quality affects AR and PPARgamma levels and prostate growth Prostate 69 2009 548 558
4. N.U. Rahman, S. Phonsombat, D. Bochinski, R.E. Carrion, L. Nunes, and T.F. Lue An animal model to study lower urinary tract symptoms and erectile dysfunction: the hyperlipidaemic rat BJU Int 100 2007 658 663 (Pubitemid 47205488)
5. A. Vikram, G. Jena, and P. Ramarao Pioglitazone attenuates prostatic enlargement in diet-induced insulin-resistant rats by altering lipid distribution and hyperinsulinemia Br J Pharmacol 161 2010 1708 1721
6. A. Vikram, G. Jena, and P. Ramarao Insulin-resistance and benign prostatic hyperplasia: the connection Eur J Pharmacol 641 2010 75 81
7. A. Vikram, G. Jena, and P. Ramarao Insulin-resistance reduces botulinum neurotoxin-type A induced prostatic atrophy and apoptosis in rats Eur J Pharmacol 650 2011 356 363
8. A. Vikram, G.B. Jena, and P. Ramarao Increased cell proliferation and contractility of prostate in insulin resistant rats: linking hyperinsulinemia with benign prostate hyperplasia Prostate 70 2010 79 89
9. A. Vikram, D.N. Tripathi, P. Ramarao, and G.B. Jena Intervention of d-glucose ameliorates the toxicity of streptozotocin in accessory sex organs of rat Toxicol Appl Pharmacol 226 2008 84 93 (Pubitemid 350235584)
10. S.E. Dahle, A.P. Chokkalingam, Y.T. Gao, J. Deng, F.Z. Stanczyk, and A.W. Hsing Body size and serum levels of insulin and leptin in relation to the risk of benign prostatic hyperplasia J Urol 168 2002 599 604 (Pubitemid 34793304)
11. J. Hammarsten, and B. Hogstedt Hyperinsulinaemia as a risk factor for developing benign prostatic hyperplasia Eur Urol 39 2001 151 158 (Pubitemid 32171181)
12. H. Nandeesha, B.C. Koner, L.N. Dorairajan, and S.K. Sen Hyperinsulinemia and dyslipidemia in non-diabetic benign prostatic hyperplasia Clin Chim Acta 370 2006 89 93 (Pubitemid 44080171)
13. C. Ozden, O.L. Ozdal, G. Urgancioglu, H. Koyuncu, S. Gokkaya, and A. Memis The correlation between metabolic syndrome and prostatic growth in patients with benign prostatic hyperplasia Eur Urol 51 2007 199 203
14. J.K. Parsons, H.B. Carter, A.W. Partin, B.G. Windham, E.J. Metter, and L. Ferrucci Metabolic factors associated with benign prostatic hyperplasia J Clin Endocrinol Metab 91 2006 2562 2568 (Pubitemid 44024618)
15. S. Kasturi, S. Russell, and K.T. McVary Metabolic syndrome and lower urinary tract symptoms secondary to benign prostatic hyperplasia Curr Urol Rep 7 2006 288 292 (Pubitemid 44623991)
16. W.L. McKeehan, P.S. Adams, and M.P. Rosser Direct mitogenic effects of insulin, epidermal growth factor, glucocorticoid, cholera toxin, unknown pituitary factors and possibly prolactin, but not androgen, on normal rat prostate epithelial cells in serum-free, primary cell culture Cancer Res 44 1984 1998 2010 (Pubitemid 14145145)
17. W. Fan, T. Yanase, H. Morinaga, T. Okabe, M. Nomura, and H. Daitoku Insulin-like growth factor 1/insulin signaling activates androgen signaling through direct interactions of Foxo1 with androgen receptor J Biol Chem 282 2007 7329 7338 (Pubitemid 47093686)
18. M. Yono, S.M. Mane, A. Lin, R.M. Weiss, and J. Latifpour Differential effects of diabetes induced by streptozotocin and that develops spontaneously on prostate growth in bio breeding (BB) rats Life Sci 83 2008 192 197
19. M. Yono, M. Pouresmail, W. Takahashi, J.F. Flanagan, R.M. Weiss, and J. Latifpour Effect of insulin treatment on tissue size of the genitourinary tract in BB rats with spontaneously developed and streptozotocin-induced diabetes Naunyn Schmiedebergs Arch Pharmacol 372 2005 251 255 (Pubitemid 41668755)
20. A. Vikram, and G. Jena Role of insulin and testosterone in prostatic growth: who is doing what? Med Hypotheses 2010
21. J.M. Fitts, R.M. Klein, and C.A. Powers Comparison of tamoxifen and testosterone propionate in male rats: differential prevention of orchidectomy effects on sex organs, bone mass, growth, and the growth hormone-IGF-I axis J Androl 25 2004 523 534 (Pubitemid 38880188)
22. I. Franck-Lissbrant, S. Haggstrom, J.E. Damber, and A. Bergh Testosterone stimulates angiogenesis and vascular regrowth in the ventral prostate in castrated adult rats Endocrinology 139 1998 451 456 (Pubitemid 28513188)
23. S.H. Rudolfsson, and A. Bergh Testosterone-stimulated growth of the rat prostate may be driven by tissue hypoxia and hypoxia-inducible factor-1alpha J Endocrinol 196 2008 11 19 (Pubitemid 351234567)
24. M. Thiyagarajan, C.L. Kaul, and P. Ramarao Enhancement of alpha-adrenoceptor-mediated responses in prostate of testosterone-treated rat Eur J Pharmacol 453 2002 335 344 (Pubitemid 35223527)
25. R. Doggweiler, D.H. Zermann, M. Ishigooka, and R.A. Schmidt Botox-induced prostatic involution Prostate 37 1998 44 50 (Pubitemid 28385184)
26. D.J. Macleod, R.M. Sharpe, M. Welsh, M. Fisken, H.M. Scott, and G.R. Hutchison Androgen action in the masculinization programming window and development of male reproductive organs Int J Androl 33 2010 279 287
27. C.A. Peters, and P.C. Walsh The effect of nafarelin acetate, a luteinizing-hormone-releasing hormone agonist, on benign prostatic hyperplasia N Engl J Med 317 1987 599 604 (Pubitemid 17118986)
28. G.S. Prins, and K.S. Korach The role of estrogens and estrogen receptors in normal prostate growth and disease Steroids 73 2008 233 244
29. J. Hammarsten, and B. Hogstedt Clinical, anthropometric, metabolic and insulin profile of men with fast annual growth rates of benign prostatic hyperplasia Blood Press 8 1999 29 36 (Pubitemid 29278945)
30. K. McVary Lower urinary tract symptoms and sexual dysfunction: epidemiology and pathophysiology BJU Int 97 Suppl. 2 2006 23 28 (Pubitemid 43356992)
31. H. Nandeesha Benign prostatic hyperplasia: dietary and metabolic risk factors Int Urol Nephrol 40 2008 649 656
32. A.V. Sarma, and J. Kellogg Parsons Diabetes and benign prostatic hyperplasia: emerging clinical connections Curr Urol Rep 10 2009 267 275
33. P.C. Walsh Experimental approaches to benign prostatic hypertrophy: animal models utilizing the dog, rat, and mouse, In Benign Prostatic Hyperplasia NIAMDD Workshop Proc 1975 215 222
34. C.B. Brendler, S.J. Berry, L.L. Ewing, A.R. McCullough, R.C. Cochran, and J.D. Strandberg Spontaneous benign prostatic hyperplasia in the beagle. Age-associated changes in serum hormone levels, and the morphology and secretory function of the canine prostate J Clin Invest 71 1983 1114 1123 (Pubitemid 13098898)
35. A.M. De Marzo, D.S. Coffey, and W.G. Nelson New concepts in tissue specificity for prostate cancer and benign prostatic hyperplasia Urology 53 1999 29 39
36. P.P. Banerjee, S. Banerjee, J.M. Lai, J.D. Strandberg, B.R. Zirkin, and T.R. Brown Age-dependent and lobe-specific spontaneous hyperplasia in the brown Norway rat prostate Biol Reprod 59 1998 1163 1170 (Pubitemid 28498928)
37. J. Kim, Y. Yanagihara, T. Kikugawa, M. Ji, N. Tanji, and Y. Masayoshi A signaling network in phenylephrine-induced benign prostatic hyperplasia Endocrinology 150 2009 3576 3583
38. L.W. Chung, J. Matsuura, A.K. Rocco, T.C. Thompson, G.J. Miller, and M.N. Runner A new mouse model for prostatic hyperplasia: induction of adult prostatic overgrowth by fetal urogenital sinus implants Prog Clin Biol Res 145 1984 291 306
39. K. Pelton, D. Di Vizio, L. Insabato, C.P. Schaffner, M.R. Freeman, and K.R. Solomon Ezetimibe reduces enlarged prostate in an animal model of benign prostatic hyperplasia J Urol 184 2010 1555 1559
40. S. Kobayashi, Y. Tomiyama, S. Tatemichi, Y. Hoyano, M. Kobayashi, and Y. Yamazaki Effects of silodosin and tamsulosin on the urethra and cardiovascular system in young and old dogs with benign prostatic hyperplasia Eur J Pharmacol 613 2009 135 140
41. W. Mahapokai, F.J. Van Sluijs, and J.A. Schalken Models for studying benign prostatic hyperplasia Prostate Cancer Prostatic Dis 3 2000 28 33 (Pubitemid 30616516)
42. K. Nanda, K.S. Naruganahalli, S. Gupta, S. Malhotra, A. Tiwari, and L.G. Hegde RBx 6198: a novel alpha1-adrenoceptor antagonist for the treatment of benign prostatic hyperplasia Eur J Pharmacol 607 2009 213 219
43. S.V. Veeresh Babu, B. Veeresh, A.A. Patil, and Y.B. Warke Lauric acid and myristic acid prevent testosterone induced prostatic hyperplasia in rats Eur J Pharmacol 626 2010 262 265
44. E. Golomb, N. Rosenzweig, R. Eilam, and A. Abramovici Spontaneous hyperplasia of the ventral lobe of the prostate in aging genetically hypertensive rats J Androl 21 2000 58 64 (Pubitemid 30069082)
45. K. Ikeda, Y. Wada, H.E. Foster Jr., Z. Wang, R.M. Weiss, and J. Latifpour Experimental diabetes-induced regression of the rat prostate is associated with an increased expression of transforming growth factor-beta J Urol 164 2000 180 185 (Pubitemid 30434297)
46. Y. Homma, Y. Kondo, M. Kaneko, T. Kitamura, W.T. Nyou, and M. Yanagisawa Promotion of carcinogenesis and oxidative stress by dietary cholesterol in rat prostate Carcinogenesis 25 2004 1011 1014 (Pubitemid 38886086)
47. K. Ploumidou, A. Kyroudi-Voulgari, D. Perea, I. Anastasiou, and D. Mitropoulos Effect of a hypercholesterolemic diet on serum lipid profile, plasma sex steroid levels, and prostate structure in rats Urology 2010
48. T.L. Ratliff Promotion of carcinogenesis and oxidative stress by dietary cholesterol in rat prostate J Urol 173 2005 1044 1045
49. L. Xue, K. Yang, H. Newmark, and M. Lipkin Induced hyperproliferation in epithelial cells of mouse prostate by a Western-style diet Carcinogenesis 18 1997 995 999 (Pubitemid 28132345)
50. A. Tsujimura, Y. Koikawa, S. Salm, T. Takao, S. Coetzee, and D. Moscatelli Proximal location of mouse prostate epithelial stem cells: a model of prostatic homeostasis J Cell Biol 157 2002 1257 1265 (Pubitemid 34851270)
51. X. Wang, M. Kruithof-de Julio, K.D. Economides, D. Walker, H. Yu, and M.V. Halili A luminal epithelial stem cell that is a cell of origin for prostate cancer Nature 461 2009 495 500
52. E. Suthagar, S. Soudamani, S. Yuvaraj, A. Ismail Khan, M.M. Aruldhas, and K. Balasubramanian Effects of streptozotocin (STZ)-induced diabetes and insulin replacement on rat ventral prostate Biomed Pharmacother 63 2009 43 50
53. W.J. Favaro, C.R. Padovani, and V.H. Cagnon Ultrastructural and proliferative features of the ventral lobe of the prostate in non-obese diabetic mice (NOD) following androgen and estrogen replacement associated to insulin therapy Tissue Cell 41 2009 119 132
54. W.J. Favaro, and V.H. Cagnon Effect of combined hormonal and insulin therapy on the steroid hormone receptors and growth factors signalling in diabetic mice prostate Int J Exp Pathol 91 2010 537 547
55. S. Srinivasan, and Z. Nawaz E3 ubiquitin protein ligase, E6-associated protein (E6-AP) regulates PI3K-Akt signaling and prostate cell growth Biochim Biophys Acta 2010
56. J. Svensson, J. Kindblom, R. Shao, S. Moverare-Skrtic, M.K. Lagerquist, and N. Andersson Liver-derived IGF1 enhances the androgenic response in prostate J Endocrinol 199 2008 489 497
57. S.A. Paranjape, O. Chan, W. Zhu, A.M. Horblitt, E.C. McNay, and J.A. Cresswell Influence of insulin in the ventromedial hypothalamus on pancreatic glucagon secretion in vivo Diabetes 59 2010 1521 1527
58. L. Schaffer, C.L. Brand, B.F. Hansen, U. Ribel, A.C. Shaw, and R. Slaaby A novel high-affinity peptide antagonist to the insulin receptor Biochem Biophys Res Commun 376 2008 380 383
59. A. Vikram, and G. Jena S961, an insulin receptor antagonist causes hyperinsulinemia, insulin-resistance and depletion of energy stores in rats Biochem Biophys Res Commun 398 2010 260 265
60. D.M. Damas-Souza, C.A. Oliveira, and H.F. Carvalho Insulin affects tissue organization and the kinetics of epithelial cell death in the rat ventral prostate after castration J Androl 2010