Differential regulation of the cellulase transcription factors XYR1, ACE2, and ACE1 in trichoderma reesei strains producing high and low levels of cellulase

Eukaryotic Cell

Volumn 10, Issue 2, 2011, Pages 262-271

  Portnoy, Thomas ^a,c   Margeot, Antoine ^a   Seidl Seiboth, Verena ^b   Le Crom, Stéphane ^c   Chaabane, Fadhel Ben ^a   Linke, Rita ^b   Seiboth, Bernhard ^b   Kubicek, Christian P ^b  

^a IFP ENERGIES NOUVELLES   (France)

^b VIENNA UNIVERSITY OF TECHNOLOGY   (Austria)

^c PSL RESEARCH UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOCREA JECORINA;

EID: 79951497471     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00208-10     Document Type: Article

References (41)

1. Akel, E., B. Metz, B. Seiboth, and C. P. Kubicek. 2009. Molecular regulation of arabinan and L-arabinose metabolism in Hypocrea jecorina (Trichoderma reesei). Eukaryot. Cell 8:1837-1844.
2. Antoni, D., V. V. Zverlov, and W. H. Schwarz. 2007. Biofuels from microbes. Appl. Microbiol. Biotechnol. 77:23-35.
3. Aro, N., M. Ilmen, A. Saloheimo, and M. Penttila. 2003. ACEI of Trichoderma reesei is a repressor of cellulase and xylanase expression. Appl. Environ. Microbiol. 69:56-65.
4. Aro, N., T. Pakula, and M. Penttila. 2005. Transcriptional regulation of plant cell wall degradation by filamentous fungi. FEMS Microbiol. Rev. 29:719-739.
5. Aro, N., A. Saloheimo, M. Ilmen, and M. Penttila. 2001. ACEII, a novel transcriptional activator involved in regulation of cellulase and xylanase genes of Trichoderma reesei. J. Biol. Chem. 276:24309-24314.
6. Belinchón, M. M., and J. M. Gancedo. 2003. Xylose and some non-sugar carbon sources cause catabolite repression in Saccharomyces cerevisiae. Arch. Microbiol. 180:293-297.
7. Brunner, K., et al. 2008. Trichoderma G protein-coupled receptors: functional characterisation of a cAMP receptor-like protein from Trichoderma atroviride. Curr. Genet. 54:283-299.
8. Chang, M. C. 2007. Harnessing energy from plant biomass. Curr. Opin. Chem. Biol. 11:677-684.
9. Durand, H., M. Clanet, and G. Tiraby. 1988. Genetic improvement of Trichoderma reesei for large scale cellulase production. Enzyme Microb. Technol. 10:341-346.
10. Eveleigh, D. E., and B. S. Montenecourt. 1979. Increasing yields of extracellular enzymes. Adv. Appl. Microbiol. 25:57-74.
11. Foreman, P. K., et al. 2003. Transcriptional regulation of biomass-degrading enzymes in the filamentous fungus Trichoderma reesei. J. Biol. Chem. 278: 31988-31997.
12. Furukawa, T., et al. 2009. Identification of specific binding sites for XYR1, a transcriptional activator of cellulolytic and xylanolytic genes in Trichoderma reesei. Fungal Genet. Biol. 46:564-574.
13. Herpoël-Gimbert, I., et al. 2008. Comparative secretome analyses of two Trichoderma reesei RUT-C30 and CL847 hypersecretory strains. Biotechnol. Biofuels 1:18.
14. Ilmén, M., C. Thrane, and M. Penttila. 1996. The glucose repressor gene cre1 of Trichoderma: isolation and expression of a full-length and a truncated mutant form. Mol. Gen. Genet. 251:451-460.
15. Karaffa, L., et al. 2006. D-Galactose induces cellulase gene expression in Hypocrea jecorina at low growth rates. Microbiology 152:1507-1514.
16. Kubicek, C. P., M. Mikus, A. Schuster, M. Schmoll, and B. Seiboth. 2009. Metabolic engineering strategies for the improvement of cellulase production by Hypocrea jecorina. Biotechnol. Biofuels 2:19.
17. Kumar, R., S. Singh, and O. V. Singh. 2008. Bioconversion of lignocellulosic biomass: biochemical and molecular perspectives. J. Ind. Microbiol. Biotechnol. 35:377-391.
18. Le Crom, S., et al. 2009. Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing. Proc. Natl. Acad. Sci. U. S. A. 106:16151-16156.
19. Mach-Aigner, A. R., et al. 2008. Transcriptional regulation of xyr1, encoding the main regulator of the xylanolytic and cellulolytic enzyme system in Hypocrea jecorina. Appl. Environ. Microbiol. 74:6554-6562.
20. Mandels, M., and R. E. Andreotti. 1978. Problems and challenges in the cellulose to cellulase fermentation. Process Biochem. 13:6-15.
21. Martinez, D., et al. 2008. Genome sequencing and analysis of the biomassdegrading fungus Trichoderma reesei (syn. Hypocrea jecorina). Nat. Biotechnol. 26:553-560.
22. Mogensen, J., H. B. Nielsen, G. Hofmann, and J. Nielsen. 2006. Transcription analysis using high-density micro-arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol. Fungal Genet. Biol. 43:593-603.
23. Montenecourt, B. S., and D. E. Eveleigh. 1977. Preparation of mutants of Trichoderma reesei with enhanced cellulase production. Appl. Environ. Microbiol. 34:777-782.
24. Nakari-Setälä, T., et al. 2009. Genetic modification of carbon catabolite repression in Trichoderma reesei for improved protein production. Appl. Environ. Microbiol. 75:4853-4860.
25. Percival Zhang, Y. H., M. E. Himmel, and J. R. Mielenz. 2006. Outlook for cellulase improvement: screening and selection strategies. Biotechnol. Adv. 24:452-481.
26. Prathumpai, W., M. McIntyre, and J. Nielsen. 2004. The effect of CreA in glucose and xylose catabolism in Aspergillus nidulans. Appl. Microbiol. Biotechnol. 63:748-753.
27. Ptashne, M. 1988. How eukaryotic transcriptional activators work. Nature 335:683-689.
28. Schafner, D. W., and R. T. Toledo. 1992. Cellulase production in continuous culture by Trichoderma reesei on xylose-based media. Biotechnol. Bioeng. 39:865-869.
29. Seiboth, B., C. Gamauf, M. Pail, L. Hartl, and C. P. Kubicek. 2007. The D-xylose reductase of Hypocrea jecorina is the major aldose reductase in pentose and D-galactose catabolism and necessary for beta-galactosidase and cellulase induction by lactose. Mol. Microbiol. 66:890-900.
30. Seiboth, B., et al. 2004. The galactokinase of Hypocrea jecorina is essential for cellulase induction by lactose but dispensable for growth on D-galactose. Mol. Microbiol. 51:1015-1025.
31. Seiboth, B., et al. 2005. Role of the bga1-encoded extracellular β-galactosidase of Hypocrea jecorina in cellulase induction by lactose. Appl. Environ. Microbiol. 71:851-857.
32. Seiboth, B., B. S. Pakdaman, L. Hartl, and C. P. Kubicek. 2007. Lactose metabolism in filamentous fungi: how to deal with an unknown substrate. Fungal Biol. Rev. 21:42-48.
33. Seidl, V., I. S. Druzhinina, and C. P. Kubicek. 2006. A screening system for carbon sources enhancing β-N-acetylglucosaminidase formation in Hypocrea atroviridis (Trichoderma atroviride). Microbiology 152:2003-2012.
34. Strauss, J., et al. 1995. Cre1, the carbon catabolite repressor protein from Trichoderma reesei. FEBS Lett. 376:103-107.
35. Stricker, A. R., K. Grosstessner-Hain, E. Wurleitner, and R. L. Mach. 2006. Xyr1 (xylanase regulator 1) regulates both the hydrolytic enzyme system and D-xylose metabolism in Hypocrea jecorina. Eukaryot. Cell 5:2128-2137.
36. Stricker, A. R., R. L. Mach, and L. H. de Graaff. 2008. Regulation of transcription of cellulases- and hemicellulases-encoding genes in Aspergillus niger and Hypocrea jecorina (Trichoderma reesei). Appl. Microbiol. Biotechnol. 78:211-220.
37. Stricker, A. R., M. G. Steiger, and R. L. Mach. 2007. Xyr1 receives the lactose induction signal and regulates lactose metabolism in Hypocrea jecorina. FEBS Lett. 581:3915-3920.
38. Stricker, A. R., P. Trefflinger, N. Aro, M. Penttila, and R. L. Mach. 2008. Role of Ace2 (activator of cellulases 2) within the xyn2 transcriptosome of Hypocrea jecorina. Fungal Genet. Biol. 45:436-445.
39. Szewczyk, E., et al. 2006. Fusion PCR and gene targeting in Aspergillus nidulans. Nat. Protoc. 1:3111-3120.
40. Tansey, W. P. 2001. Transcriptional activation: risky business. Genes Dev. 15:1045-1050.
41. Zeilinger, S., M. Schmoll, M. Pail, R. L. Mach, and C. P. Kubicek. 2003. Nucleosome transactions on the Hypocrea jecorina (Trichoderma reesei) cellulase promoter cbh2 associated with cellulase induction. Mol. Genet. Genomics 270:46-55.