Structure of the putative dihydroorotate dehydrogenase from Streptococcus mutans

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 67, Issue 2, 2011, Pages 182-187

  Liu, Ying ^a,b   Gao, Zeng Qiang ^b   Liu, Chao Pei ^b   Xu, Jian Hua ^b   Li, Lan Fen ^c   Ji, Chao Neng ^a   Su, Xiao Dong ^c   Dong, Yu Hui ^b  

^a FUDAN UNIVERSITY   (China)

^b INSTITUTE OF HIGH ENERGY PHYSICS   (China)

^c PEKING UNIVERSITY   (China)

Author keywords

Dihydroorotate dehydrogenases; Pyrimidine biosynthesis; Streptococcus mutans

Indexed keywords

DIHYDROOROTATE DEHYDROGENASE; FLAVINE MONONUCLEOTIDE; HISTIDINE; LYSINE; OROTIC ACID; OXIDOREDUCTASE; PROTEIN SUBUNIT; PYRIMIDINE DERIVATIVE; RECOMBINANT PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; BIOSYNTHESIS; CATALYSIS; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; CLASSIFICATION; COMPARATIVE STUDY; DENTAL CARIES; DIMERIZATION; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; HUMAN; METABOLISM; METHODOLOGY; METHYLATION; MICROBIOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; SEQUENCE HOMOLOGY; STREPTOCOCCUS MUTANS; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DENTAL CARIES; DIMERIZATION; ESCHERICHIA COLI; FLAVIN MONONUCLEOTIDE; HISTIDINE; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; LYSINE; METHYLATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OROTIC ACID; OXIDATION-REDUCTION; OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; PYRIMIDINES; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; STREPTOCOCCUS MUTANS; SUBSTRATE SPECIFICITY; X-RAY DIFFRACTION;

STREPTOCOCCUS MUTANS;

EID: 79951501945     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309110048414     Document Type: Article

References (21)

1. Andersen, P. S., Jansen, P. J. G. &Hammer, K. (1994). J. Bacteriol. 176, 3975-3982.
2. Andersen, P. S., Jansen, P. J. G. &Hammer, K. (1996). J. Bacteriol. 178, 5005-5012.
3. Arakaki, T. L., Buckner, F. S., Gillespie, J. R., Malmquist, N. A., Phillips,M. A., Kalyuzhniy, O., Luft, J. R., DeTitta, G. T., Verlinde, C. L. M. J., Van Voorhis, W. C., Holl, W. G. J. &Merritt, E. A. (2008). Mol. Microbiol. 68, 37-50.
4. Baud, F. &Karlin, S. (1999). Proc. Natl Acad. Sci. USA, 96, 12494-12949.
5. Bradford, M. M. (1976). Anal. Biochem. 72, 248-254.
6. Collaborative Computational Project, Number 4 (1994). Acta Cryst. D50, 760-763.
7. DeLano, W. L. (2002). PyMOL. http://www.pymol.org.
8. Emsley, P. &Cowtan, K. (2004). Acta Cryst. D60, 2126-2132.
9. Gouet, P., Courcelle, E., Stuart, D. I. &Métoz, F. (1999). Bioinformatics, 15, 305-308.
10. Hansen, M., Le Nours, J., Johansson, E., Antal, T., Ullrich, A., Löffler, M. &
11. Larsen, S. (2004). Protein Sci. 13, 1031-1042.
12. Jensen, K. F. &Bjornberg, O. (1998). Paths Pyrimidines, 6, 20-28.
13. Larkin, M. A., Blackshields, G., Brown, N. P., Chenna, R., McGettigan, P. A., McWilliam, H., Valentin, F., Wallace, I. M.,Wilm, A., Lopez, R., Thompson, J. D., Gibson, T. J. &Higgins, D. G. (2007). Bioinformatics, 23, 2947-2948.
14. Laskowski, R. A., MacArthur, M. W., Moss, D. S. &Thornton, J. M. (1993). J. Appl. Cryst. 26, 283-291.
15. Liu, S., Neidhardt, E. A., Grossman, T. H., Ocain, T. &Clardy, J. (2000). Structure Fold. Des. 8, 25-33.
16. McCoy, A. J., Grosse-Kunstleve, R. W., Adams, P. D., Winn, M. D., Storoni, L. C. &Read, R. J. (2007). J. Appl. Cryst. 40, 658-674.
17. Otwinowski, Z. &Minor, W. (1997). Methods Enzymol. 276, 307-326.
18. Rowland, P., Nielsen, F. S., Jensen, K. F. &Larsen, S. (1997). Structure, 5, 239-252.
19. Stein, N. (2008). J. Appl. Cryst. 41, 641-643.
20. Su, X.-D., Liang, Y., Li, L., Nan, J., Bröstromer, E., Liu, P., Dong, Y. &Xian, D. (2006). Acta Cryst. D62, 843-851.
21. Walter, T. S., Meier, C., Assenberg, R., Au, K. F., Ren, J.-S., Verma, A., Nettleship, J. E., Owens, R. J., Stuart, D. I. &Grimes, J. M. (2006). Structure, 14, 1617-1622.